2018-11-14T14:17:03-06:00 2017-12-31 910189318 MOSS ADAMS LLP 4747 EXECUTIVE DRIVE SUITE 1300 SAN DIEGO CA 92121 990 2017-01-01 521842938 J CRAIG VENTER INSTITUTE JCRA 8582001800 4120 CAPRICORN LANE LA JOLLA CA 92037 TAI NGUYEN VP OF FINANCE/CFO 8582001800 2018-11-12 1 PATRICIA J MAYER P00188643 8586271400 12.129.7.100 2018-11-12 17:48:59 PS P DA39A3EE5E6B4B0D3255BFEF95601890AFD80709 5AA2B9289D373ED9AECE1682C470BAAD2873C4EE 2017 2019-02-21 02:37:17Z JOHN CRAIG VENTER 4120 CAPRICORN LANE LA JOLLA CA 92037 43563666 0 X WWW.JCVI.ORG X 1993 MD A NON-PROFIT RESEARCH INSTITUTE DEDICATED TO THE ADVANCEMENT OF THE SCIENCE OF GENOMICS, UNDERSTANDING THE IMPLICATIONS FOR SOCIETY, AND COMMUNICATION OF RESULTS TO SCIENTIFIC COMMUNITIES, THE PUBLIC, AND POLICYMAKERS. 9 6 226 9 -153 -153 27058949 20421917 9400 16234 1290352 2830998 107886 23724 28466587 23292873 2133337 1492998 0 0 21212416 18904834 0 0 34018 14362394 11880775 37708147 32278607 -9241560 -8985734 134554206 131946762 35265805 34866745 99288401 97080017 X A NON-PROFIT RESEARCH INSTITUTE DEDICATED TO THE ADVANCEMENT OF THE SCIENCE OF GENOMICS, UNDERSTANDING THE IMPLICATIONS FOR SOCIETY, AND COMMUNICATION OF RESULTS TO SCIENTIFIC COMMUNITIES, THE PUBLIC, AND POLICYMAKERS. 0 0 10634944 664462 0 DEPARTMENT OF HEALTH AND HUMAN SERVICESDURING 2017, JCVI HAD 28 ACTIVE RESEARCH GRANTS AND SIX (6) ACTIVE CONTRACTS FROM AGENCIES WITHIN DHHS. AMONG THESE WAS JCVI'S LARGEST FUNDED PROGRAM, A GRANT FROM THE NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES (NIAID/NIH) TO SERVE AS A GENOME CENTER FOR INFECTIOUS DISEASES (GCID). THE GCID PROGRAM SCOPE INCLUDES ANALYSIS OF VIRAL, BACTERIAL, AND PARASITE PATHOGENS. THE BACTERIAL AND PARASITE PROGRAMS HAVE A PARTICULAR EMPHASES ON ANTIMICROBIAL RESISTANCE. THE BACTERIAL PROGRAM IS FOCUSED ON THE EVOLUTION AND TRANSMISSION OF CARBAPENEM-RESISTANT ENTEROBACTERIACEAE AND OTHER GRAM-NEGATIVE BACTERIA. ALL GENOME SEQUENCE DATA PRODUCED WITH GCID FUNDING IS RAPIDLY DEPOSITED IN PUBLIC REPOSITORIES TO PROMOTE THE WIDEST POSSIBLE USE AMONG RESEARCH SCIENTISTS.OF THE 34 FUNDED AWARDS, 22 INVOLVE FORMAL COLLABORATIVE AGREEMENTS WITH 17 DIFFERENT UNIVERSITIES, RESEARCH INSTITUTES, AND COMPANIES, REFLECTING A HIGHLY INTERACTIVE RESEARCH PORTFOLIO.JCVI, IN COLLABORATION WITH NORTHROP GRUMMAN, SERVES AS THE MAIN DEVELOPER OF THE VIRAL PATHOGEN RESOURCE (WWW.VIPRBRC.ORG) AND THE INFLUENZA RESEARCH DATABASE (WWW.FLUDB.ORG). THESE