2018-05-14T14:08:24-05:00 2017-06-30 814234542 BPM LLP 2000 University Ave Ste 201 East Palo Alto CA 94303 990 2016-07-01 453266802 Cancer Commons CANC 6505303636 5050 El Camino Real 215 Los Altos CA 94022 JAY M TENENBAUM President, Chairman, and Director 6505303636 2018-05-07 1 Tamara L McInerney P00011797 6508556800 2018-05-06 2016 2022-09-23 18:48:47Z JAY M TENENBAUM 5050 El Camino Real 215 Los Altos CA 94022 1424505 0 X www.cancercommons.org X 2011 CA Cancer Commons, by design, is a neutral, patient-centric non-profit clearinghouse that encourages knowledge and data sharing by individual patients and physicians as well as non-profit, commercial, and government entities. We use information technology, Artificial Intelligence (AI), and crowdsourcing to help patients and physicians make the best possible decisions, and continually learn from each patient's results. 6 5 8 9 0 0 810884 1410505 0 14000 8 0 -3172 0 807720 1424505 0 0 0 0 295365 571239 125666 104225 116497 712457 620866 1133488 1296330 -325768 128175 117034 327105 35211 117107 81823 209998 X Cancer Commons aims to ensure that patients and their physicians have the knowledge they need to make the best possible personalized treatment decisions, and to continuously update that knowledge based on each patient's response. 0 0 512538 Cancer Commons provides patient services through its Ask Cancer Commons platform, and through patient content (news, blogs, etc.). Ask Cancer Commons is a web-based service that connects patients with knowledgeable experts in our network, who provide the patients with personalized treatment options, including referrals to top local physicians and to clinical trials. The treatment recommendations and the reasoning that supports them are captured in a registry, along with the patient's clinical history and results. Each case builds on this collective knowledge, enabling more accurate, personalized options for the next community member. Moreover, by continuously learning from the experiences of every participating patient and physician, and immediately applying that knowledge to inform treatment decisions, the Cancer Commons network can explore and optimize the use of available therapies, off-label and in multi-drug therapeutic regimens, far more efficiently than traditional trials. This year, we quadrupled the capacity of our Ask Cancer Commons service. To date, we have helped several thousand patients, throughout the US and in 43 other countries, with all forms of cancer, find new options and hope, and rest assured that no stone has been left unturned. The service is free, made possible by philanthropic support. Demand continues to build, driven almost exclusively by patient referrals on social media, and is now straining the capacity of our current, mostly manual processes. Cancer Commons also develops original patient content and curates third-party publications, news, blog posts, and resources to educate patients and physicians about the latest scientific and clinical findings. This content is made available through our website as well as through social media. In 2016-17, over 3,000 cancer treatment insights and alerts to trials, drug approvals and other actionable developments were generated and disseminated. Patients can also share their clinical data and personal experiences to help other patients learn what patients like them did, how well the treatments worked, and what might be expected during and after treatment. 331095 14000 To scale Ask Cancer Commons, we are growing our network of physicians and scientists, and developing a knowledge sharing platform to continuously learn from every case. The network will soon include molecular tumor boards at elite cancer centers, where the most challenging cases are discussed. Discussions are underway with Yale, UCSD, Stanford, Penn, UCSF, the University of Alabama at Birmingham and Northwestern. Knowledge sharing will initially focus on specific cancer verticals, starting with brain cancer, to quickly amass enough cases to cover the major molecular subtypes and treatment options. This will enable us to move to a technology-driven self-service model where patients and their caregivers can search for cases similar to theirs, and use the treatment recommendations, rationales, and clinical experiences of those patients to inform their own decisions. Each patient then reports what they did and how it worked, to help future patients. This rapid learning approach