2018-02-12T10:30:05-06:00 2017-09-30 930623286 ALDRICH CPAS AND ADVISORS LLP 7676 HAZARD CENTER DRIVE STE 1300 SAN DIEGO CA 92108 990 2016-10-01 330189397 VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO VETE 8586423070 3350 LA JOLLA VILLAGE DR BLDG 13 SAN DIEGO CA 92161 MARIA SITTMANN EXECUTIVE DIRECTOR/CEO 8586423375 2018-02-05 1 ELSA A ROMERO P00485021 7607461560 69.30.50.66 2018-02-05 14:00:51 PS P D3249599D98CC77547F97D51830FE9C3647E5717 720E88AB64A3353D67F50DB471A97B3845377D88 2016 2021-01-29 14:40:06Z MARIA SITTMANN 3350 LA JOLLA VILLAGE DR BLDG 13 SAN DIEGO CA 92161 18835584 0 X WWW.VMRF.ORG X 1989 CA TO ENHANCE THE HEALTH OF VETERANS OF ALL GENERATIONS THROUGH RESEARCH AND EDUCATION. 13 12 214 15 0 0 15134591 14599053 4822249 4194987 17074 41544 0 0 19973914 18835584 0 0 0 0 13277375 12807948 0 0 0 6312511 6649823 19589886 19457771 384028 -622187 8707968 7653771 3876347 3444337 4831621 4209434 X HONORING MILITARY SERVICE WITH SCIENCE; OUR BENCH-TO-BEDSIDE APPROACH HAS LED TO BREAKTHROUGHS IN AREAS SUCH AS SHINGLES PREVENTION, HEART DISEASE, METABOLIC DISEASES AND GROUND BREAKING WORK ON POST-TRAUMATIC STRESS DISORDER. 0 0 3357017 DR. HAMMOND - DISCOVERY AND DEVELOPMENT OF THERAPEUTIC GENES FOR CHF.THE PURPOSE OF THIS PROGRAM, "DISCOVERY & DEVELOPMENT OF THERAPEUTIC GENES FOR CHF" IS TO ENABLE A NUMBER OF SCIENTISTS AT VMRF AND UCSD TO MAINTAIN AN EFFICIENT, INTERACTIVE AND MUTUALLY REINFORCING PROGRAM OF BASIC AND TRANSLATIONAL RESEARCH TO PROMOTE THE DISCOVERY AND DEVELOPMENT OF THERAPEUTIC GENES FOR CONGESTIVE HEART FAILURE (CHF) AND OTHER CARDIOVASCULAR DISEASES. THE PROGRAM WILL FACILITATE THE TRANSITION FROM DISCOVERY TO CLINICAL APPLICATION OF NEW THERAPEUTIC GENES. THIS MODEL COMBINES DISCOVERY RESEARCH WITH PRACTICAL "STREET-SMART" PRECLINICAL DEVELOPMENT. SUCCESSFULLY ATTAINING OUR GOALS WILL REQUIRE SEPARATE BUT HIGHLY INTEGRATED PROJECTS THAT CONTAIN THE PROPER PROPORTIONS OF DISCOVERY RESEARCH AND FOCUSED PRECLINICAL DEVELOPMENT, AN ACCOMPLISHED TRANSLATIONAL PHYSIOLOGY CORE, AND AN INTERACTIVE GROUP OF VMRF AND UCSD PHYSICIAN-SCIENTISTS IN AN IDEAL ENVIRONMENT. 970015 DR. IX - KIDNEY TUBLAR DAMAGE AND DYSFUNCTION IDENTIFY A NOVEL AXIS OF CHRONIC KIDNEYPATHALOGIC STUDIES DEMONSTRATE THAT KIDNEY TUBULE INJURY, ATROPHY, AND FIBROSIS ARE COMMON FEATURES OF CHRONIC KIDNEY DISEASE (CKD) AND ARE HIGHLY PREDICTIVE OF PROGRESSION TO DIALYSIS. ESTABLISHED CKD RISK FACTORS INCLUDING HYPERTENSION AND ADVANCED AGE ARE ASSOCIATED WITH TUBULAR INJURY AND FIBROSIS ON BIOPSY. HOWEVER, CURRENT CLINICAL ASSESSMENT OF CKD EVALUATES ONLY GLOMERULAR FUNCTION (GFR) AND GLOMERULAR INJURY (ALBUMINURIA), BUT NOT KIDNEY TUBULAR DYSFUNCTION OR INJURY. THE OVERALL HYPOTHESIS OF THIS APPLICATION IS THAT KIDNEY TUBULAR DYSFUNCTION AND INJURY ARE MEASURABLE CONTRIBUTORS TO CKD PATHOGENESIS AND PROGNOSIS. DYSFUNCTION OF THE