RESOURCES SERVE AS FREE PUBLIC PORTALS TO A WIDE RANGE OF INFORMATION, DATA, AND ANALYTICAL TOOLS FOR INTERPRETING VIRAL GENOMES IN THE CONTEXT OF DISEASE. OVER 3000 RESEARCHERS THROUGHOUT THE WORLD USE THESE RESOURCES EVERY WEEK.SEVERAL ADDITIONAL DHHS GRANTS AT JCVI ARE RELATED TO HUMAN MICROBIOME STUDIES. THE MICROBIOME IS THE COLLECTION OF MICROBES THAT LIVE IN AND ON THE HUMAN BODY; THESE SPECIES HAVE RECEIVED CONSIDERABLE ATTENTION IN RECENT YEARS BECAUSE A NEW APPRECIATION OF THE COMPLEX ROLES THAT THEY PLAY IN HEALTH AND DISEASE. SOME OF THESE STUDIES ARE AIMED AT BASIC CHARACTERIZATION OF THE COMPOSITION AND ACTIVITY OF THE MICROBIOME, WHILE OTHERS SEEK TO UNDERSTAND THE CONTRIBUTION OF THE MICROBIOME TO THE DEVELOPMENT OF VARIOUS DISEASES INCLUDING ALCOHOLIC HEPATITIS, TYPE 1 DIABETES, DENTAL CARIES, DIARRHEA, AND ESOPHAGEAL CANCER, AMONG OTHERS. THE INSTITUTE ALSO PARTICIPATES IN THE H3AFRICA PROGRAM VIA A COLLABORATION WITH ADDIS ABABA UNIVERSITY, ETHIOPIA, TO STUDY THE SPREAD AND PATHOGENESIS OF TUBERCULOSIS AND HAS A COLLABORATION WITH THE UNIVERSITY OF CAPE TOWN, SOUTH AFRICA, TO TRAIN COLLABORATORS IN HUMAN MICROBIOME ANALYSIS. THE PROGRAM IS SPONSORED BY THE NIH COMMON FUND TO BRING TECHNOLOGICAL RESOURCES AND TRAINING IN A CAPITAL INVESTMENT-INTENSIVE FIELD (GENOMICS) TO THE AFRICAN CONTINENT VIA COLLABORATIONS WITH US SCIENTISTS WITH EXPERTISE IN THIS FIELD. 1830255 256288 0 NATIONAL SCIENCE FOUNDATIONDURING 2017, JCVI HAD 12 ACTIVE RESEARCH GRANTS FROM THE NATIONAL SCIENCE FOUNDATION (NSF). THESE ENCOMPASSED DIVERSE AREAS OF RESEARCH IN ENVIRONMENTAL MICROBIOLOGY, BIOREMEDIATION, COMPUTATIONAL BIOLOGY, AND EDUCATION. JCVI, ALONG WITH OTHER COLLABORATORS, IS THE DEVELOPER AND HOST OF THE ARABIDOPSIS INFORMATION PORTAL A PUBLIC RESOURCE OF INFORMATION ABOUT THIS IMPORTANT MODEL PLANT SPECIES. IN ADDITION TO PROVIDING DATA AND ANALYSIS TOOLS, THE PORTAL OFFERS USERS THE ABILITY TO DESIGN THEIR OWN ANALYTICAL "APPS" THAT CAN BE RUN WITHIN THE SYSTEM ON ALL OF THE DATA ACCESSIBLE THROUGH THE PORTAL, PROVIDING CONSIDERABLE LATITUDE FOR NEW AND INNOVATIVE USES OF THE INFORMATION. ONE LARGE PROGRAM IS DEVOTED TO DEVELOPMENT OF A VACCINE TO PREVENT BOVINE PLEUROPNEUMONIA, AN INFECTIOUS DISEASE OF CATTLE IN SUB-SAHARAN AFRICA. SEVERAL GRANTS PERTAIN TO ENVIRONMENTAL MICROBIOLOGY, ANALYZING THE ROLES OF MICROBES IN IMPORTANT ECOSYSTEMS THROUGHOUT THE WORLD. 