2018-05-15T13:22:11-05:00 2017-12-31 042571780 ALEXANDER ARONSON FINNING & CO PC 50 WASHINGTON STREET WESTBOROUGH MA 01581 990 2017-01-01 237376197 HEREDITARY DISEASE FOUNDATION HERE 2129282121 601 WEST 168TH STREET SUITE 54 NEW YORK NY 10032 MEGHAN DONALDSON CEO 2129282121 2018-05-15 1 JOHN BUCKLEY CPA P00830631 5083669100 2018-05-15 2017 2022-09-23 18:48:47Z X MEGHAN DONALDSON 601 WEST 168TH STREET SUITE 54 NEW YORK NY 10032 2627456 0 X HDFOUNDATION.ORG X 1968 CA TO FUND INNOVATIVE RESEARCH TOWARDS CURING HUNTINGTON'S DISEASE AND IMPACTING OTHER BRAIN DISORDERS. 17 15 3 17 0 0 2107686 747377 0 0 288736 432044 -107089 -105152 2289333 1074269 734444 1752844 0 0 492947 374926 0 0 116470 821719 419848 2049110 2547618 240223 -1473349 11731003 11878583 565743 1406338 11165260 10472245 X TO FUND INNOVATIVE RESEARCH TOWARDS CURING HUNTINGTON'S DISEASE AND IMPACTING OTHER BRAIN DISORDERS. 0 0 2207796 1752844 THE HEREDITARY DISEASE FOUNDATION COMMEMORATES ITS 50TH YEAR BY MAKING AN EVEN GREATER IMPACT TOWARD DEVELOPING NOVEL THERAPEUTICS AND CURES. WE HAVE PUT IN PLACE STRATEGIES AND NEW GRANT FUNDING PROGRAMS TO MAXIMIZE OUR EFFECTIVENESS. WE HAVE BEEN FUNDING CATALYTIC AND PARADIGM-CHANGING RESEARCH SINCE OUR BIRTH - INCLUDING IDENTIFYING THE HUNTINGTON'S DISEASE MARKER IN 1983 AND THE HD GENE IN 1993, AND SUPPORTING GENE SILENCING APPROACHES SINCE 2002. WE WANT TO CONTINUE TO MAKE AN IMPACT BY FUNDING RESEARCH THAT PUSHES THE ENVELOPE. THE HEREDITARY DISEASE FOUNDATION PROVIDES FUNDING FOR RESEARCH THAT ADVANCES THE DISCOVERY AND DEVELOPMENT OF TREATMENTS FOR HUNTINGTON'S DISEASE AND OTHER BRAIN DISORDERS. WE ARE PASSIONATE ABOUT FINDING AND FUNDING THE MOST INNOVATIVE, CREATIVE AND PARADIGM-CHANGING RESEARCH POSSIBLE. THE DATA GENERATED WITH HDF FUNDING OFTEN ALLOWS RESEARCHERS TO GET INITIAL FINDINGS THAT HELP THEM APPLY SUCCESSFULLY FOR LARGER, LONG-TERM FUNDING FROM OTHER FUNDING AGENCIES, INCLUDING THE NATIONAL INSTITUTES OF HEALTH. THE FOUNDATION'S CURRENT FOCUS IS ON 1) MODIFIER STUDIES - ON DNA REPAIR PATHWAYS, PROTEIN DEGRADATION AND OTHER MODIFIERS OF PHENOTYPE AND AGE OF ONSET AND 2) RESEARCH MECHANISMS OF HD NEURODEGENERATION AND BIOMARKERS AND THERAPY FOR HD-INDUCED NEURODEGENERATION.TYPE OF FUNDING:THE BASIC RESEARCH GRANTS PROGRAM: SUPPORTS PROJECTS CONTRIBUTING TO IDENTIFYING AND UNDERSTANDING THE FUNDAMENTAL DEFECTS IN HUNTINGTON'S DISEASE.POSTDOCTORAL FELLOWSHIPS: THESE POSTDOCTORAL FELLOWSHIPS ARE INTENDED TO CULTIVATE INTEREST IN HUNTINGTON'S DISEASE RESEARCH BY BRIGHT YOUNG SCIENTISTS. FELLOWSHIPS ARE GRANTED TO THOSE WHO POSSESS IMAGINATION, RIGOR, CREATIVITY AND SPIRIT TO PUSH FORWARD TOWARD A CURE FOR HD AND ENSURE THAT THESE LEARNING CAN BE APPLIED TO OTHER BRAIN DISEASES. 