2019-05-14T13:23:48-05:00 2018-12-31 341874260 CBIZ MHM LLC 700 WEST 47TH STREET SUITE 1100 KANSAS CITY MO 64112 990 2018-01-01 431889037 BIONEXUS KC BION 8167537700 30 W PERSHING ROAD NO 210 KANSAS CITY MO 64108 WILLIAM S BERKLEY DIRECTOR (CHAIR) 8167537700 2019-05-14 1 LISA BURKE P00220718 8169455500 12.221.96.220 2019-05-14 13:02:26 CD P DA39A3EE5E6B4B0D3255BFEF95601890AFD80709 6E6AF8105B59C12842316B28F7A612AF17130E27 2018 2019-02-21 02:37:17Z WAYNE O CARTER 30 W PERSHING ROAD NO 210 KANSAS CITY MO 64108 1806980 0 X WWW.BIONEXUSKC.ORG X 2000 MO THE PURPOSE OF THIS ORGANIZATION IS TO PROMOTE AND FOSTER DEVELOPMENT OF LIFE SCIENCES IN THE KANSAS CITY METROPOLITAN AREA AND TO PROVIDE A PLATFORM FOR DEVELOPMENT AND COOPERATION IN THE AREA OF LIFE SCIENCES IN THE KANSAS CITY METROPOLITAN AREA. 13 12 5 55 0 3680 1603349 1667012 90800 114253 9083 25151 0 106 1703232 1806522 616772 554521 0 0 697292 782856 0 0 15080 400834 532009 1714898 1869386 -11666 -62864 2003174 1940310 0 0 2003174 1940310 X THE PURPOSE OF THIS ORGANIZATION IS TO PROMOTE AND FOSTER DEVELOPMENT OF LIFE SCIENCES IN THE KANSAS CITY METROPOLITAN AREA AND TO PROVIDE A PLATFORM FOR DEVELOPMENT AND COOPERATION IN THE AREA OF LIFE SCIENCES IN THE KANSAS CITY METROPOLITAN AREA. 0 0 1531444 554521 114359 SEE SCHEDULE O 1531444 1 1 0 1 0 0 0 0 0 0 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 5 0 5 1 1 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 X 13 12 1 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 0 0 X X SHARON NEWMAN 8167537700 30 W PERSHING ROAD STE 210 KANSAS CITY MO 64108 WILLIAM S BERKLEY DIRECTOR (CHAIR) 0.50 X X 0 0 0 DONALD CRAIG BRATER DIRECTOR 0.10 X 0 0 0 WAYNE O CARTER PRESIDENT 40.00 X X 267466 0 35111 DAVID FRANTZE DIRECTOR 0.20 X 0 0 0 IRVINE O HOCKADAY JR DIRECTOR 0.30 X 0 0 0 ROBERT A KIPP DIRECTOR (VICE CHAIRMAN) 0.00 X X 0 0 0 STEPHEN REINTJES DIRECTOR (SECRETARY AND TR 0.25 X X 0 0 0 THOMAS SACK PHD DIRECTOR 0.30 X 0 0 0 ANNE D ST PETER DIRECTOR 0.30 X 0 0 0 STEVEN ST PETER MD DIRECTOR 0.30 X 0 0 0 DEBORAH WILKERSON DIRECTOR 0.30 X 0 0 0 MARIA STECKLEIN FLYNN DIRECTOR 0.20 X 0 0 0 JEFF HARGROVES DIRECTOR 0.30 X 0 0 0 KEITH A GARY VICE PRESIDENT 40.00 X 163661 0 27424 431127 0 62535 2 0 1 0 0 49623 1617389 1667012 LIFE SCIENCES DINNER 900099 51230 51230 ONE HEALTH SYMPOSIUM 900099 36393 36393 BIOINFORMATICS CONFERE 900099 26630 26630 114253 25609 25609 458 -458 -458 -458 MISCELLANEOUS REVENUE 900099 106 106 106 1806522 114359 0 25151 554521 554521 493662 347097 137316 9249 225342 134223 87206 3913 30411 17513 