1240363 235375 0 DEPARTMENT OF DEFENSEDURING 2017, JCVI HAD 10 ACTIVE RESEARCH AWARDS FROM THE DEPARTMENT OF DEFENSE (DOD). THESE AWARDS FOCUS ON THE UNDERSTANDING OF POLYMICROBIAL INFECTIONS IN WOUNDS, THE DEVELOPMENT OF SYNTHETIC GENOMIC TECHNOLOGIES FOR MANIPULATION OF CHROMOSOMES AND GENOMES AND FOR THE DEVELOPMENT OF SAFE METHODS FOR DNA ISOLATION AND ANALYSIS FROM BIOTHREAT AGENTS.FUNDED BY THE DEFENSE ADVANCES RESEARCH PROJECTS AGENCY (DARPA) BIOLOGICAL ROBUSTNESS IN COMPLEX SETTINGS (BRICS) PHASE II PROGRAM, THE JCVI IS USING INNOVATIVE RESEARCH APPROACHES TO DEVELOP A MICROBIOME FORENSIC MICROBIAL SYSTEM (FMS) THAT WILL DETECT WHETHER AND WHEN AN OBJECT ENCOUNTERED A PARTICULAR ENVIRONMENT. IN ADDITION, THE FMS SHOULD CONTAIN A SAFETY MECHANISM THAT WILL ENSURE ITS REMOVAL FROM THE ENVIRONMENT FOR CONTAINMENT. THIS FMS WILL ULTIMATELY ALLOW FOR BROAD RANGE FORENSIC APPLICATIONS OF SYNTHETIC MICROBIOMES THAT INCLUDE, BUT ARE NOT LIMITED TO, GEOSOURCING, TRACKING, AND CRIME SCENE INVESTIGATIONS.WOUND MICROBIOME PROJECT - CHRONIC WOUNDS ARE WOUNDS THAT FAIL TO HEAL AFTER 3 MONTHS UNDER STANDARD OF CARE WOUND MANAGEMENT. THE GOAL OF THIS DOD STUDY IS TO GAIN A BETTER UNDERSTANDING OF THE DIFFERENT CLASSES OF MICROBES THAT COULD BE PRESENT IN HUMAN CHRONIC WOUNDS (I.E. THE WOUND MICROBIOME), AND ASK WHETHER SPECIFIC MICROBES OR MICROBIAL COMMUNITIES ARE ASSOCIATED WITH NON-HEALING WOUNDS. NEXT GENERATION SEQUENCING WILL BE USED TO IDENTIFY AND CATALOG THE MICROBIAL SPECIES OF BACTERIA, FUNGI, AND VIRUSES THAT ARE PRESENT IN CHRONIC WOUND SPECIMENS. COMPUTATIONAL AND BIOINFORMATICS ANALYSES OF THE MICROBIAL COMMUNITY DNA SEQUENCES WILL BE CARRIED OUT TO CHARACTERIZE THE PRESENCE ANY PATHOGENIC, VIRULENCE, AND ANTIMICROBIAL RESISTANCE-RELATED GENES AND PATHWAYS. THE EVENTUAL GOAL IS TO IDENTIFY ANY PATHOGENIC SPECIES OR FEATURES THAT ARE ASSOCIATED WITH NON-HEALING WOUNDS, AND COULD BE USED AS DIAGNOSTIC AND TREATMENT TARGETS OF CHRONIC WOUNDS.FUNDED BY THE DEFENSE THREAT REDUCTION AGENCY (DTRA), THE JCVI IS INVESTIGATING AN ASPECT OF THE WELL-RECOGNIZED PUBLIC HEALTH THREAT OF ANTIBIOTIC DRUG RESISTANCE IN PATHOGENIC BACTERIA. IN ADDITION TO STANDARD BACTERIAL RESISTANCE TO ANTIBIOTICS, INFECTION CAUSING BACTERIA ARE ABLE TO ASSUME A METABOLIC STATE THAT MAKES THE BACTERIA HIGHLY TOLERANT OF MASSIVE DOSES OF ANTIBIOTICS. THIS STATE IS TERMED THE PERSISTER STATE AND ACCOUNTS FOR ANTIBIOTIC FAILURE IN PATIENTS