KIDNEY TUBULES WILL BE ASSESSED BY THREE INDICES: (1) RENAL TUBULE RESISTANCE TO HORMONE ACTIONS OF FGF23 AND PTH; (2) ACID/BASE HOMEOSTASIS; AND (3) URINE REABSORPTIVE CAPACITY.WE WILL: (1) DETERMINE THE ASSOCIATION OF KIDNEY TUBULAR DYSFUNCTION AND INJURY WITH RISK OF CKD EVENTS, (2) DETERMINE THE ASSOCIATION OF KIDNEY TUBULAR DYSFUNCTION AND INJURY WITH CKD PROGRESSION, AND (3) DETERMINE WHETHER RANDOMIZATION TO INTENSIVE BLOOD PRESSURE MANAGEMENT ARM OF THE TRIAL SLOWS PROGRESSION OF KIDNEY TUBULAR DYSFUNCTION AND INJURY OVER TIME COMPARED WITH STANDARD BLOOD PRESSURE MANAGEMENT. 970016 DR. BAKER - PATTERNS OF TINNITUS AND HEARING LOSS SECONDARY TO BLAST INJURY.BLAST INJURIES ARE DEEMED SIGNATURE WOUNDS OF RECENT WARS; 12-23% OF RETURNING SERVICE MEMBERS REPORT TRAUMATIC BRAIN INJURY (TBI), THE MAJORITY MILD TBI (MTBI). OF MILITARY PERSONNEL EXPOSED TO EXPLOSIONS, UP TO 77% SUSTAIN PERMANENT HEARING LOSS AND 60-75% REPORT TINNITUS. PATIENTS WITH BLAST-RELATED TRAUMATIC BRAIN INJURY (TBI) ARE AT LEAST 2-1/2 TIMES MORE LIKELY TO SUSTAIN TINNITUS THAN PATIENTS WITH NON-BLAST TBI. DESPITE THE HIGH PREVALENCE OF TINNITUS IT REMAINS A SUBJECTIVE SYNDROME THAT IS NOT WELL CHARACTERIZED AND FOR WHICH THERE IS NO DEFINITIVE TREATMENT. THIS APPLICATION MAKES USE OF THE APPLIED (HUMAN) TBI-RELATED RESEARCH CDMRP REQUEST FOR PROPOSALS TO FOCUS UPON THE AREA OF HEARING LOSS/DYSFUNCTION AND TINNITUS, WITH THE PRIME GOAL BEING TO BETTER UNDERSTAND UNDERLYING NEURAL MECHANISMS OF TINNITUS. 9441275 4194987 VETERANS MEDICAL RESEARCH FOUNDATION OF SAN DIEGO, WHERE WE HONOR SERVICE WITH SCIENCE, IS THE REGION'S ONLY MEDICAL RESEARCH INSTITUTE DEDICATED TO VETERANS. WE FACILITATE WORLD-CLASS RESEARCH AT THE VA SAN DIEGO HEALTHCARE SYSTEM THAT PROVIDES IMPROVEMENTS FOR VETERANS' HEALTHCARE. WHILE FOCUSED ON VETERANS, OUR MEDICAL ADVANCES EXTEND TO THE ENTIRE POPULATION AND RAISE THE STANDARD OF CARE FOR EVERYONE. 9441275 4194987 14738323 1 1 0 1 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 70 0 1 214 1 0 0 0 0 0 0 0 0 0 0 X 13 12 0 0 0 0 0 1 1 1 1 0 0 1 1 1 1 1 1 1 1 0 CA X RON LARSON CFO 8586423069 3350 LA JOLLA VILLAGE DRIVE BLDG 13 SAN DIEGO CA 92161 PHILLIP L JELSMA CHAIRMAN 4.00 X X 20000 0 0 ELAINE MUCHMORE MD VICE PRESIDENT 1.00 X X 0 0 0 KATHLEEN KIM MD MPH DIRECTOR 1.00 X 0 0 0 JACQUELINE PARTHEMORE MD DIRECTOR 1.00 X 0 0 0 PEGGY KEARNS DIRECTOR 1.00 X 0 0 0 ERIC WILSON DIRECTOR 1.00 X 0 0 0 ROBIN SAMIT DIRECTOR 1.00 X 0 0 0 KIRK JORGENSEN DIRECTOR 1.00 X 0 0 0 ROBERT B HALDER MD DIRECTOR 1.00 X 0 0 0 BARBARA NOERENBERG DIRECTOR 1.00 X 0 0 0 GERHARD SCHULTEIS PHD DIRECTOR 1.00 X 0 0 0 ROBERT SMITH MD DIRECTOR 1.00 X 0 0 0 KIRK PETERSON MD DIRECTOR 1.00 X 0 0 0 PETER HEKMAN DIRECTOR 1.00 X 0 0 0 ROBERT ANTHENELLI MD DIRECTOR 1.00 X 0 0 0 MARIA SITTMANN EXECUTIVE DIRECTOR/CEO 40.00 X 236673 0 44573 RONALD LARSON CFO 40.00 