12898 33441 22506 10749 186 58488 33944 24544 66834 66493 341 16108 10128 4882 1098 15671 13153 2467 51 50563 27473 22680 410 30003 26046 3957 9103 8745 343 15 7716 6020 1645 51 CONSULTANTS 100535 100535 0 0 ANNUAL MTG & LIFE SCI. 92215 92215 0 0 HONORARIA 19500 19500 0 0 LIFE SCIENCES CENSUS 15000 15000 0 0 50273 36332 13834 107 1869386 1531444 322862 15080 1990906 1894536 118117 96267 12268 21850 0 23924 2003174 1940310 0 0 X 1568760 1450200 434414 490110 2003174 1940310 2003174 1940310 -62864 0 X 0 1 X 1 0 X 1532981 1897646 1724324 1603349 1667012 8425312 1532981 1897646 1724324 1603349 1667012 8425312 4379401 4045911 58 88 900 9083 27434 37563 1924 106 2030 8464905 0.47800 0.53010 X 0 1231 1231 1531444 1532675 226634 56659 0 0 231410 178496 218742 226634 855282 1282923 1707 2594 2211 1231 7743 57853 44624 54686 56659 213822 320733 47293 36939 10354 70824 59328 11496 21850 X 1806980 458 458 1806522 0 1806522 1869844 458 458 1869386 0 1869386 PART X, LINE 2: BIONEXUS KC HAS BEEN GRANTED AN EXEMPTION FROM INCOME TAXES BY THE INTERNAL REVENUE SERVICE UNDER THE PROVISIONS OF SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE. THERE WAS UNRELATED BUSINESS INCOME DURING 2018 RELATED TO PAYING FOR EMPLOYEE PARKING. THERE WAS NO UNRELATED BUSINESS INCOME DURING 2017. THE ORGANIZATION HAS EVALUATED THE STANDARDS REQUIRING DISCLOSURE OF UNCERTAIN TAX POSITIONS UNDER FASB ASC 740, INCOME TAXES, AND DETERMINED THAT THERE ARE NO MATERIAL MATTERS WHICH REQUIRE DISCLOSURE. PART XI, LINE 2D - OTHER ADJUSTMENTS: LOSS ON SALE OF FIXED ASSETS 458. PART XII, LINE 2D - OTHER ADJUSTMENTS: LOSS ON SALE OF FIXED ASSETS 458. 1 UNIVERSITY OF MISSOURI 115 BUSINESS LOOP 70W MIZZOU NH RM 501 COLUBMIA MO 65211 436003859 170(B)(1)(A)(II) 50000 BIONEXUS KC 18-10 NEXUS GRANT BRET ULERY CHILDREN'S MERCY HOSPITAL 2401 GILLHAM ROAD KANSAS CITY MO 64108 440605373 501(C)(3) 149489 BIONEXUS KC 18-04 PATTON TRUST RESEARCH GRANT: SEAN RIORDAN; BIONEXUS KC 18-06 PATTON TRUST RESEARCH GRANT VENKATESH SAMPATH; BIONEXUS KC 18-01 BLUE KC RESEARCH GRANT BRIDGETTE JONES KU MEDICAL CENTER RESEARCH INSTITUTE INC 3901 RAINBOW BLVD KANSAS CITY KS 66160 481108830 501(C)(3) 92710 BIONEXUS KC 18-05 PATTON TRUST RESEARCH GRANT: IRFAN SAADI; BIONEXUS KC 18-03 BLUE KC GRANT DAVID ROBBINS UNIVERSITY OF KANSAS CENTER FOR RESEARCH 2385 IRVING HILL ROAD LAWRENCE KS 66045 480680117 501(C)(3) 100000 EYAD AL-HIHI, MD, MBA, FACP, PCMH CCE, BIONEXUS KC 18-02; BIONEXUS KC 18-09 NEXUS GRANT LAIRD FORREST, PHD KANSAS STATE UNIVERSITY 102 ANDERSON HALL MANHATTAN KS 66506 