BEING TREATED FOR INFECTIONS AND FOR THE REEMERGENCE OF AN INFECTION AFTER AN APPARENT CLEARING OF THE DISEASE BY ANTIBIOTIC TREATMENT. JCVI IS INVESTIGATING THE GENETIC/GENOMIC INFRASTRUCTURE OF THE PERSISTER STATE IN THE PUBLIC HEALTH AND BIOTHREAT BACTERIAL PATHOGEN BURKHOLDERIA PSEUDOMALLEI USING BOTH GENOME BASED TECHNOLOGIES AND TRADITIONAL MICROBIOLOGY APPROACHES WITH THE ULTIMATE GOAL OF FINDING WAYS TO ELIMINATE EVEN BACTERIA IN THE PERSISTER STATE FROM PATIENTS WITH BACTERIAL INFECTIONS.JCVI, FUNDED THROUGH THE DARPA BIOLOGICAL CONTROL PROGRAM IS APPLYING THE LESSONS LEARNED FROM MINIMIZING AND REORGANIZING A BACTERIAL GENOME TO REMODEL THE GENOME OF AN INDUSTRIALLY USEFUL, VASTLY MORE COMPLICATED EUKARYOTIC YEAST, CALLED KLUYVEROMYCES MARXIANUS. IN USING A SINGLE K. MARXIANUS CHROMOSOME AS A PLATFORM, JCVI IS DEVELOPING A GENERALIZED SET OF ALGORITHMS FOR MINIMIZATION AND DEFRAGMENTING THE GENES INTO FUNCTIONAL MODULES THAT COULD BE APPLIED TO ALL SMALL GENOME EUKARYOTES, SUCH AS YEASTS, EUKARYOTIC ALGAE, AND PARASITES. 5230875 336873 16234 OTHER PROGRAM SERVICESTHE JCVI GRANT PORTFOLIO ALSO INCLUDED SUPPORT FROM SEVERAL OTHER FEDERAL AGENCIES AND FOUNDATIONS INCLUDING:U.S. DEPARTMENT OF JUSTICE (DOJ) JCVI IS DEVELOPING A FORENSIC MICROBIOME DATABASE (FMD) THAT WILL ALLOW FOR DEVELOPING MICROBIOME TOOLS FOR POTENTIAL IN MONITORING HUMAN TRAFFICKING. AS PART OF THIS AWARD WE WILL WORK WITH 5 INTERNATIONAL COHORTS AT DIVERSE GLOBAL LOCATIONS.CENTERS FOR DISEASE CONTROL (CDC) - JCVI IS DEVELOPING A COMPREHENSIVE GENE AND PROTEIN DATABASE AND WEB RESOURCE THAT PUBLIC HEALTH EXPERTS CAN USE TO QUICKLY DETECT AND IDENTIFY ANTIBIOTIC RESISTANCE GENES AS THEY EMERGE. JCVI IS COMBINING MULTIPLE AMR GENES (ARGS) INTO A NON-REDUNDANT "LIVING" RELATIONAL DATABASE AND PUBLIC ONLINE RESOURCE THAT ALSO SERVES AS A CENTRALIZED REPOSITORY FOR IMPORTANT METADATA (E.G., BACTERIAL TAXONOMIC, GENOMIC CONTEXT, YEAR OF ISOLATE, GEOGRAPHICAL ISOLATION, ACCESSION NUMBERS, THREAT LEVEL, GENOTYPE/PHENOTYPE, ETC.) AND A TOOL FOR IN SILICO TESTING OF PCR AND RT-PCR PRIMER SETS. DEPARTMENT OF HOMELAND SECURITY (DHS) JCVI IS DEVELOPING A SEQUENCE SUBTRACTION DATABASES THAT WILL SUPPORT THE DEPARTMENT OF HOMELAND SECURITY'S CAPABILITY TO IDENTIFY NOVEL VIRUSES THAT IMPACT HUMANS AND AGRICULTURE. THE DATABASES WILL BE USED TO REMOVE HOST CELL NUCLEIC SEQUENCES FROM BIOINFORMATIC ANALYSES TO SUPPORT VIRAL DISCOVERY AND