X 152220 0 13388 RUTH HARBECKE RESEARCH ASSOCIATE 40.00 X 116045 0 36520 ALMA MUNOZ CANETE PRE AWARD DIRECTOR 40.00 X 116079 0 29860 MARI BRAY VMU DIRECTOR 40.00 X 100831 0 13709 CINDY MATHESON TERM 9117 CONTRACTS & GRANTS DIRECTOR 40.00 X 101329 0 8143 843177 0 146193 6 0 1 0 REGENTS OF THE UNIVERSITY OF CALIFORNIA 9500 GILMAN DRIVE LA JOLLA CA 92093 RESEARCH SERVICES 101364 1 14587089 11964 14599053 RECHARGE INCOME 541700 1908266 1908266 CLINICAL RESEARCH REVENUE 541700 1781087 1781087 GRANT REVENUE 541700 505634 505634 4194987 41544 41544 18835584 4194987 0 41544 X 464236 464236 10869624 8610464 2259160 296982 215763 81219 626286 399229 227057 550820 357734 193086 607163 147959 459204 34310 2900 31410 50200 50200 1385 1385 2795065 2608535 186530 305 305 1782445 1677849 104596 244809 90962 153847 50481 192 50289 67161 60138 7023 122057 122057 137054 84877 52177 147592 29050 118542 230769 230769 OTHER EXPENSES 149908 119879 30029 SALES TAX 140697 127705 12992 POSTAGE AND FREIGHT 69528 63956 5572 PUBLICATION FEES 18894 18769 125 19457771 14738323 4719448 0 715545 931541 3574000 2649000 1073730 942928 2277786 2212843 209518 179868 7476560 6738969 857389 737591 8707968 7653771 1889997 1890928 1986350 1553409 3876347 3444337 X 4431976 3973416 399645 236018 4831621 4209434 8707968 7653771 -622187 0 X 0 1 X 1 1 1 X 20252925 16879741 16690488 15134591 14599053 83556798 20252925 16879741 16690488 15134591 14599053 83556798 83556798 7200 8980 8660 17074 41544 83458 83640256 24193988 0.99900 0.99950 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 0 0 0 0 0 0 0 1 1385 1385 0 PART II-B, LINE 1: VMRF IS A MEMBER OF NAVREF (NATIONAL ASSOCIATION OF VETERAN RESEARCH & EDUCATION FOUNDATIONS), AIRI (ASSOCIATION OF INDEPENDENT RESEARCH INSTITUTES) AND CALIFORNIA CHAMBER OF COMMERCE AND A SMALL PORTION OF THE MEMBERSHIP AMOUNT IS ATTRIBUTED TO LOBBYING. 5747970 5122725 625245 1728590 1616244 112346 737591 X 18835584 0 18835584 0 18835584 19457771 0 19457771 0 19457771 PART X, LINE 2: THE ORGANIZATION RECOGNIZES ACCRUED INTEREST AND PENALTIES ASSOCIATED WITH UNCERTAIN TAX POSITIONS AS PART OF THE INCOME TAX PROVISION, WHEN APPLICABLE. THERE ARE NO AMOUNTS ACCRUED IN THE FINANCIAL STATEMENTS RELATED TO UNCERTAIN TAX POSITIONS FOR THE YEAR ENDED SEPTEMBER 30, 2017. X X X X X 0 0 0 0 0 0 0 0 0 MARIA SITTMANN EXECUTIVE DIRECTOR/CEO 236673 0 0 0 0 0 24000 0 20573 0 281246 0 0 0 RONALD LARSON CFO 152220 0 0 0 0 0 0 0 13388 0 165608 0 0 0 RUTH HARBECKE RESEARCH ASSOCIATE 116045 0 0 0 0 0 12299 0 24221 0 152565 0 0 0 FORM 990, PART VI, SECTION A, LINE 7A THE VETERANS MEDICAL RESEARCH FOUNDATION BOARD OF DIRECTORS INCLUDES FOUR (4) MANDATORY BOARD MEMBERS REPRESENTING THE VA SAN DIEGO HEALTHCARE SYSTEM (VASDHS) AND ONE BOARD MEMBER REPRESENTING VA SOUTHERN NEVADA HEALTHCARE SYSTEM (VASNHS). THESE MEMBERS ARE THE VASDHS DIRECTOR, CHIEF OF