480771751 170(B)(1)(A)(II) 100000 BIONEXUS KC 17-10 NEXUS GRANT KATHRYN REIF; BIONEXUS KC 18-08 NEXUS GRANT YAN-JANG HUANG SAINT LUKE'S HOSPITAL OF KANSAS CITY 4401 WORNALL RD KANSAS CITY MO 64111 440545297 501(C)(3) 50000 BIONEXUS KC 16-3 BLUE KC MICHAEL NASSIF SLH 4 2 PART I, LINE 2: GRANTS ARE FOR A ONE YEAR DURATION. GRANT RECIPIENTS AGREE TO PROVIDE A PROGRESS REPORT AT SIX MONTHS AND A SUMMARY TECHNICAL PROGRESS REPORT WITHIN 30 DAYS OF THE END OF THE PERFORMANCE TO INCLUDE: 1. A BRIEF SUMMARY OF TECHNICAL PROGRESS RELATIVE TO THE GOALS AND OBJECTIVES PROPOSED IN THE PROPOSAL. 2. A BRIEF STATEMENT CONCERNING THE EFFECTIVENESS AND BENEFITS REALIZED FROM THE COLLABORATIONS INVOLVED. GRANT RECIPIENTS AGREE TO PROVIDE (UPON REQUEST) A COPY OF ALL PROPOSALS SUBMITTED TO EXTERNAL FUNDING AGENCIES AS A RESULT OF THE SUPPORT PROVIDED AND SUBSEQUENTLY NOTIFY BIONEXUS KC OF ACCEPTANCE OR REJECTION THEREOF. IF THE GRANT RECIPIENT RECEIVES ALTERNATIVE FUNDS FOR SUPPORT OF THIS SPECIFIC PROJECT, BIONEXUS KC REQUESTS THAT THE RECIPIENT RETURN ANY UNEXPENDED FUNDS TO THE INSTITUTE SO THAT THEY CAN BE USED TO SUPPORT OTHER INVESTIGATORS. X X X 0 0 0 0 0 0 0 0 0 WAYNE O CARTER PRESIDENT 267466 0 0 0 0 0 27421 0 7690 0 302577 0 0 0 KEITH A GARY VICE PRESIDENT 163661 0 0 0 0 0 17228 0 10196 0 191085 0 0 0 FORM 990, PART III, LINE 4A 2018 ACCOMPLISHMENTS: 1. NAME CHANGE AND REBRANDING 2018 WAS A YEAR OF CHANGE! OUR ORGANIZATION REBRANDED TO BIONEXUS KC FROM THE KANSAS CITY AREA LIFE SCIENCES INSTITUTE. WHY BIONEXUS KC? BECAUSE WE ARE THE NEXUS OF ANIMAL AND HUMAN HEALTH AND, AS OUR TAGLINE REFLECTS, WE ARE THE "CATALYST FOR INNOVATION IN ANIMAL AND HUMAN HEALTH." 2. REGIONAL LIFE SCIENCES STRATEGIC ASSESSMENT - "PATH TO 2025" BIONEXUS KC ENGAGED DELOITTE TO EXECUTE A STRATEGIC ASSESSMENT OF THE REGIONAL LIFE SCIENCES IN 2015. THE PROCESS WAS LED BY AN EXPERIENCED STEERING COMMITTEE COMPRISED OF COMMUNITY AND BUSINESS LEADERS IN THE LIFE SCIENCES. THE COMMITTEE LOOKED AT BOTH DRIVERS OF CLUSTER ENHANCEMENT AND REGIONAL SCIENTIFIC STRENGTHS. THE REGIONAL VISION DEVELOPED THROUGH THE ASSESSMENT PROCESS STATES, "THE KANSAS CITY REGION IS A GLOBAL LEADER AT THE NEXUS OF HUMAN AND ANIMAL HEALTH BENEFITING ALL OUR CITIZENS AND THE ECONOMY." THESE NEXUS OPPORTUNITIES WILL BE DIFFERENT FOR EACH STRATEGIC AREA AND WILL LIKELY RANGE FROM USING NATURALLY OCCURRING CANCER IN DOGS FOR ACCELERATING HUMAN DISCOVERIES TO ADVANCING OUR STRENGTH IN HEALTH IT AND OUTCOMES RESEARCH. BIONEXUS KC IS THE "CATALYST FOR INNOVATION IN ANIMAL AND HUMAN