IN-DEPTH CHARACTERIZATION OF VIRUSES.THE RICHARD LOUNSBERY FOUNDATION THE JCVI TEAM IS WORKING IN COLLABORATION WITH A GROUP IN EUROPE TO DECIPHER THE GENOME OF LEONARDO DA VINCI AND HIS RELATIVES, AND ALSO USING THE MICROBIOME AS AN APPROACH TO IMPROVE ART CONSERVATION.HUMAN VACCINES PROJECT (HVP) JCVI, IN COLLABORATION WITH THE SAN DIEGO SUPERCOMPUTER CENTER, SERVES AS THE MAIN DEVELOPER OF THE CENTRAL DATA MANAGEMENT AND BIOINFORMATICS HUB FOR THE HVP, WITH DIRECT SUPPORT FROM THE HVP GENERAL FUND. THE MISSION OF THE HVP IS TO ACCELERATE THE DEVELOPMENT OF VACCINES AND IMMUNOTHERAPIES AGAINST MAJOR GLOBAL INFECTIOUS DISEASES AND CANCERS BY DECODING THE HUMAN IMMUNE SYSTEM. THE GOAL OF THE HVP BIOINFORMATICS HUB IS TO PROVIDE HIGH-AVAILABILITY, STANDARDIZED DATA AND ADVANCED ANALYTICAL CAPABILITIES TO THE HVP. JCVI IS ALSO CONTRIBUTING SINGLE CELL GENOMICS ASSAYS AND ANALYSIS EXAMINING CELLULAR RESPONSES TO HEPATITIS B VACCINATION.CALIFORNIA INSTITUTE FOR REGENERATIVE MEDICINE (CIRM) JCVI, IN COLLABORATION WITH THE UNIVERSITY OF CALIFORNIA, SANTA CRUZ, THE UNIVERSITY OF CALIFORNIA, SAN DIEGO, AND STANFORD UNIVERSITY, IS INVOLVED IN THE DEVELOPMENT OF THE MAIN DATA MANAGEMENT PORTAL FOR THE CIRM CENTER OF EXCELLENCE IN STEM CELL GENOMICS (CESCG). JCVI'S ROLE HAS BEEN TO DEVELOP A SERIES OF DATA STANDARDS TO SUPPORT THE INTEGRATION AND DISSEMINATION OF CESCG EXPERIMENTAL GENOMICS DATA, AND TO DEVELOP NOVEL STATISTICAL METHODS FOR SINGLE CELL GENOMICS DATA ANALYSIS.NASA - JCVI HAS RECEIVED FUNDING FROM NASA FOR UNDERSTANDING THE IMPACT OF SPACE TRAVEL ON THE HUMAN MICROBIOME. 5230875 336873 16234 18936437 1 1 0 0 0 0 0 1 0 0 1 0 0 0 1 1 1 0 0 0 1 1 0 0 1 0 0 1 0 1 1 0 0 0 0 0 0 0 0 0 1 1 0 0 0 1 0 0 0 0 1 38 0 1 226 1 0 0 0 0 0 0 0 0 0 0 X 9 6 1 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 CA MD X TAI NGUYEN 8582001807 4120 CAPRICORN LANE LA JOLLA CA 92037 HOROWITZREENA TRUSTEE 4.00 X 0 0 0 KAMEN DEAN TRUSTEE (THRU 4/11/17) 4.00 X 0 0 0 KNIGHT JESSIE TRUSTEE 4.00 X 0 0 0 KOWALSKI HEATHER TRUSTEE 4.00 X 0 0 0 MCGRORY JACK TRUSTEE 4.00 X 0 0 0 NELSON KAREN PRESIDENT 40.00 X X 461179 0 38844 NORRBY ERLING TRUSTEE 4.00 X 0 0 0 ROMO ALFONSO TRUSTEE 4.00 X 0 0 0 RUGGLES RUDY TRUSTEE 4.00 X 0 0 0 VENTER JOHN CRAIG CHAIRMAN & CHIEF EXEC OFFICER 40.00 X X 856975 0 11302 WALTON BILL TRUSTEE (THRU 4/11/17) 4.00 X 0 0 0 ADELSON JULIE VP, LEG. 