2018-11-14T16:06:00-06:00 2017-12-31 861065772 DELOITTE TAX LLP 50 SOUTH SIXTH STREET MINNEAPOLIS MN 55402 990 2017-01-01 811669175 CHAN ZUCKERBERG BIOHUB INC CHAN 6282003246 499 ILLINOIS ST SAN FRANCISCO CA 94158 VICTOR COLUNGA CFO 6282003246 2018-11-14 1 ANNE FULTON P00941863 6123974000 167.219.0.140 2018-11-14 15:17:11 CS P DBFC69D4407EB49F10916D270E60D798182E6690 B252FF5B9BBCFA038C79E434122BFD2571701D66 2017 2019-02-21 02:37:17Z GAJUS WORTHINGTON 499 ILLINOIS ST SAN FRANCISCO CA 94158 9493904 0 X WWW.CZBIOHUB.ORG X 2016 CA CONDUCT CUTTING EDGE MEDICAL RESEARCH. 7 3 64 5 0 0 580723074 8700089 0 403498 56550 390317 0 0 580779624 9493904 4800000 15100000 0 0 314189 5076068 0 0 0 1855638 13658972 6969827 33835040 573809797 -24341136 581780417 562469286 4720620 9750625 577059797 552718661 X ALLEVIATING HUMAN SUFFERING THROUGH ITS MISSION TO CURE, MANAGE, AND PREVENT ALL DISEASES BY THE END OF THE 21ST CENTURY. 0 0 28770053 15100000 403498 AS A NEWLY FORMED MEDICAL RESEARCH ORGANIZATION, THE PLANNED RESEARCH OF CHAN ZUCKERBERG BIOHUB, INC. (THE "BIOHUB"), WILL FOCUS ON SEVERAL LARGE-SCALE SCIENTIFIC ELEMENTS WITH A MULTI-YEAR LIFETIME. THESE WILL TAKE THE FOLLOWING FORMS:INTERNAL PROJECTS FOCUSING ON BASIC SCIENCE AND SOME ON CLINICAL RESEARCH. IN ADDITION, THE BIOHUB EXPECTS TO CONDUCT A NUMBER OF SMALLER RESEARCH PROGRAMS, THE MOST PROMISING OF WHICH COULD FORM THE BASIS FOR LARGE-SCALE SCIENTIFIC PROGRAMS THAT THE BIOHUB WILL FOCUS ON IN FUTURE YEARS. TWO OF THE LARGE-SCALE PROJECTS WILL BE THE FOLLOWING: 1. THE CELL ATLAS PROGRAM WILL CONSTITUTE A MASSIVE HUMAN CELL TYPE, CELL STATE AND GENETIC INTERACTION MAP SEVERAL ORDERS OF MAGNITUDE LARGER AND HIGHER DIMENSION THAN ALL PRECEDING EFFORTS IN MODEL ORGANISMS, AND WILL INITIALLY FOCUS ON CANCER, NEUROLOGICAL AND CARDIOVASCULAR FUNCTIONS. 2. THE INFECTIOUS DISEASE PROGRAM SERVICE ACCOMPLISHMENTS: DISEASE PROJECT WILL UTILIZE A MULTI-PRONGED APPROACH TO COMBAT INFECTIOUS DISEASES, AND BOTH DRUG DISCOVERY AND VACCINE DESIGN EFFORTS. IN ADDITION, THE BIOHUB WILL FUND COMPLEMENTARY AND COOPERATIVE RESEARCH PROJECTS THROUGH THE CHAN ZUCKERBERG INVESTIGATORS PROGRAM AND AFFILIATE GIFT PROGRAM. THE BIOHUB WILL ALSO SERVE AS A SCIENTIFIC RESOURCE HUB BY PROVIDING SPACE, EQUIPMENT AND OTHER SUPPORT FOR CHAN ZUCKERBERG INVESTIGATORS AND OTHER COMMUNITY MEMBERS. IT WILL ALSO GENERALLY BE A CENTER FOR EXCHANGE OF IDEAS FOR THE EXTENDED SCIENTIFIC COMMUNITY. 