HEALTH." WE LEAD PROGRAMS WHERE APPROPRIATE, WE CATALYZE RELATIONSHIPS AND OPPORTUNITIES, AND WE STIMULATE COLLABORATION AND HELP BRING EMERGING TECHNOLOGIES FROM CONCEPT TO REALITY. BIONEXUS KC IS LEADING: - COLLABORATE2CURE TO ENGAGE SCIENTISTS, CLINICIANS AND THE COMMUNITY TO COLLABORATE AND SOLVE VEXING HEALTHCARE AND SCIENTIFIC PROBLEMS - THE DEVELOPMENT OF TWO PROOF OF CONCEPT FUNDS THAT DRIVE COMMERCIALIZATION AND ECONOMIC DEVELOPMENT WHILE SUPPORTING ENTREPRENEURS - REGIONAL WORKFORCE DEVELOPMENT PROGRAMS IDENTIFYING CRITICAL SKILLS NEEDED BY INDUSTRY TO INFORM TIMELY ACADEMIC SOLUTIONS - THE REBRANDING OF BIONEXUS KC AND DEVELOPING A COHESIVE MESSAGE WITH OUR REGIONAL STAKEHOLDERS BIONEXUS KC IS CATALYZING: - THE CANCER WORKING GROUP VISION FOR A REGIONAL VETERINARY CLINICAL TRIAL FACILITY TO OPERATE AT THE NEXUS OF HUMAN AND ANIMAL CANCER AND ACCELERATE NEW THERAPEUTICS FOR PEOPLE AND PETS - PUBLIC/PRIVATE PARTNERSHIPS AND INTEGRATING OUTCOMES RESEARCH GOALS INTO NEURODEVELOPMENTAL DISORDERS (AUTISM SPECTRAL DISORDER) - PARTNERSHIPS IN HUMAN AND ANIMAL HEALTH DATA LEVERAGING OUR REGIONAL HEALTH IT EXPERTISE INTO A PLATFORM CALLED "1DATA" FOR TRANSLATIONAL RESEARCH - REGIONAL INTEREST IN VALUE-BASED HEALTHCARE LEADING A SEA CHANGE OF INNOVATION IN HUMAN HEALTH IMPROVING CLINICAL OUTCOMES AND REDUCING COSTS - A REGIONAL DEMENTIA CARE NETWORK 3. COLLABORATE2CURE BIONEXUS KC CREATED THE COLLABORATE2CURE PROGRAM WITH THE GOAL OF STIMULATING REGIONAL SCIENTIFIC COLLABORATION AND DEVELOPING INNOVATIVE WAYS TO SOLVE SCIENTIFIC CHALLENGES. BIONEXUS KC IDENTIFIES A TOPIC WITH SIGNIFICANT INTEREST TO RESEARCHERS WHICH ALIGNS WELL WITH REGIONAL EXPERTISE, AND THEN COORDINATES A SERIES OF PRESENTATIONS FROM RESEARCHERS OVER THE COURSE OF SEVERAL MONTHS. THE 2018 COLLABORATE2CURE (C2C) SERIES FOCUSED ON "VALUE-BASED HEALTHCARE AND QUALITY OUTCOMES." THIS SERIES WAS CO-CHAIRED BY DRS. STACY FARR AND CAROLE DECKER FROM THE UNIVERSITY OF MISSOURI-KANSAS CITY (UMKC) SCHOOL OF NURSING & HEALTH STUDIES AND SAINT LUKE'S MID AMERICA HEART INSTITUTE (MAHI), RESPECTIVELY. THE TWO, ALONG WITH DR. JOHN SPERTUS (UMKC, MAHI), ARE LEADING THE REGIONAL QUALITY & VALUE INNOVATION CONSORTIUM (QVIC), WHOSE VISION IS TO BRING MULTIPLE STAKEHOLDERS TOGETHER TO IMPROVE THE QUALITY AND VALUE OF HEALTHCARE. THE QVIC IS MADE POSSIBLE THROUGH THE REGIONAL, NIH-FUNDED, FRONTIERS: CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE (CTSI) ADMINISTERED BY THE UNIVERSITY OF KANSAS. MULTIPLE KEY STAKEHOLDERS GATHERED DURING THIS SERIES, INCLUDING