2019-05-15T09:28:07-07:00 2018-12-31 134036703 SCHALL & ASHENFARB CPAS 307 5th Ave 15th Floor NEW YORK NY 100166517 990 2018-01-01 237376197 Hereditary Disease Foundation HERE 2129812121 601 West 168th Street New York NY 10032 Meghan Donaldson CEO 2019-05-15 true Michael Schall P02024184 2122682800 2018 2019-02-21 02:37:17Z Meghan Donaldson 601 West 168th Street 54 New York NY 10032 3809941 false false X hdfoundation.com X 1968 CA To fund innovative research towards curing Huntington's disease and impacting other brain disorders. 17 15 3 17 0 747377 2169236 0 432044 474934 -105152 47187 1074269 2691357 1752844 978642 0 374926 374694 68000 217779 419848 716323 2547618 2137659 -1473349 553698 11878583 10922906 1406338 844715 10472245 10078191 To fund innovative research towards curing Huntington's disease and impacting other brain disorders. false false 1670849 978642 The Hereditary Disease Foundation commemorates its 50th year by making an even greater impact toward developing novel therapeutics and cures. We have put in place strategies and new grant funding programs to maximize our effectiveness. We have been funding catalytic and paradigm-changing research since our birth - including identifying the Huntington's Disease marker in 1983 and the HD Gene in 1993, and supporting gene silencing approaches since 2002. We want to continue to make an impact by funding research that pushes the envelope.The Hereditary Disease Foundation provides funding for research that advances the discovery and development of treatments for Huntington's Disease and other brain disorders. We are passionate about funding and the Foundation intends to use the endowment funds for its scientific activities which includes providing grants to fund scientific research to further the understanding of, and to develop diagnostics and therapeutics for neurodegenerative diseases, including Huntington's Disease. The Hereditary Disease Foundation funds the most innovative, creative and paradigm-changing research possible. The data generated with HDF funding often allows researchers to get initial findings that help them apply successfully for larger, long-term funding from other funding agencies, including the National Institutes of Health. The Foundation's current focus is on:1) Modifier Studies - On DNA repair pathways, protein degradation and other modifiers of phenotype and age of onset.2) Research mechanisms of HD neurogeneration and biomarkers and therapy for HD-induced neurodegeneration.Type of funding:The Basic Research Grants Program: Supports projects contributing to identifying and understanding the fundamental defects in Huntington's Disease. Postdoctoral Fellowships: These postdoctoral fellowships are intended to cultivate interest in Huntington's Disease research by bright young scientists. Fellowships are granted to those who possess imagination, rigor, creativity and spirit to push forward toward a cure for HD and ensure that these learning can be applied to other brain diseases. 1670849 true true false false false false false false false true true false false false false true true false false true true true true true true false false true true false false false false false false false false true false false false false false false false false false false false false true 8 0 true 3 true false false false false false false true true false 0 false false false false false false false false false false false false X 17 15 true false false false false false false true true false false true true true true true false true false false CA NY X X Travis Carey 2129282121 601 West 168th Street New York NY 10033 Meghan Donaldson CEO 40.00 0.00 X X 115000 0 0 Nancy Wexler PhD President 7.00 0.00 X X 0 0 0 Alice Wexler PhD Secretary 1.00 0.00 X X 0 0 0 Bruce Donaldson Treasurer 1.00 0.00 X X 0 0 0 David Zwally Chair 1.00 0.00 X X 0 0 0 Anne Young MD PhD Vice Chair 1.00 0.00 X X 0 0 0 Berta Gehry Director 1.00 0.00 X 0 0 0 Frank Gehry Director 1.00 0.00 X 0 0 0 David Gerstenhaber Director 1.00 0.00 X 0 0 0 Kelly Posner Gerstenhaber PhD Director 1.00 0.00 X 0 0 0 Arthur Golding MD Director 1.00 0.00 X 0 0 0 David Housman PhD Director 1.00 0.00 X 0 0 0 Joan Leiman Director 1.00 0.00 X 0 0 0 Karen Newman Director 4.00 0.00 X 0 0 0 Herbert Pardes MD Director 2.00 0.00 X 0 0 0 Robi Blumenstein Director 1.00 0.00 X 0 0 0 Sandy Fox Director 1.00 0.00 X 0 0 0 Travis Carey CFO 10.00 0.00 X 26166 0 0 141166 1 false false false 0 563779 1605457 2169236 0 317442 317442 0 0 0 1213323 1055831 157492 157492 157492 62753 563779 62753 0 0 0 Other Income 47187 47187 47187 2691357 522121 636924 636924 100000 100000 241718 241718 0 141116 57500 60616 23000 0 164000 130400 4575 29025 0 39305 26471 5505 7329 30273 20388 4240 5645 0 0 0 0 68000 68000 62041 62041 155852 76094 59858 19900 0 22747 4791 17741 215 10542 7034 1783 1725 0 106867 71310 18068 17489 0 0 286372 278614 4178 3580 0 0 13996 9339 2366 2291 5419 5169 