leverages the personalized research done for one patient to help many others, and uses the experiences of all patients to continuously validate and refine the experts' knowledge. Of course, new patients who require personalized assistance, or who have special needs, will still be able to consult with experts in the Cancer Commons network, and these answers, too, will be integrated into the knowledge base. In 2017, we developed all of the necessary software to support this rapid learning process, including a patient registry, a data repository, and a decision support app. These components capture the expert treatment recommendations from the physicians in our network and use these to identify the best trials, treatments, and combination therapies for future patients. The recommendations are continuously validated and refined based on each patient's results. We're currently piloting this continuous learning process in glioblastoma multiform (GBM), the deadliest form of brain cancer. By the end of 2018, we expect to be advising and learning from more than 100 patients per month.In collaboration with the Musella Foundation, we are also in discussions with the FDA on ways to accelerate the approval of promising investigational drugs for deadly cancers where there are no effective treatments. With their encouragement, we are preparing a bold proposal to allow advanced cancer patients to be treated with such experimental drugs, provided they participate in our patient registry to capture their treatments, outcomes and side-effects. 843633 1 1 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 23 0 8 1 0 0 0 0 0 0 0 0 X 6 5 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 CA X martha dehnow 6502894052 5050 El Camino Real 215 Los Altos CA 94022 X Jay M Tenenbaum Chair, Director, President 40.00 X X 0 0 0 Mikhail Gishizky Director, Treasurer 2.00 X X 0 0 0 Laurence Marton Director 4.00 X 0 0 0 Gladys Monroy Director 2.00 X 0 0 0 Heather Rangel Director 2.00 X 0 0 0 Frank McCormick Director 1.00 X 0 0 0 0 0 0 0 0 0 0 0 1410505 1410505 Program services 541700 14000 14000 14000 1424505 14000 0 0 X 454973 335750 119223 78140 31450 46690 38126 27985 10141 3712 3712 4900 4900 104225 104225 474735 420087 54648 10140 1307 8217 616 1207 1207 77334 77334 14343 11834 1042 1467 9157 8334 823 7447 7447 Software services 13369 6807 550 6012 Service fees 3627 4 269 3354 Moving Expenses 665 665 business expenses 85 85 145 75 70 1296330 843633 336200 116497 87152 294520 10000 10000 4304 2868 11369 3146 3146 0 0 17014 6912 117034 327105 22357 43862 12854 73245 35211 117107 X 81823 209998 81823 209998 117034 327105 128175 0 X 0 0 0 X 1243354 1002604 1352290 810884 1410505 5819637 1243354 1002604 1352290 810884 1410505 5819637 2824321 2995316 5819637 0.51470 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 3146 3146 0 0 ACCRUED PTO 13290 ACCRUED LIABILITIES 60058 ACCRUED PAYROLL -103 73245 X X X X X X X 1 Andrew Sudol 137 E Carmel Valley Road 1 Carmel Valley CA 93924 outreach, cultivation, solicit and track donations, donor re 0 709046 49080 659966 Therese Quinlan 1529 Seaport Blvd Redwood City CA 94063 In charge of strategy, advise/strategize 0 0 21000 -21000 Sandra Noack 1428 Via Don Jose Alamo CA 94507 Donor relations and pledges 0 0 32925 -32925 709046 103005 606041 CA Form 990, Part VI, Section B, line 11b the form 990 is given to the governing body before the return is filed. they review and can request changes at this time. Form 990, Part VI, Section B, line 12c The officers, directors and key employees are required to review and sign the written conflict of interest policy annually. Form 990, Part VI, Section B, line 15 the governance committee performs all interviews specific to top key positions which is then forwarded to the full board of directors for review and approval. Form 990, Part VI, Section C, line 19 made available upon request. Form 990, Part IX, line 11g Payroll Services Related: Program service expenses 0. Management and general expenses 1,545. Fundraising expenses 0. Total expenses 1,545. Outside Contract Services: Program service expenses 418,547. Management and general expenses 50,915. Fundraising expenses 0. Total expenses 469,462. Writers/Editors: Program service expenses 0. Management and general expenses 2,188. Fundraising expenses 0. Total expenses 2,188. Video Production: Program service expenses 1,540. Management and general expenses 0. Fundraising expenses 0. Total expenses 1,540.