RESEARCHERS, HEALTHCARE PROVIDERS, QUALITY IMPROVEMENT PROFESSIONALS, COMMERCIAL AND PUBLIC HEALTH INSURERS, STUDENTS, PATIENTS, ENTREPRENEURS, COMMUNITY-BASED ORGANIZATIONS, AND THE DEPARTMENT OF HEALTH. THIS C2C SERIES PROVIDED TWO DIFFERENT SESSIONS, WITH OVER 300 ATTENDEES PARTICIPATING IN 2018. THE FIRST SESSION WAS A MONTHLY GENERAL MEETING ON KEY HEALTHCARE TOPICS IDENTIFIED AS STRATEGIC PRIORITIES BY HEALTHCARE LEADERSHIP THROUGHOUT THE KC REGION. THE GENERAL SESSIONS FEATURED MULTIPLE KEY STAKEHOLDERS AS THEY PRESENTED TOPICS AND CHALLENGES FROM THEIR PERSPECTIVE (INSURER, HOSPITAL, RESEARCHER, PATIENT, AND/OR CBO), FOLLOWED BY A ROUNDTABLE DISCUSSION TO IDENTIFY OPPORTUNITIES TO COLLABORATE AND ADDRESS THESE CHALLENGES. IN ADDITION TO THE GENERAL C2C SESSIONS, A SECOND MEETING SERIES FOCUSED SPECIFICALLY ON THE RESEARCH COMMUNITY. THE C2C RESEARCHER MEETINGS WERE BI-MONTHLY, BRINGING TOGETHER OUTCOMES RESEARCHERS TO EVALUATE THE HEALTHCARE CHALLENGES DISCUSSED IN THE GENERAL C2C SESSIONS. RESEARCHERS WERE TASKED WITH DEVELOPING MEANINGFUL INTERVENTION STRATEGIES TO IMPROVE THE QUALITY AND VALUE OF HEALTHCARE FOR IMPLEMENTATION IN A MULTI-HOSPITAL NETWORK. THE C2C RESEARCHER MEETINGS ENGAGED RESEARCHERS IN INNOVATION AND BUILDING A STRONGER RESEARCH COMMUNITY ACROSS THE INTER-DISCIPLINARY FIELD OF HEALTH SERVICES RESEARCH AND HEALTHCARE QUALITY IMPROVEMENT. A SIGNIFICANT OUTCOME OF THIS YEAR'S COLLABORATE2CURE SERIES IS THAT TWO PROJECTS ARE BEING FORMULATED TO ENGAGE MULTIPLE HEALTH SYSTEMS IN A TWO-YEAR VALUE-IMPROVEMENT PROJECT, SUPPORTED BY THE RESEARCH COMMUNITY: - A PROGRAM ADDRESSING THE OPIOID EPIDEMIC - A PROGRAM ON TRANSITIONS IN CARE, FOCUSING ON HEART FAILURE, THAT WILL LEVERAGE OUR INSIGHTS INTO PATIENTS' EXPERIENCES AND ADDRESSING THE SOCIAL DETERMINANTS OF HEALTH. WHILE THE ENTIRE COUNTRY IS GRAPPLING WITH THE CHALLENGE OF IMPROVING THE QUALITY OF CARE WHILE LOWERING COSTS, KANSAS CITY CAN MODEL THE UNIQUE CULTURE AND ASSETS OF OUR REGION AS IT STRIVES TO BECOME "THE OUTCOMES CAPITOL". FORM 990, PART III, LINE 4A (CONTINUED) 4. WORKFORCE DEVELOPMENT WORKFORCE DEVELOPMENT WAS IDENTIFIED IN BIONEXUS KC'S PATH TO 2025 REPORT AS A SIGNIFICANT THREAT TO, AND CRITICAL WEAKNESS IN, THE REGIONAL LIFE SCIENCE CLUSTER. KC RISING, A CIVIC INITIATIVE UNDERWAY ACROSS THE KANSAS CITY COMMUNITY, ESTABLISHED A HUMAN CAPITAL WORK GROUP TO ADDRESS WORKFORCE DEVELOPMENT ISSUES. RECOGNIZING THE OPPORTUNITY TO LEVERAGE A PARALLEL EFFORT, BIONEXUS KC INTEGRATED ITS EFFORTS AND EXPERTISE WITH KC RISING TO DEVELOP A REGIONAL PLAN OF ACTION. 