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PART X, LINE 2: THE INSTITUTE IS A NOT-FOR-PROFIT ORGANIZATION EXEMPT FROM FEDERAL INCOME TAXES UNDER SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE. THE INSTITUTE DOES NOT BELIEVE THERE ARE ANY MATERIAL UNCERTAIN TAX POSITIONS AND ACCORDINGLY, NO PROVISION FOR INCOME TAXES HAS BEEN MADE IN THE ACCOMPANYING FINANCIAL STATEMENTS. THE INSTITUTE IS SUBJECT TO ROUTINE AUDITS BY TAXING JURISDICTIONS; HOWEVER, THERE ARE CURRENTLY NO AUDITS FOR ANY TAX PERIOD IN PROGRESS. PART XI, LINE 4B - OTHER ADJUSTMENTS: K-1 PASSTHROUGH -153. LOSS ON DISPOSAL OF INVENTORY -6,327. FUNDRAISING EXPENSES -78,136. PART XII, LINE 2D - OTHER ADJUSTMENTS: LOSS ON DISPOSAL OF INVENTORY 6,327. FUNDRAISING EXPENSES 78,136. 1 EAST ASIA AND THE PACIFIC - AUSTRALIA, BRUNEI, BURMA, CAMBODIA, 0 0 PROGRAM SERVICES RESEARCH SUBGRANTS 279687 SUB-SAHARAN AFRICA - ANGOLA, BENIN, BOTSWANA, BURKINA FASO, 0 0 PROGRAM SERVICES RESEARCH SUBGRANTS 13770 CAYMAN ISLANDS 0 0 INVESTMENTS 31717 0 0 0 0 0 0 325174 0 325174 EAST ASIA AND THE PACIFIC - AUSTRALIA, BRUNEI, BURMA, CAMBODIA, PROGRAM SERVICES 279687 WIRE SUB-SAHARAN AFRICA - ANGOLA, BENIN, BOTSWANA, BURKINA FASO, PROGRAM SERVICES 13770 WIRE 2 0 1 0 0 1 1 0 PART I, LINE 2: EACH SUBGRANT IS A PASS THROUGH GRANT FROM A FEDERAL OR NON-FEDERAL GRANT OR CONTRACT AWARDED TO J. CRAIG VENTER INSTITUTE. ALL EXPENSES ARE MONITORED AS INVOICED AT LEAST QUARTERLY, BUT IN MOST CASES MONTHLY. THE INVOICES ARE REVIEWED AND APPROVED BASED ON RECEIPT OF GOODS OR SERVICES AND AGAINST AN APPROVED BUDGET. 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CRAIG VENTER INSTITUTE. ALL EXPENSES ARE MONITORED AS INVOICED AT LEAST QUARTERLY, BUT IN MOST CASES MONTHLY. THE INVOICES ARE REVIEWED AND APPROVED BASED ON RECEIPT OF GOODS OR SERVICES AND AGAINST AN APPROVED BUDGET. X X X 1 1 X X X X 1 0 0 0 0 0 0 1 0 NELSON KAREN PRESIDENT 456977 0 0 0 4202 0 12137 0 26707 0 500023 0 0 0 VENTER JOHN CRAIG CHAIRMAN & CHIEF EXEC OFFICER 840563 0 0 0 16412 0 10402 0 900 0 868277 0 0 0 ADELSON JULIE VP, LEG. AFFRS/GENERAL COUNSEL 195626 0 0 0 12708 0 9867 0 2550 0 220751 0 0 0 DEBERG NICOLE COO (THRU 11/28/17) 325346 0 0 0 82602 0 17310 0 8039 0 433297 0 0 0 FRIEDMAN ROBERT M VP FOR POLICY & UNIV. 