28770053 1 1 0 0 0 0 0 0 0 0 1 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 1 0 0 1 1 0 0 0 0 1 0 0 0 1 84 0 1 64 1 0 0 0 0 0 0 0 0 0 0 X 7 3 1 1 0 0 0 1 1 1 1 0 0 1 1 0 1 1 0 1 1 1 0 CA X VICTOR COLUNGA CFO 6282003246 499 ILLINOIS ST SAN FRANCISCO CA 94158 CORI BARGMANN DIRECTOR 5.00 X 0 0 0 DR JOHN HENNESSY DIRECTOR 5.00 X 0 0 0 DR JOSEPH DERISI CO-CHIEF EXECUTIVE 40.00 X X 365940 0 33552 DR PRISCILLA CHAN DIRECTOR 5.00 X 0 0 0 DR STEPHEN QUAKE CO-CHIEF EXECUTIVE 40.00 X X 365940 0 33552 MARK ZUCKERBERG DIRECTOR 5.00 X 0 0 0 REID HOFFMAN DIRECTOR 5.00 X 0 0 0 RAKESH MEHTA TREASURER 5.00 X 0 0 0 TOM VAN LOBEN SELS END 12717 SECRETARY 5.00 X 0 0 0 BARBARA KOSACZ START 12717 SECRETARY 5.00 X 0 0 0 GAJUS WORTHINGTON CHIEF OPERATING OFFICER 40.00 X 297281 0 12992 JIM KARKANIAS VP DATA SCIENCES & IT INFRASTRUCTURE 40.00 X 276073 0 34940 ANDREW MAY SENIOR DIRECTOR, GENOME ENGINEERING 40.00 X 267425 0 17658 RAFAEL GOMEZ-SJOBERG DIRECTOR, BIOENGINEERING 40.00 X 202235 0 23320 AMY KISTLER GROUP LEADER (SENIOR SCIENTIST) 40.00 X 166181 0 26252 NORMA NEFF SENIOR FELLOW 40.00 X 195278 0 15402 2136353 0 197668 13 0 1 0 COOLEY LLP 101 CALIFORNIA STREET 5TH FLOOR SAN FRANCISCO CA 94111 LEGAL CONSULTING 270620 FLG PARTNERS LLC 228 HAMILTON AVENUE 3RD FLOOR PALO ALTO CA 94301 FINANCE CONSULTING 256213 APERCEN PARTNERS LLC 314 LYTTON AVENUE 200 PALO ALTO CA 94301 FINANCE CONSULTING 223290 WIDE CENTER ADVISORS LLC PO BOX 20713 OAKLAND CA 94620 OPERATIONS CONSULTANT 195050 ARNOLD & PORTER KAYE SCHOLER LLP 601 MASSACHUSETTS AVENUE NW WASHINGTON DC 20001 LEGAL CONSULTING 131339 7 8700089 656650 8700089 COLLABORATION PROGRAM 541700 403498 403498 403498 390317 390317 9493904 403498 0 390317 15100000 15100000 1109257 1109257 3169840 2952859 216981 150555 63173 87382 343590 118734 224856 302826 240223 62603 422738 11060 411678 807210 807210 1525462 425295 1100167 336981 336981 3010141 2902769 107372 551725 445292 106433 2985249 2637591 347658 113026 56400 56626 30777 30077 700 872411 856918 15493 38298 31749 6549 LAB SUPPLIES 2843979 2843760 219 MEALS AND ENTERTAINMENT 120975 54153 66822 33835040 28770053 5064987 0 1742450 4601804 57087550 83377771 521973074 464127355 175973 93827 8012883 872410 977343 7140473 0 2952083 581780417 562469286 1080620 2582738 3640000 7167887 4720620 9750625 X 55086723 85639223 521973074 467079438 577059797 552718661 581780417 562469286 -24341136 0 X 0 1 X 1 0 X AFFILIATED HOSPITALS OF STANFORD STANFORD CA AFFILIATED HOSPITALS OF UCSF SAN FRANCISCO CA SCHEDULE A THE BIOHUB IS IN THE PROCESS OF LAUNCHING ITS RESEARCH ACTIVITIES. IT IS A NEWLY-CREATED ORGANIZATION AND BELIEVES IT WILL BE CONSIDERED TO BE CONTINUOUSLY ENGAGED IN THE ACTIVE CONDUCT OF MEDICAL RESEARCH IN CONJUNCTION WITH A HOSPITAL AND IT REASONABLY EXPECTS TO SATISFY THE ASSET TEST OR ENDOWMENT TEST BY THE END OF ITS ORGANIZATIONAL PERIOD OF UP TO THREE YEARS. 