2018 ACTIVITIES IN SUPPORT OF WORKFORCE DEVELOPMENT INCLUDED THE FOLLOWING: - A KEY RECOMMENDATION FROM THE LIFE SCIENCES TALENT TO INDUSTRY EXCHANGE (TIE) PROCESS, CONDUCTED AS PART OF KC RISING, WAS TO ESTABLISH A REGIONAL ADVISORY COUNCIL (RAC). THE RAC CAN ASSESS A VARIETY OF WORKFORCE ISSUES AND IDENTIFY EDUCATION SOLUTIONS MORE RAPIDLY, EFFICIENTLY, AND MEETING INDUSTRY NEEDS. - BIOINFORMATICS WAS SELECTED AS THE FIRST FOCUS AREA FOR THE RAC, AS COMPANIES IN THIS INDUSTRY SECTOR STRUGGLE TO ACQUIRE ADEQUATELY SKILLED WORKERS. THE RAC IS CO-CHAIRED BY BARBARA BICHELMEYER (PROVOST, UMKC) AND HARLEN HAYS (MANAGER, LEAD ANALYTICS ADVISER, CERNER). THE GROUP WORKS CLOSELY WITH CERNER, NETSMART, AND IQVIA - COMPANIES EMPLOYING 80% OF THE BIOINFORMATICS WORKFORCE. - CONTRACT RESEARCH ORGANIZATIONS WILL BE THE SECOND FOCUS AREA. GIVEN THE EVER-CHANGING NATURE OF THEIR WORKFLOW, THIS INDUSTRY SECTOR IS RIPE FOR USING STACKABLE CREDENTIALS TO MEET TRAINING NEEDS. THESE SHORT-TERM CREDENTIALS CAN BE "STACKED," LEADING TO TWO AND FOUR-YEAR DEGREES. - THE EMERGING ENTREPRENEUR PROOF OF CONCEPT FUND (E2POC). THE GOAL OF THE EMERGING ENTREPRENEUR PROOF OF CONCEPT FUND (E2POC) IS TO SUPPORT OUR REGION'S YOUNG EMERGING ENTREPRENEURS AND SECURE EVOLVING TECHNOLOGIES FOR REGIONAL ECONOMIC DEVELOPMENT. THE E2POC PROGRAM INVESTS IN EARLY-STAGE, HIGH POTENTIAL TECHNOLOGIES DEVELOPED BY STUDENTS PARTICIPATING IN REGIONAL STEM COMPETITIONS. TO INCREASE ENTREPRENEURS IN THE REGION, THE E2POC PROGRAM STRENGTHENS STUDENT INVENTORS THROUGH ONLINE RESOURCES, BUSINESS PLAN DEVELOPMENT ASSISTANCE, MARKET ASSESSMENTS, INTELLECTUAL PROPERTY PROTECTION, AND ACCESS TO CAPITAL. IN THE PROGRAM, STUDENTS WILL RECEIVE $5,000 PER YEAR IN SCHOLARSHIP MONEY (UP TO $20,000 TOTAL). THE E2POC WILL FUND THE WORK AND PATENT FEES. THE ENTREPRENEUR IS PAIRED WITH BUSINESS MENTORS TO AUGMENT THEIR ENTREPRENEURIAL EDUCATION. LOCAL UNIVERSITIES AND COLLEGES HAVE COMMITTED TO MATCHING THE E2POC SCHOLARSHIP FUNDS, PROVIDING A STRONG INCENTIVE FOR THESE STUDENTS TO STAY IN THE REGION. 5. BIONEXUS KC'S RESEARCH DEVELOPMENT GRANT PROGRAMS BIONEXUS KC'S RESEARCH DEVELOPMENT GRANTS PROGRAM IS OUR OLDEST AND MOST POPULAR PROGRAM. GRANTS ARE AWARDED TO GENERATE PRELIMINARY DATA THAT SUPPORT SUBMISSION OF MAJOR MULTIDISCIPLINARY RESEARCH PROPOSALS TO GOVERNMENT OR PRIVATE FUNDING AGENCIES. APPLICANTS RECEIVE WRITTEN PEER REVIEWS, REGARDLESS OF WHETHER THEIR PROJECT RECEIVED FUNDING, TO HELP THEM IMPROVE FUTURE GRANT APPLICATIONS. THIS IS A