2019-08-14T10:36:02-05:00 2018-09-30 861065772 Deloitte Tax LLP 250 East Fifth Street Cincinnati OH 45202 990 2017-10-01 453682796 California Institute for BioMedical Research CALI 8582421029 11119 N Torrey Pines Rd STE 100 La Jolla CA 92037 Peter G Schultz Treasurer 8582421029 2019-08-13 1 Rebecca Lyons P01487105 5137847100 167.219.88.226 2019-08-13 16:55:11 ED P 8121CA463AABFA4EFE5158FD2073B628CA1C8F6D 76FF2A6BB2396675DA7FC3BECCB7F23E28595D91 2017 2019-02-21 02:37:17Z X Peter G Schultz PhD 11119 N Torrey Pines Rd STE 100 La Jolla CA 92037 98797059 0 X www.calibr.org X 2011 CA The California Institute for Biomedical Research (CALIBR) accelerates the translation of basic biomedical research to new medicines for unmet medical needs. X 19 17 157 0 0 0 0 22438747 4064261 63285520 7430 167492 21284 12905300 4092975 98797059 5858 124436 0 0 820098 9952959 0 0 0 3527353 30300341 4353309 40377736 -260334 58419323 23497334 0 8188506 0 15308828 0 X Our mission is to build a unique institute that bridges basic research and drug discovery, and that attracts the best and brightest scientists, physicians and students to work together synergistically to find cures for neglected human diseases. The California Institute for Biomedical Research (CALIBR) is a biomedical research organization located in San Diego, California. CALIBR bridges the gap between basic biomedical research and the clinical application of research discoveries to human disease. CALIBR commits substantially all of its resources to biomedical research activities. CALIBR's research and work will catalyze the translation of discoveries by scientists at other San Diego research institutes, as well as other major research institutes throughout the world, into potential new therapies for many life threatening and debilitating diseases. These diseases include orphan diseases, degenerative diseases of aging, cancer, autoimmune diseases, and infectious diseases. 0 0 35427676 124436 74640868 Research grants and contracts are received from public and private institutions and are used to conduct biomedical research. In the current fiscal year, CALIBR conducted research through a private collaboration agreement on autoimmune and inflammatory diseases, cancer biology, cardiovascular metabolic diseases and neurobiology. In addition, it conducted research for the treatment of spinal muscular atrophy, juvenile diabetes, tb drug development, osteoarthritis, cryptosporidiosis and malaria. 35427676 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 1 1 0 1 0 0 1 0 0 0 1 54 0 1 157 1 0 0 0 0 0 0 0 0 X 19 17 1 0 1 0 1 1 1 1 1 0 0 1 1 1 1 1 1 1 1 0 CA X Kelly San George 8582421000 11119 N Torrey Pines Rd STE 100 La Jolla CA 92037 Peter G Schultz CEO/President & Chair 40.00 40.00 X X 285562 368514 67321 Herbert Boyer Board Member 1.00 1.00 X 0 0 0 Ronald Burkle Board Member 1.00 1.00 X 0 0 0 Gerald Chan Start 32918 Board Member 1.00 1.00 X 0 0 0 John D Diekman Start 32918 Board Member 1.00 1.00 X 0 0 0 Mark Edwards Board Member 1.00 1.00 X 0 0 0 Peter C Farrell PHD DSc Board Member (Start 3/28/18) 1.00 1.00 X 0 0 0 Isy Goldwasser Board Member 1.00 1.00 X 0 0 0 Benedict Gross Start 92818 Board Member 1.00 0.00 X 0 0 0 William R Hearst III Board Member (Start 3/29/18) 1.00 1.00 X 0 0 0 Jeffery Kelly Start 92818 Board Member 1.00 40.00 X 0 372693 66417 Sherry Lansing Start 5718 Board Member 1.00 1.00 X 0 0 0 Ge Li Start 32918 Board Member 1.00 1.00 X 0 0 0 Claudia S Luttrell Board Member (Start 3/29/18) 1.00 1.00 X 0 0 0 Joel S Marcus Start 32918 Board Member 1.00 1.00 X 0 0 0 John Martin Start 5718 Board Member 1.00 1.00 X 0 0 0 Mark Pearson Start 32818 Board Member 1.00 1.00 X 0 0 0 Bernard Saint-Donat PHD Board Member (Start 3/28/18) 1.00 1.00 X 0 0 0 Paul R Schimmel End 92818 Board Member 1.00 40.00 X 0 44300 21185 Christopher T Walsh Board Member 1.00 1.00 X 0 0 0 Douglas A Bingham Secretary/EVP of Scripps Florida 1.00 40.00 X 0 301788 60656 Kelly San George End 32818 CFO, CALIBR/Treasurer 40.00 0.00 X 67786 0 1443 Jared M Machado CFO,Scripps/Treasurer 1.00 40.00 X 0 273430 65619 Matthew S Tremblay COO,CALIBR/Secretary (End 3/28/18) 40.00 40.00 X 216426 165056 7823 Tamara L Barnas Asst Secretary 0.00 40.00 X 0 91344 23393 Leonardo Sahelijo VP, Translational Medicine 40.00 0.00 X 365208 0 22775 Vadim Klyushnichenko VP of Pharm. Dev & Quality 40.00 0.00 X 314321 0 