205667 13613 192054 7807216 858797 6948419 7140473 LIABILITY FOR INVESTIGATOR AWARDS 7167887 7167887 X 9493904 0 9493904 0 9493904 33835040 0 33835040 0 33835040 PART X, LINE 2: THE BIOHUB IS EXEMPT FROM INCOME TAXES UNDER SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE AS A MEDICAL RESEARCH ORGANIZATION OPERATED IN CONJUNCTION WITH A HOSPITAL AND SECTION 23701D OF THE CALIFORNIA REVENUE AND TAXATION CODE. THE BIOHUB HAS NO UNRECOGNIZED TAX BENEFITS OR LIABILITIES AS OF DECEMBER 31, 2017. 1 STANFORD 3145 PORTER DRIVE PALO ALTO CA 94304 941156365 501(C)(3) 6650000 SCIENTIFIC AND MEDICAL RESEARCH UCSF UCSF PO BOX 0248 SAN FRANCISCO CA 94143 946036493 501(C)(3) 5600000 SCIENTIFIC AND MEDICAL RESEARCH UC BERKELEY 2195 HEARST AVE RM 120 MC 1104 BERKELEY CA 94720 946002123 501(C)(3) 2850000 SCIENTIFIC AND MEDICAL RESEARCH 3 PART I, LINE 2: THE BIOHUB WILL OBLIGATE THE USE OF THE GIFT FUNDS ONLY FOR THE PURPOSE FOR WHICH THE BIOHUB MAKES THE AWARD. THE BIOHUB WILL REQUIRE PERIODIC WRITTEN REPORTS CONCERNING THE USE OF THE GIFT AS APPROPRIATE AND RETAIN FOR THE BIOHUB THE RIGHT TO WITHHOLD OR RECOVER FUND IN CASES OF MISUSE AS APPROPRIATE. FROM TIME TO TIME, THE BIOHUB WILL MAKE DISCRETIONARY GIFTS TO 501(C)(3) ORGANIZATIONS WITHOUT THE NEED FOR A WRITTEN PROPOSAL. X X X 0 0 0 0 0 0 0 1 0 DR JOSEPH DERISI CO-CHIEF EXECUTIVE 365940 0 0 0 0 0 6552 0 27000 0 399492 0 0 0 DR STEPHEN QUAKE CO-CHIEF EXECUTIVE 365940 0 0 0 0 0 6552 0 27000 0 399492 0 0 0 GAJUS WORTHINGTON CHIEF OPERATING OFFICER 211521 0 85760 0 0 0 6811 0 6181 0 310273 0 0 0 JIM KARKANIAS VP DATA SCIENCES & IT INFRASTRUCTURE 216313 0 59760 0 0 0 6858 0 28082 0 311013 0 0 0 ANDREW MAY SENIOR DIRECTOR, GENOME ENGINEERING 210505 0 56920 0 0 0 9000 0 8658 0 285083 0 0 0 RAFAEL GOMEZ-SJOBERG DIRECTOR, BIOENGINEERING 167475 0 34760 0 0 0 5109 0 18211 0 225555 0 0 0 AMY KISTLER GROUP LEADER (SENIOR SCIENTIST) 143801 0 22380 0 0 0 7994 0 18258 0 192433 0 0 0 NORMA NEFF SENIOR FELLOW 158588 0 36690 0 0 0 9509 0 5893 0 210680 0 0 0 PART I, LINE 7 INCENTIVE COMPENSATION WAS PROVIDED TO CERTAIN PERSONS LISTED ON PART VII OF THE FORM 990. INCENTIVE COMPENSATION WAS PAID BASED ON A FIXED PERCENTAGE OF BASE COMPENSATION, PLUS AN ADDITIONAL DISCRETIONARY PERCENTAGE SUBJECT TO BOARD APPROVAL. DR STEPHEN QUAKE CO-CHIEF EXECUTIVE & BOARD MEMBER OF ORGANIZATION 2000000 AWARD TO CONDUCT RESEARCH AWARD PROVIDED TO STANFORD UNIVERSITY TO SUPPORT RESEARCH LAB OF DR. QUAKE DR JOSEPH DERISI CO-CHIEF EXECUTIVE & BOARD MEMBER OF ORGANIZATION 2000000 AWARD TO CONDUCT RESEARCH AWARD PROVIDED TO UCSF TO SUPPORT RESEARCH LAB OF DR. DERISI CHAN ZUCKERBERG INITIATIVE ENTITY OWNED BY MARK ZUCKERBERG, DIRECTOR 201029 INVITEE FEES PAID FROM CZI TO BIOHUB 0 APERCEN PARTNERS LLC ENTITY MORE THAN 35% OWNED BY TOM VAN LOBEN SELS, SECRETARY 223290 FINANCE CONSULTING 0 X EQUIPMENT 1 288513 FAIR MARKET VALUE X LEASEHOLD IMPROVEMENTS 1 193968 FAIR MARKET VALUE X FURNITURE & EQUIPMENT 1 174169 FAIR MARKET VALUE 0 0 0 0 PART I, COLUMN (B): COLUMN (B) REPRESENTS THE NUMBER OF CONTRIBUTIONS. FORM 990, PART VI, SECTION A, LINE 2 DR. CHAN (DIRECTOR) AND MR. ZUCKERBERG (DIRECTOR) HAVE A FAMILY RELATIONSHIP. APERCEN PARTNERS LLC, IN WHICH TOM VAN LOBEN SELS (SECRETARY) HAS MORE THAN A 35% OWNERSHIP INTEREST, HAS A BUSINESS RELATIONSHIP WITH DR. CHAN, MR. ZUCKERBERG, AND REID HOFFMAN. CORI BARGMANN AND MR. ZUCKERBERG HAVE A BUSINESS RELATIONSHIP. FORM 990, PART VI, SECTION A, LINE 3 TWO UNRELATED PARTIES, WIDE CENTER ADVISORS, LLC AND FLG PARTNERS, LLC, PROVIDE OPERATIONAL CONSULTING SERVICES TO THE BIOHUB, INCLUDING, BUT NOT LIMITED TO, SUPPORT OF THE ORGANIZATION'S FINANCIAL, BUDGETING, STAFFING, FACILITIES, AND PROFESSIONAL SERVICES CAPACITIES. FORM 990, PART VI, SECTION A, LINE 7A THE CHAN ZUCKERBERG INITIATIVE, LLC DESIGNATES TWO BOARD OF DIRECTORS (DESIGNATED DIRECTORS). SUCH DESIGNATED DIRECTORS APPROVE THE APPOINTING, ELECTING, OR REMOVING OF ANY DIRECTOR OF THE ORGANIZATION INCLUDING THE FILLING OF ANY VACANCY OF THE BOARD. FORM 990, PART VI, SECTION A, LINE 7B GOVERNANCE DECISIONS ARE SUBJECT TO APPROVAL BY THE TWO DESIGNATED DIRECTORS INCLUDING: -CHANGING THE NATURE OR SCOPE OF THE MISSION. -CHANGING, SELLING OR LICENSING THE NAME OF THE CORPORATION. -APPROVING OR PERMITTING THE USE OF OTHER EXPLOITATION OF THE NAME OF THE CORPORATION BY ANY PARTY, OTHER THAN THE DESIGNATOR, ANY AFFILIATE OR AFFILIATED ENTITY OF THE DESIGNATOR AND, SOLELY IN CONNECTION WITH THE CORPORATION'S ACTIVITIES IN FURTHERANCE OF THE MISSION. -APPOINTING, ELECTING OR REMOVING ANY DIRECTOR OF THE CORPORATION AND FILLING OF ANY VACANCY OF THE BOARD. -INCREASING OR DECREASING THE NUMBER OF DIRECTOR SEATS ON THE BOARD. -APPOINTING, ELECTING OR REMOVING THE CHAIRPERSON -ACCEPTING CONTRIBUTIONS FROM ANY PARTY OTHER THAN FROM THE DESIGNATOR, ANY AFFILIATE OR AFFILIATED ENTITY OF THE DESIGNATOR, OR ANY DONOR ADVISED FUND IN WHICH THE DESIGNATION OR AFFILIATE HAVE ADVISORY PRIVILEGES. OTHER PARTY FUNDING CAN BE ACCEPTED IF THE DESIGNATOR FUNDING SOURCE HAS A MATERIAL BREACH AND ADDITIONAL FUNDING IS NEEDED. -APPROVAL OR EFFECTING OF A MATERIAL SALE OF ASSETS OR MERGER OF THE ORGANIZATION OR CONVERSION INTO ANOTHER FORM OF ENTITY. -APPROVAL OF ACTION CAUSING CHANGE FROM EXEMPT STATUS UNDER 501(A) OF THE CODE. -APPROVAL FOR COMMENCING BANKRUPTCY, INSOLVENCY OR RELIEF OF DEBTORS. -APPROVAL, PERMITTING OR EFFECTING ANY TRANSACTION TO LIQUIDATE, WIND UP OR DISSOLVE THE CORPORATION. -APPROVAL FOR CHANGE TO ORGANIZATION DOCUMENTS. FORM 990, PART VI, SECTION B, LINE 11B THE FORM 990 IS PREPARED BY OUR TAX CONSULTANTS. THE DRAFT IS REVIEWED BY THE CFO OF THE ORGANIZATION. THE FORM 990 IS THEN MADE AVAILABLE TO THE