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        <PersonNm>Joel S Marcus start 51517</PersonNm>
        <TitleTxt>Director</TitleTxt>
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        <PersonNm>Mark Pearson</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>Bernard Saint-Donat PhD</PersonNm>
        <TitleTxt>Director</TitleTxt>
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        <PersonNm>Paul Schimmel start 101816</PersonNm>
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        <PersonNm>Christopher T Walsh</PersonNm>
        <TitleTxt>Director (start 10/01/16)</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>Douglas A Bingham</PersonNm>
        <TitleTxt>Secretary/COO</TitleTxt>
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        <PersonNm>Jared M Machado</PersonNm>
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        <PersonNm>Tamara L Barnas</PersonNm>
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        <PersonNm>Richard A King</PersonNm>
        <TitleTxt>Chief Operating Officer</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>Cary E Thomas</PersonNm>
        <TitleTxt>Chief Information Officer</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>James R Williamson</PersonNm>
        <TitleTxt>VP Academic Affairs</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>Kaye I Wynne</PersonNm>
        <TitleTxt>VP Sponsored Programs</TitleTxt>
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        <PersonNm>Ronald L Davis</PersonNm>
        <TitleTxt>Chairman</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>Jeffery W Kelly</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>Richard A Lerner</PersonNm>
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        <PersonNm>Edward Roberts</PersonNm>
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        <PersonNm>Karl Barry Sharpless</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>Steve A Kay</PersonNm>
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        <PersonNm>Thomas E Northrup</PersonNm>
        <TitleTxt>Secretary/General Counsel (end 12/4/15)</TitleTxt>
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        <PersonNm>Jim C Paulson</PersonNm>
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        <PersonNm>Peter K Vogt</PersonNm>
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        <PersonNm>Donna J Weston</PersonNm>
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      <SupplementalInformationDetail>
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      <LicensedStatesCd>SC</LicensedStatesCd>
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        <PersonNm>Peter K Vogt</PersonNm>
        <TitleTxt>Professor/Former Exec VP</TitleTxt>
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        <FormAndLineReferenceDesc>Part I, Line 1a</FormAndLineReferenceDesc>
        <ExplanationTxt>Business travel and first class travel. The Scripps Research Institute allows for business travel for certain key employees for long haul flights. In certain circumstances, business class service is not available on smaller aircraft. In those circumstances, TSRI allows first class travel.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Part I, Lines 4a-b</FormAndLineReferenceDesc>
        <ExplanationTxt>Severance Payments: Cary E. Thomas - $412,600 Thomas E. Northrup - $306,260 Donna J. Weston - $834,147 Part I, Line 4b: Richard Lerner, M.D. participated in a non-qualified deferred compensation plan. Plan terminated 8/31/17.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Schedule K, Part I, Bond Issues:</FormAndLineReferenceDesc>
        <ExplanationTxt>(a) Issue Name: California Infrastructure &amp; Economic Development Bank (f) Description on Purpose: Refund and defease bonds previously issued for the benefit of the Institute on 6/29/2000 and 2/23/2005. Schedule K, Part II, Column A: Issuance-$40,511,601 Refunded-($30,610,696) Defeasance-($9,338,907) Actual Issuance Costs Paid- ($648,704) Schedule K, Part IV, Line 6: This question is being answered without regard to a yield-restricted advance refunding escrow financed with proceeds of the the bonds.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Part I, Column (b):</FormAndLineReferenceDesc>
        <ExplanationTxt>Securities - Publicly traded - No. of contributions</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Part I, Line 32b:</FormAndLineReferenceDesc>
        <ExplanationTxt>Shares of stock gifted to TSRI are transferred into our brokerage account at Salomon Smith Barney and they in turn sell the shares and wire the stock proceeds to TSRI.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VII, Section B:</FormAndLineReferenceDesc>
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        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 11b</FormAndLineReferenceDesc>
        <ExplanationTxt>On June 20, 2018, the Audit Committee reviewed a draft of the Form 990 (including all supplemental schedules). This review included a presentation of the statements by the Chief Financial Officer with particular emphasis on disclosures about governance and about transactions with interested persons. The 990 will be provided to the full Board of Trustees prior to filing.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 12c</FormAndLineReferenceDesc>
        <ExplanationTxt>TSRI'S Conflict of Interest Policies and Procedures apply to members of the Board of Directors, officers, key personnel, and their family members (altogether covered individuals) to protect the interests of TSRI when it is contemplating entering into a transaction or arrangement that could: 1) Benefit the private interest of a covered individual within the meaning of Treasury Regulation Section 1.501(c)(3)-1(d)(1)(ii), 2) Result in a possible excess benefit transaction within the meaning of Section 4958(c) of the Internal Revenue Code of 1986, as amended; or 3) Be a self-dealing transaction within the meaning of Section 5233 of the California Corporations Code (the "Corporations Code"). TSRI's policies and procedures are intended to supplement, but not replace, any state and federal laws governing actual, potential, or apparent conflict of interest applicable to TSRI. Disclosure documents responsive to TSRI's policies are annually submitted by covered individuals, and are reviewed by TSRI administration for pertinent relationships. Any transactions or arrangements involving covered individuals that fall within the scope of the policies are then subject to review and consideration by non-conflicted Board of Director members, with conflicted members being recused from any vote to approve or disapprove.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 15</FormAndLineReferenceDesc>
        <ExplanationTxt>The compensation of the CEO and certain other key executives was reviewed and approved by the Board of Directors. This review was based, in part, on analysis performed by the Human Resources department, and included data from outside consultants or internally-conducted research. On an ongoing basis, executives may participate in the normal annual salary increase program, which is based on a recommendation from the Human Resources department based on market research and approved by the Board of Directors. Any unusual or potentially non-qualified compensation would be reviewed by outside counsel for any tax compliance issues.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section C, line 19</FormAndLineReferenceDesc>
        <ExplanationTxt>Governing documents and Conflict of Interest Policies are not available to the public at this time. The financial statements are available on the TSRI web-site and are filed with the State of Florida by The Scripps Florida Funding Corporation. The statements are provided to bond holders through TSRI's dissemination agent. The annual information return is provided upon request.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Form 990, Part IX, line 11g</FormAndLineReferenceDesc>
        <ExplanationTxt>Purchase Services and Maintenance: Program service expenses 73,140,405. Management and general expenses 2,601,733. Fundraising expenses 364,945. Total expenses 76,107,083.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Form 990, Part XI, line 9:</FormAndLineReferenceDesc>
        <ExplanationTxt>Rounding 13.</ExplanationTxt>
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