28151 Arnab K Chatterjee VP, Medicinal Chemistry 40.00 0.00 X 234592 0 2478 Jing Li VP, Program Management 40.00 0.00 X 216149 0 5431 John A Wisler VP, Toxicology and Pharmacokinetics 40.00 0.00 X 225104 0 20765 1925148 1617125 393457 7 0 1 0 Alexandria 385 E Colorado Blvd Ste 299 Pasadena CA 91101 Rental Services 1418100 Wilson Sonsini Goodrich & Rosati PO Box 742866 Los Angeles CA 90074 Legal Services 614306 Cooley 101 California Street 5th Floor San Francisco CA 94111 Legal Services 396656 RSM US LLP 331 West 3rd Street Suite 200E Davenport IA 52801 Accounting 184500 Ingenium 2280 Micro Place Escondido CA 92029 Waste Removal 156970 9 698146 21740601 300226 22438747 Medical Research 541700 63285520 63285520 63285520 167492 167492 25422 25422 1524530 0 1524530 1524530 1524530 Inherent Contribution 900099 11354634 11354634 Other Revenue 900099 714 714 11355348 98797059 74640868 0 1717444 124436 124436 569774 569774 7947634 6874333 1073301 182794 160570 22224 664291 652248 12043 588466 491256 97210 490855 352003 138852 2247041 1082574 1164467 145194 145194 88427 5394 83033 506643 380780 125863 5458192 4552542 905650 98704 83736 14968 11658 9336 2322 5518 5518 1722749 1703708 19041 166447 29974 136473 Outsourced Research Svc 14527562 14527562 Lab Supplies 3314559 3314559 Service Agreements 706931 684387 22544 Taxes 102889 4230 98659 706972 394048 312924 40377736 35427676 4950060 0 300 0 10293984 0 3905233 0 0 0 0 0 0 1411801 0 0 5578221 0 0 448877 0 0 1816531 0 42387 0 23497334 0 2918940 3928936 1340630 8188506 0 X 15308828 0 15308828 0 23497334 0 X 58419323 -73728151 X 0 1 X 1 1 1 X UC San Diego Medical Center San Diego CA Scripps Memorial Hospital La Jolla La Jolla CA 1 The Scripps Research Institute 10550 N Torrey Pines Rd STE 100 La Jolla CA 92037 330435954 501(C)(3) 124436 N/A N/A Support for Postdoctoral Fellows 1 0 Part I, Line 2: Funding was provided to The Scripps Research Institute to support a number of postdoctoral fellowships for research and lab support activities. Since these fellows are working at one of the hospitals operating in conjunction with the Institute, there is continuous monitoring of the use of the support provided. X X X X 0 0 0 0 0 0 0 0 0 Peter G Schultz CEO/President & Chair 285562 334811 0 0 0 33703 0 54000 0 13321 285562 435835 0 0 Jeffery Kelly Start 92818 Board Member 0 342006 0 0 0 30687 0 54000 0 12417 0 439110 0 0 Douglas A Bingham Secretary/EVP of Scripps Florida 0 239225 0 25002 0 37561 0 48710 0 11946 0 362444 0 0 Jared M Machado CFO,Scripps/Treasurer 0 243718 0 18751 0 10961 0 48942 0 16677 0 339049 0 0 Matthew S Tremblay COO,CALIBR/Secretary (End 3/28/18) 124426 132556 92000 32500 0 0 6492 1250 0 81 222918 166387 0 0 Leonardo Sahelijo VP, Translational Medicine 290208 0 75000 0 0 0 8100 0 14675 0 387983 0 0 0 Vadim Klyushnichenko VP of Pharm. Dev & Quality 265571 0 48750 0 0 0 8100 0 20051 0 342472 0 0 0 Arnab K Chatterjee VP, Medicinal Chemistry 190592 0 44000 0 0 0 2478 0 0 0 237070 0 0 0 Jing Li VP, Program Management 176149 0 40000 0 0 0 5431 0 0 0 221580 0 0 0 John A Wisler VP, Toxicology and Pharmacokinetics 210771 0 14333 0 0 0 6812 0 13953 0 245869 0 0 0 Joel S Marcus Member of the Board - California Institute for BioMedical Research 1705648 California Institute for BioMedical Research (CALIBR) leases office and laboratory space building from Alexandria Real Estate (ARE). Joel S. Marcus is the Executive Chairman & Founder of ARE. Mr. Marcus was appointed to CALIBR'S Board as of March 2018. Lease commenced in March 2012, at which time, Mr. Marcus was not a member of CALIBR'S Board. 0 Ge Li Member of the Board - California Institute for BioMedical Research 933294 California Institute for BioMedical Research (CALIBR) has contracts with outside parties for outsourced research services. Ge Li is the Chairman and Chief Executive Officer at Wuxi Companies which is one of the contracted parties to provide outsourced research servces. CALIBR began working with Wuxi in 2013, at which time Mr. Li was not a member of CALIBR's Board. Wuxi Companies and CALIBR do not share revenues. 