STAFF, ASSOCIATE CHIEF OF STAFF FOR RESEARCH AND DEVELOPMENT, THE ASSOCIATE CHIEF OF STAFF FOR EDUCATION, AND THE VASNHS DIRECTOR. ALL OF THESE VAS LEADERS ARE ULTIMATELY HIRED AND APPROVED BY THE DEPARTMENT OF VETERANS AFFAIRS VETERANS HEALTH ADMINISTRATION. FORM 990, PART VI, SECTION A, LINE 7B THE VETERANS MEDICAL RESEARCH FOUNDATION'S BOARD MEMBERS MUST BE SPECIFICALLY APPROVED BY THE DIRECTOR OF VASDHS. THE DIRECTOR OF THE VASDHS IS A VOTING MEMBER OF THE VMRF BOARD OF DIRECTORS AND HAS THE SAME VOTING RIGHTS AS ALL OTHER VOTING MEMBERS. FORM 990, PART VI, SECTION B, LINE 11B AFTER INTERNAL REVIEW BY THE EXECUTIVE DIRECTOR, CFO, AND THE ACCOUNTING DIRECTOR, THE AUDITORS REVIEW THE 990 WITH THE AUDIT COMMITTEE. THE 990 IS THEN DISTRIBUTED TO THE BOARD PRIOR TO FINAL APPROVAL BY THE EXECUTIVE DIRECTOR AND CEO. FORM 990, PART VI, SECTION B, LINE 12C MEMBERS OF THE BOARD OF DIRECTORS AND EXECUTIVE OFFICERS ARE REQUIRED TO COMPLETE AND SIGN A COI DISCLOSURE QUESTIONNAIRE (INCLUDING DISCLOSURE PERTAINING TO SPOUSE OR DEPENDENT CHILDREN) AND TO SIGN A VMRF COI AFFIRMATION OF COMPLIANCE STATEMENT. VMRF'S POLICY ON COI INCLUDES DISCLOSURE REQUIREMENTS, PROCEDURES FOR REVIEW OF POTENTIAL CONFLICTS AND ADDRESSING CONFLICTS OF INTERESTS, AS WELL AS PROVISIONS ON WHAT DISCIPLINARY ACTIONS TO TAKE IN CASE OF VIOLATIONS OF THE BOARD APPROVED COI POLICY. INTERESTED PARTIES WITH A POTENTIAL COI RE: PROPOSED ACTION, POLICY, OR TRANSACTION OF VMRF SHALL NOT PARTICIPATE IN ANY WAY OR BE PRESENT DURING THE DELIBERATION AND DECISION-MAKING FOR SUCH ACTION. ALL ANNUAL BOARD AND KEY EMPLOYEE DISCLOSURE FORMS ARE REVIEWED BY THE EXECUTIVE DIRECTOR. IF THERE ARE CONFLICTS, THEY WILL BE MANAGED AS PER POLICY. THE EXECUTIVE DIRECTOR'S DISCLOSURE IS REVIEWED BY THE BOARD CHAIRMAN AND IF RESEARCH RELATED, BY THE INSTITUTIONAL INDEPENDENT REVIEW BOARD. FORM 990, PART VI, SECTION B, LINE 15 SALARIES OF EXECUTIVE OFFICERS WERE REVIEWED AND RECOMMENDED FOR BOARD APPROVAL BY THE COMPENSATION COMMITTEE. SALARY REVIEWS INCORPORATE PERFORMANCE REVIEW RESULTS AND JOB SPECIFIC COMPARISON SALARY DATA FROM LIKE ORGANIZATIONS, AS WELL AS TWO NATIONAL SALARY SURVEYS. THE TO-BE-EVALUATED PERSON DOES NOT PARTICIPATE IN THE SALARY DISCUSSION OR DECISION MAKING PROCESS AND IS EXCUSED FROM THAT PART OF THE MEETING(S). THE BOARD CHAIRMAN IS THE ONLY PAID BOARD MEMBER AND THE CHAIRMAN'S HONORARIUM WAS BOARD APPROVED. FORM 990, PART VI, SECTION C, LINE 18 IT IS NOTED ON THE WEBSITE THAT THESE DOCUMENTS ARE AVAILABLE UPON REQUEST BY CONTACTING THE VMRF CFO. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION MAKES THE A133 AUDITED FINANCIALS AVAILABLE ONLY IF REQUIRED BY A GRANTOR. FORM 990, PART IX, LINE 11G SUBCONTRACTOR EXPENSES: PROGRAM SERVICE EXPENSES 2,608,535. MANAGEMENT AND GENERAL EXPENSES 186,530. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 2,795,065.