BOARD PRIOR TO THE 990 BEING FILED. FORM 990, PART VI, SECTION B, LINE 12C OFFICERS AND DIRECTORS SIGN A CONFLICT OF INTEREST AFFIDAVIT UPON APPOINTMENT. IN CONNECTION WITH ANY ACTUAL OR POSSIBLE CONFLICT OF INTEREST, A COVERED PERSON MUST IMMEDIATELY DISCLOSE TO THE BOARD OR COMMITTEE THE EXISTENCE AND NATURE OF HIS OR HER FINANCIAL INTEREST OR ANY DISCLOSABLE RELATIONSHIPS. AFTER A COVERED PERSON HAS DISCLOSED THE EXISTENCE OF A FINANCIAL INTEREST, THE BOARD OR COMMITTEE SHALL DETERMINE IF A CONFLICT OF INTEREST EXISTS. IF A TRANSACTION ARISES WHERE THERE IS A CONFLICT OF INTEREST, THE PERSON WITH SUCH CONFLICT IS NOT ALLOWED TO VOTE ON THE TRANSACTION. FORM 990, PART VI, SECTION B, LINE 15 THE BOARD OF DIRECTORS AND EXECUTIVE COMMITTEE OF THE BOARD REVIEW AND APPROVE THE COMPENSATION OF THE ORGANIZATION'S CO-CHIEF EXECUTIVES AND COO. THE PROCESS INCLUDES A REVIEW OF THE COMPENSATION AGAINST CURRENT COMPARABILITY DATA (SURVEY OR STUDY) PREPARED BY AN INDEPENDENT COMPENSATION CONSULTANT. THE PROCESS IS DOCUMENTED AND WAS LAST COMPLETED SEPTEMBER 2016. FORM 990, PART VI, SECTION C, LINE 19 THE BIOHUB'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS WILL BE FURNISHED TO THE PUBLIC UPON REQUEST. FORM 990, PART VI, SECTION B, LINE 16B BIOHUB HAS EXECUTED CERTAIN WRITTEN COLLABORATION AGREEMENTS IN FURTHERANCE OF ITS EXEMPT MISSION. SUCH CONTRACTS ARE EXECUTED ON TERMS THAT ARE AT ARM'S LENGTH OR MORE FAVORABLE TO BIOHUB. TANGIBLE PROPERTY ELECTION FOOTNOTE SECTION 1.263(A)-1(F) DE MINIMIS SAFE HARBOR ELECTION TAXPAYER IS MAKING THE DE MINIMIS SAFE HARBOR ELECTION UNDER TREAS. REG. 1.263(A)-1(F) FOR ALL ELIGIBLE AMOUNTS PAID OR INCURRED DURING THE TAXABLE YEAR. SECTION 1.263(A)-3(N) CAPITALIZATION ELECTION TAXPAYER HEREBY ELECTS TO CAPITALIZE REPAIR AND MAINTENANCE COSTS UNDER TREAS. REG. 1.263(A)-3(N). THE COSTS WERE INCURRED DURING THE TAXABLE YEAR IN THE ELECTING TAXPAYER'S TRADE OR BUSINESS AND THE ELECTING TAXPAYER TREATS SUCH COSTS AS CAPITAL EXPENDITURES ON ITS BOOKS AND RECORDS. CHAN ZUCKERBERG ADVOCACY 314 LYTTON AVENUE SUITE 200 PALO ALTO CA 94301 813742328 SOCIAL WELFARE CA 501(C)(4) N/A N/A 0 CHAN ZUCKERBERG FOUNDATION 314 LYTTON AVENUE SUITE 200 PALO ALTO CA 94301 455002209 GRANTMAKING CA 501(C)(3) PF N/A 0 THE PRIMARY SCHOOL 314 LYTTON AVENUE SUITE 200 PALO ALTO CA 94301 364858582 SOCIAL WELFARE CA 501(C)(4) N/A N/A 0 THE PRIMARY SCHOOL - EAST PALO ALTO 314 LYTTON AVENUE SUITE 200 PALO ALTO CA 94301 473334579 EDUCATION CA 501(C)(3) LINE 2 N/A 0 OPENNESS FOUNDATION 314 LYTTON AVENUE SUITE 200 PALO ALTO CA 94301 270889149 GRANTMAKING CA 501(C)(3) PF N/A 0 FACEBOOK INC 1601 WILLOW ROAD MENLO PARK CA 94025 SOCIAL MEDIA SERVICE COMPANY DE N/A C 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0