0 X 1 300226 Cost or Selling Price 0 0 0 Part I, Column (b): Securities - Publicly traded - No. of contributions Net Assets 2018-09-30 73728151 Book Value 330435954 The Scripps Research Institute 10550 North Torrey Pines Road La Jolla CA 92037 501(c)(3) 1 1 0 0 1 1 1 1 0 Schedule N, Part I, Line 2a: Prior to dissolution, CAILBR became a related organization of Scripps Research Institute. CALIBR and Scripps Research Institute became related by virtue of complete board overlap. CALIBR later dissolved and became a division of Scripps Research Institute. Therefore, all CALIBR Board Members are also Board Members of Scripps Research Institute. Schedule N, Part I, Line 2b: CALIBR became a division of Scripps Research Institute. Therefore, all CALIBR employees are now employees of Scripps Research Institute. Form 990, Part VI, Section A, line 2 CEO and Board Chair Peter Schultz serves on a number of other corporate boards with Board Member Isy Goldwasser. Form 990, Part VI, Section A, line 4 CALIBR'S Bylaws were amended effective March 29, 2018 along with agreement and plan of merger with The Scripps Research Institute. Form 990, Part VI, Section A, line 6 The Scripps Research Institute is the sole member of the Institute. Form 990, Part VI, Section A, line 7a The Sole Member has the power to designate all directors of the Institute. Form 990, Part VI, Section A, line 7b The Member's powers include the ability to sell, lease, exchange or dispose of all or substantially all of the property of the Institute; determinations as to substantially related to exempt purpose for licensing or other transfer of intellectual property of the Institute; fixing the compensation of the Institute's directors; and amendments to the Institute's articles and/or bylaws. Form 990, Part VI, Section B, line 11b Information used to prepare the Form 990 was compiled by CALIBR's personnel. The return was prepared with the assistance of its public accounting firm. The Form 990 was reviewed by CALIBR's Audit Committee, which has authority and oversight of CALIBR's audit and tax preparation. A complete copy of the Form 990 was provided to the full board after review by the Audit Committee and prior to filing with the IRS. Form 990, Part VI, Section B, line 12c CALIBR'S Conflict of Interest Policies and Procedures apply to members of the Board of Directors, officers, key personnel, and their family members (altogether covered individuals) to protect the interests of TSRI when it is contemplating entering into a transaction or arrangement that could: 1) Benefit the private interest of a covered individual within the meaning of Treasury Regulation Section 1.501(c)(3)-1(d)(1)(ii), 2) Result in a possible excess benefit transaction within the meaning of Section 4958(c) of the Internal Revenue Code of 1986, as amended; or 3) Be a self-dealing transaction within the meaning of Section 5233 of the California Corporations Code (the "Corporations Code"). CALIBR'S policies and procedures are intended to supplement, but not replace, any state and federal laws governing actual, potential, or apparent conflict of interest applicable to TSRI. Disclosure documents responsive to TSRI's policies are annually submitted by covered individuals, and are reviewed by TSRI administration for pertinent relationships. Any transactions or arrangements involving covered individuals that fall within the scope of the policies are then subject to review and consideration by non-conflicted Board of Director members, with conflicted members being recused from any vote to approve or disapprove. Form 990, Part VI, Section B, line 15 The compensation of the CEO and certain other key executives was reviewed and approved by the Board of Directors. This review was based, in part, on analysis performed by the Human Resources Department, and included data from outside consultants or internally-conducted research. On an ongoing basis, executives may participate in the normal annual salary increase program, which is based on a recommendation from the Human Resources Department based on market research. Any unusual or potentially non-qualified compensation would be reviewed by outside counsel for any tax compliance issues. Form 990, Part VI, Section C, line 19 Governing documents, Conflict of Interest Policy, and financial statements are available upon request. Form 990, Part XI, line 9: Transfer to The Scripps Research Institute -73,728,151. THe Scripps Research Institute 10550 North Torrey Pines Road La Jolla CA 92037 330435954 Research CA 501(c)(3) Line 4 N/A 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 The Scripps Research Institute R 73728151 FMV