250 Printing and Publications 44531 7326 596 36609 Other 4442 2235 1359 848 Postage and Shipping 3514 705 936 1873 0 2137659 1670849 249031 217779 400213 345388 1264526 782260 272243 257108 0 0 0 0 0 19789 98022 13996 84026 9921525 9434335 0 0 0 20076 0 11878583 10922906 18749 18766 1387589 825949 1406338 844715 X 1219266 1078721 727979 474470 8525000 8525000 10472245 10078191 11878583 10922906 553698 -947752 X false true X true false X 2670705 1886920 2107686 747377 2169236 9581924 0 0 2670705 1886920 2107686 747377 2169236 9581924 2465239 7116685 305949 267915 273233 265653 317651 1430401 0 25439 25439 11037764 0.64480 0.62130 X 8401672 676151 -543488 8534335 7700419 1155712 454459 8401672 7566144 580315 446040 7700419 8250520 -225617 458759 7566144 8512186 205358 467024 8250520 0.99890 0.00110 false false false 98022 13996 84026 84026 X 1781564 -947752 100000 -847752 2629316 62041 62041 2691357 2175618 100000 100000 2075618 62041 62041 2137659 Part V, Line 4: Intended uses of the endowment fund. HDF intends to use the endowment funds for its scientific activities which includes grants to fund scientific research to further the understanding of, and to develop diagnostics and therapeutics for, neurodegenerative diseases, including Huntington's Disease. Part X : FIN48 Footnote HDF does not believe its financial statements include any material, uncertain tax positions. Tax filings for the periods ending December 31, 2015 and later are subject to examination by applicable taxing authorities. true Venezuela 0 1 Program Services Operation of a clinic 91718 Germany 0 0 Grants to recipients Scientific Research 150000 1 1 241718 241718 Germany Scientific Research 150000 Wire Trans. 1 Grant to assist in clinic operation Venezuela 1 91718 Check false false false false false false Part I, Line 2 - Grantmakers Explanation For Monitoring Use of Funds Outside US Expenses incurred outside of the United States are monitored through the submission of invoices to the central office located in New York as well as the President's consistent contact with the program director regarding program activities. X X X false Susan Quinlan Martin 350 East 55th Street New York NY 10022 Event Consultant false 626532 68000 558532 626532 68000 558532 NY CA FR events 626532 563779 62753 53960 8793 626532 563779 62753 53960 8793 62753 true Mass Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 042103594 501(c)(3) 110924 0 Massachusetts General Hosp 55 Fruit Street Boston MA 02114 042697983 501(c)(3) 75000 0 Medical College of Wisconsin 8701 W Watertown Plank Rd Wauwatosa WI 53226 390806261 501(c)(3) 75000 0 Stanford University 450 Serra Mall Stanford CA 94305 941156365 501(c)(3) 150000 0 Thomas Jefferson University 4201 Henry Avenue Philadelphia PA 19144 231352651 501(c)(3) 75000 0 Univ of California Irvine 260 Aldrich Hall Irvine CA 92697 952226406 501(c)(3) 75000 0 University of Pennsylvania 3451 Walnut Street Philadelphia PA 19104 231352685 501(c)(3) 75000 0 7 0 Scientific Research 1 100000 Grantmaker's Description of How Grants are Used HDF monitors its grants by requiring science research progress reports from grantees as a condition to further payments of any grant payable in installments, and a final report on completion of the research David Housman Board Member 107000 Research Grant Ellen Penney Daughter of Board Member 75000 Research Grant Form 990, Part VI, Line 2: Description of Business or Family Relationship of Officers, Directors, Et Nancy Wexler, President, and Alice Wexler, Secretary, are sisters and both are members of the board of directors.Meghan Donaldson, CEO, and Bruce Donaldson, Board Member, are married and are both members of the board of directors. Kelly Posner Gerstenhaber and David Gerstenhaber are married and both are members of the board of directors.Frank Gehry and Berta Gehry are married and both are members of the board of directors.Sandy Fox is the aunt of David Zwally and both are members of the board of directors. Form 990, Part VI, Line 11b: Form 990 Review Process The Foundation provides the 990 to the board of directors for approval. Form 990, Part VI, Line 12c: Explanation of Monitoring and Enforcement of Conflicts Annual conflict of interest statements are circulated to all officers, directors, and key employees at the board of directors meeting. Management maintains signed copies of these statements for all such individuals to ensure compliance with this policy. Form 990, Part VI, Line 15a: Compensation Review & Approval Process - CEO, Top Management A written employee contract is established and approved by the board or compensation committee. Form 990, Part VI, Line 19: Other Organization Documents Publicly Available The Foundation makes its financial statements and 990 available to the public on its website, www.hdfoundation.org. The Foundation makes its governing documents and conflicts of interest policy available to the public upon request.