2207796 1 1 0 0 0 0 0 0 0 1 1 0 0 0 0 1 1 0 0 0 1 0 1 1 1 0 0 1 1 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 3 1 0 0 0 0 0 1 1 0 0 0 0 X 17 15 1 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 0 1 1 0 NY CA X MEGHAN DONALDSON 2129282121 601 WEST 168TH STREET SUITE 54 NEW YORK NY 10032 MEGHAN DONALDSON CEO 40.00 X X 99211 0 0 NANCY S WEXLER PHD PRESIDENT 7.00 X X 0 0 0 ALICE WEXLER PHD SECRETARY 1.00 X X 0 0 0 FRANK O GEHRY DIRECTOR 1.00 X 0 0 0 DAVID HOUSMAN PHD DIRECTOR 1.00 X 0 0 0 JOAN LEIMAN DIRECTOR 1.00 X 0 0 0 HERBERT PARDES MD DIRECTOR 2.00 X 0 0 0 ANNE B YOUNG MD PHD VICE CHAIR 1.00 X X 0 0 0 DAVID ZWALLY CHAIR 1.00 X X 0 0 0 ROBI BLUMENSTEIN DIRECTOR 1.00 X 0 0 0 BRUCE DONALDSON TREASURER 1.00 X 0 0 0 SANDY FOX DIRECTOR 1.00 X 0 0 0 BERTA A GEHRY DIRECTOR 1.00 X 0 0 0 DAVID GERSTENHABER DIRECTOR 1.00 X 0 0 0 KELLY POSNER GERSTENHABER PHD DIRECTOR 1.00 X 0 0 0 ARTHUR GOLDING MD DIRECTOR 1.00 X 0 0 0 KAREN NEWMAN DIRECTOR 1.00 X 0 0 0 TRAVIS CAREY CHIEF FINANCIAL OFFICER 10.00 X 0 0 0 99211 0 0 0 0 0 0 0 405562 341815 747377 265653 265653 1562628 1396237 166391 166391 166391 51798 405562 156950 -105152 -105152 1074269 0 0 326892 322188 322188 1165941 1165941 264715 264715 162212 94648 52682 14882 154424 106113 17426 30885 37454 25281 4682 7491 20836 13430 3905 3501 20100 20100 56666 56666 26904 26904 74427 24200 16963 33264 174146 132351 17415 24380 4052 2023 6 2023 42938 42938 11532 8539 2993 MISCELLANEOUS 5618 1964 3610 44 MEDICAL SUPPLIES 3465 3465 2547618 2207796 223352 116470 820716 400213 1245563 1264526 568408 272243 438606 438606 0 0 9075265 9921525 21051 20076 11731003 11878583 5633 18749 560110 1387589 565743 1406338 X 221477 1219266 2418783 727979 8525000 8525000 11165260 10472245 11731003 11878583 -1473349 780334 0 X X 0 1 X 1 0 X 1120348 2670705 1886920 2107686 747377 8533036 1120348 2670705 1886920 2107686 747377 8533036 2377020 6156016 263221 305949 267915 273233 265653 1375971 9909007 0.62130 0.65180 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 7700419 1155712 454459 8401672 7566144 580315 446040 7700419 8250520 -225617 458759 7566144 8512186 205358 467024 8250520 7703889 1233025 424728 8512186 1.00000 0 0 401737 401737 0 36869 36869 0 0 X 2057887 780334 103000 883334 1174553 56666 -156950 -100284 1074269 2750902 103000 156950 259950 2490952 56666 56666 2547618 PART V, LINE 4: THE FOUNDATION INTENDS TO USE THE ENDOWMENT FUNDS FOR ITS SCIENTIFIC ACTIVITIES WHICH INCLUDES PROVIDING GRANTS TO FUND SCIENTIFIC RESEARCH TO FURTHER THE UNDERSTANDING OF, AND TO DEVELOP DIAGNOSTICS AND THERAPEUTICS FOR, NEURODEGENERATIVE DISEASES, INCLUDING HUNTINGTON'S DISEASE. PART X, LINE 2: THE FOUNDATION ACCOUNTS FOR UNCERTAINTY IN INCOME TAXES IN ACCORDANCE WITH ASC TOPIC, INCOME TAXES. THIS STANDARD CLARIFIES THE ACCOUNTING FOR UNCERTAINTY IN TAX POSITIONS AND PRESCRIBES A RECOGNITION THRESHOLD AND MEASUREMENT ATTRIBUTE FOR THE FINANCIAL STATEMENTS REGARDING A TAX POSITION TAKEN OR EXPECTED TO BE TAKEN IN A TAX RETURN. THE FOUNDATION HAS DETERMINED THAT THERE ARE NO UNCERTAIN TAX POSITIONS WHICH QUALIFY FOR EITHER RECOGNITION OR DISCLOSURE IN THE FINANCIAL STATEMENTS AT DECEMBER 31, 2017. THE FOUNDATION'S INFORMATION RETURNS ARE SUBJECT TO EXAMINATION BY THE FEDERAL AND STATE JURISDICTIONS. PART XI, LINE 4B - OTHER ADJUSTMENTS: SPECIAL EVENT EXPENSE -156,950. PART XII, LINE 2D - OTHER ADJUSTMENTS: SPECIAL EVENTS EXPENSE 156,950. 