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SCHEDULE J, PART I, LINE 1A; FIRST-CLASS OR CHARTER TRAVEL - THE ORGANIZATION PROVIDES THE CEO FIRST CLASS AND CHARTER TRAVEL FOR BUSINESS PURPOSES. NO PART OF THIS BENEFIT IS TREATED AS TAXABLE COMPENSATION. SCHEDULE J, PART I, LINE 1A; PERSONAL SERVICES - THE ORGANIZATION PROVIDES THE CEO SERVICES OF BODYGUARDS WHEN HE TRAVELS. NO PART OF THIS BENEFIT IS TREATED AS TAXABLE COMPENSATION. PART I, LINE 4A NICOLE DEBERG RECEIVED SEVERANCE IN THE AMOUNT OF $78,750. PART I, LINE 7 THE INSTITUTE PROVIDES SERVICE AWARDS FOR ITS EMPLOYEES FOR FIVE, TEN, FIFTEEN AND TWENTY YEARS OF SERVICE. A CA MUNICIPAL FINANCE AUTHORTIY 201563466 2016-03-22 29152000 REFUND PRIOR ISSUE 0 0 0 A 29152000 549311 1 0 1 1 A 0 0 0 0 1 0 1 A 0 1 0 0 0 0 0 0 1 A 1 SCHEDULE K - TAX EXEMPT BONDS PROJECT COMPLETED IN NOVEMBER 2013. 2011 BOND WAS REFINANCED IN 2016. HEATHER KOWALSKI COMMUNICATIONS LLC SEE PART V 120000 PUBLIC RELATIONS SERVICES 0 SCHEDULE L, PART IV (A) NAME OF PERSON: HEATHER KOWALSKI COMMUNICATIONS LLC(B) RELATIONSHIP BETWEEN INTERESTED PERSON AND ORGANIZATION: ENTITY SET UP IN THE NAME OF HEATHER KOWALSKI, SPOUSE OF FOUNDER, BOARD MEMBER SINCE 2014 (C) AMOUNT OF TRANSACTION $ 120,000(D) DESCRIPTION OF TRANSACTION: PUBLIC RELATIONS SERVICES X 2 334480 FMV 0 0 1 0 FORM 990, PART VI, SECTION A, LINE 2 BOARD MEMBERS HEATHER KOWALSKI AND J. CRAIG VENTER HAVE A FAMILY RELATIONSHIP. FORM 990, PART VI, SECTION B, LINE 11B THE FORM 990 IS REVIEWED BY MANAGEMENT. A COMPLETE COPY OF THE FORM 990 AND SUPPORTING SCHEDULES WAS PROVIDED TO THE FULL BOARD FOR REVIEW PRIOR TO BEING FILED. FORM 990, PART VI, SECTION B, LINE 12C JCVI MONITORS COMPLIANCE OF ITS CONFLICT OF INTEREST POLICY THROUGH AN ANNUAL SOLICITATION OF CONFLICT OF INTEREST STATEMENTS FROM TRUSTEES, OFFICERS, AND EMPLOYEES. IF A PERSON HAS A CONFLICT WITH RESPECT TO A TRANSACTION, SUCH PERSON IS NOT ALLOWED TO VOTE. FORM 990, PART VI, SECTION B, LINE 15 JCVI USES AN OUTSIDE COMPENSATION CONSULTANT, TO PROVIDE A LIST OF COMPARABLE SALARIES FOR THE CEO AND OFFICERS THESE ARE REVIEWED BY THE JCVI COMPENSATION COMMITTEE AND CEO BEFORE A FINAL DETERMINATION IS MADE. THIS PROCESS WAS DOCUMENTED AND LAST DONE IN JUNE 2016. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION'S FINANCIAL STATEMENTS, GOVERNING DOCUMENTS, AND CONFLICT OF INTEREST POLICY ARE MADE AVAILABLE TO THE PUBLIC UPON REQUEST. FORM 990, PART XI, LINE 9: K-1 PASSTHROUGH 153. OCEAN SOLUTION LLC 4120 CAPRICORN LANE LA JOLLA CA 92037 260145075 DEVELOPMENT DE 0 1269265 JCVI SORCERER II LLC 4120 CAPRICORN LANE LA JOLLA CA 92037 562370157 RESEARCH RI 0 1709985 JCVI 1