1 SOUTH AMERICA - VENEZUELA 1 1 PROGRAM SERVICES OPERATION OF A CLINIC FOR HUNTINGTON'S PATIENTS 14715 LONDON, ENGLAND 1 1 GRANTS TO RECIPIENTS LOCATED IN REGION SCIENTIFIC RESEARCH 100000 OSLO, NORWAY 1 1 GRANTS TO RECIPIENTS LOCATED IN REGION SCIENTIFIC RESEARCH 75000 CHINA 1 1 GRANTS TO RECIPIENTS LOCATED IN REGION SCIENTIFIC RESEARCH 75000 4 4 0 0 4 4 264715 0 264715 CASH GRANT TO ASSIST IN OPERATIONS OF A CLINIC FOR HUNTINGTON'S PATIENTS. VENEZUELA 1 14715 CHECK FMV SCIENTIFIC RESEARCH LONDON, ENGLAND 1 100000 CHECK FMV SCIENTIFIC RESEARCH OSLO, NORWAY 1 75000 CHECK FMV SCIENTIFIC RESEARCH CHINA 1 75000 CHECK FMV 0 0 0 0 0 0 PART I, LINE 2: EXPENSES INCURRED OUTSIDE THE UNITED STATES ARE MONITORED THROUGH THE SUBMISSION OF INVOICES TO THE CENTRAL OFFICE LOCATED IN NEW YORK AS WELL AS THE PRESIDENTS CONSISTENT CONTACT WITH THE PROGRAM DIRECTOR REGARDING PROGRAM ACTIVITIES. X 1 SUSAN QUINLAN MARTIN 350 EAST 55TH STREET NEW YORK NY 10022 FUNDRAISING 0 457360 86020 371340 457360 86020 371340 NY CA GALA 457360 405562 51798 10024 44290 2630 100006 2 457360 405562 51798 10024 44290 2630 100006 156950 -105152 1 NEW YORK GENOME CENTER 101 AVE OF THE AMERICAS NEW YORK NY 10013 210672684 275208 RESEARCH NEW YOUR BRAIN BANK 3959 BROADWAY NEW YORK NY 10032 800496512 46980 RESEARCH RESEARCH 2 SCIENTIFIC RESEARCH 13 1165941 FMV SCIENTIFIC RESEARCH PART I, LINE 2: THE FOUNDATION MONITORS ITS GRANTS BY REQUIRING SCIENCE RESEARCH PROGRESS REPORTS FROM GRANTEES AS A CONDITION TO FURTHER PAYMENTS OF ANY GRANT PAYABLE IN INSTALLMENTS, AND A FINAL REPORT ON COMPLETION OF THE RESEARCH. DAVID HOUSMAN PHD DR. HOUSMAN IS ON THE BOARD OF DIRECTORS OF HEREDITARY DISEASE FOUNDATION 106000 RESEARCH GRANT AWARDED TO DR. HOUSMAN'S LAB AT MIT FORM 990, PART VI, SECTION A, LINE 2 NANCY WEXLER, PRESIDENT, AND ALICE WEXLER, SECRETARY, ARE SISTERS AND BOTH ARE MEMBERS OF THE BOARD OF DIRECTORS. MEGHAN DONALDSON, CEO AND BRUCE DONALDSON, BOARD MEMBER, ARE MARRIED AND ARE BOTH MEMBERS OF THE BOARD OF DIRECTORS. KELLY POSNER GERSTANHABER AND DAIVD GERSTENHABER ARE MARRIED AND ARE BOTH MEMBERS OF THE BOARD OF DIRECTORS. FORM 990, PART VI, SECTION B, LINE 11B THE FOUNDATION PROVIDES THE 990 TO THE BOARD OF DIRECTORS FOR APPROVAL. FORM 990, PART VI, SECTION B, LINE 12C ANNUAL CONFLICT OF INTEREST STATEMENTS ARE CIRCULATED TO ALL OFFICERS, DIRECTORS, AND KEY EMPLOYEES AT THE BOARD OF DIRECTORS MEETING. MANAGEMENT MAINTAINS SIGNED COPIES OF THESE STATEMENTS FOR ALL SUCH INDIVIDUALS TO ENSURE COMPLIANCE WITH THIS POLICY. FORM 990, PART VI, SECTION B, LINE 15 A WRITTEN EMPLOYEE CONTRACT IS ESTABLISHED AND APPROVED BY THE BOARD OR COMPENSATION COMMITTEE. FORM 990, PART VI, SECTION C, LINE 19 THE FOUNDATION MAKES ITS FINANCIAL STATEMENTS AVAILABLE TO THE PUBLIC ON ITS WEBSITE, WWW.HDFOUNDATION.ORG. THE FOUNDATION MAKES ITS GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICY AVAILABLE TO THE PUBLIC UPON REQUEST. FORM 990, PART XII, LINE 2C: THE FOUNDATION'S AUDIT COMMITTEE ASSUMES RESPONSIBILITY FOR THE OVERSIGHT OF THE AUDIT.