VALUED SERVICE APPRECIATED BY ALL TEN STAKEHOLDERS. FROM 2007 TO 2018, BIONEXUS KC MANAGED 108 GRANTS TOTALING $5 MILLION. ON AVERAGE, FOR EVERY $1 INVESTED IN GRANTS, $11.70 HAS BEEN RETURNED TO THE REGION FROM FOLLOW-ON FEDERAL SOURCES. IMPORTANTLY, THIS NUMBER SHOULD BE VIEWED CONSERVATIVELY AS NO INFORMATION IS READILY AVAILABLE REGARDING GRANTS MADE TO REGIONAL SCIENTISTS BY PRIVATE FOUNDATIONS AND PATIENT ADVOCACY ORGANIZATIONS. THE 2018 BIONEXUS KC RESEARCH DEVELOPMENT GRANT PORTFOLIO INCLUDES: BLUE KC OUTCOMES RESEARCH GRANTS BCBS ANNOUNCED IN 2018 THAT THEY WOULD BE CHANGING THEIR APPROACH IN FUTURE GRANTS. IN 2019, BIONEXUS KC WILL WORK WITH BCBS IN SEEKING HIGHER COMMUNITY IMPACT FOR THEIR GRANT PROGRAM BY OFFERING ONE $400,000 GRANT OVER TWO YEARS FOR PROJECTS ASSESSING THE IMPACT OF ACCESS TO HEALTHFUL FOODS ON FOOD INSECURE POPULATIONS. PAUL PATTON CHARITABLE TRUST GRANTS FOCUS ON GENETIC DISEASES MAINLY AFFECTING CHILDREN. THE FUNDS FOR THIS PROGRAM ARE PROVIDED BY THE PAUL PATTON TRUST, TED C. MCCARTER, WILLIAM EVANS JR. AND BANK OF AMERICA, N.A., TRUSTEE. BIONEXUS KC AWARDED GRANTS OF UP TO $50,000 TO THREE RESEARCHERS, TWO AT CHILDREN'S MERCY, AND ONE AT THE UNIVERSITY OF KANSAS MEDICAL CENTER. NEXUS OF HUMAN AND ANIMAL HEALTH GRANTS FOCUS ON BIOMEDICAL RESEARCH PROJECTS, RANGING FROM USING NATURALLY OCCURRING DISEASES IN ANIMALS AS A MODEL FOR ASSESSING HUMAN DRUG EFFICACY TO REPURPOSING HUMAN DRUGS FOR USE IN ANIMAL DISEASES. FUNDED BY THE HALL FAMILY FOUNDATION, BIONEXUS KC AWARDED $50,000 GRANTS EACH TO THREE RESEARCHERS, ONE EACH TO KANSAS STATE UNIVERSITY, THE UNIVERSITY OF MISSOURI, AND UNIVERSITY OF KANSAS. 6. 2018 ANNUAL DINNER AND "SCIENCE TO ART" AUCTION CLOSE TO 500 COMMUNITY LEADERS, SCIENTIFIC LEADERS, AND COLLEGE AND HIGH SCHOOL STUDENTS ATTENDED THE SEPTEMBER 20, 2018 ANNUAL DINNER. DR. DAVID NASH, DEAN OF THE JEFFERSON COLLEGE OF POPULATION HEALTH AT THOMAS JEFFERSON UNIVERSITY. HIS PRESENTATION, 'LEADERSHIP FOR IMPROVING HEALTH,' EXPLAINED ALARMING TRENDS IN POPULATION HEALTH. "FOR THE FIRST TIME SINCE THE END OF WWII, THE NEXT GENERATION ARE AT RISK OF HAVING A SHORTER LIFESPAN THAN FOLKS BORN AROUND 1950," DR. NASH SAID. SPECIFICALLY, IN KANSAS CITY, THERE IS A 14-YEAR DISPARITY IN LIFE EXPECTANCY BETWEEN THE POOREST AND WEALTHIEST ZIP CODES. SOCIAL DETERMINANTS OF HEALTH, SUCH AS POVERTY AND EDUCATION, ARE A VERY IMPORTANT PART OF DRIVING THE LEVEL OF WELLNESS IN A SOCIETY. DR. WAYNE CARTER, PRESIDENT AND CEO FOR THE PAST SIX YEARS WAS HONORED FOR HIS CONTRIBUTION TO THE LIFE SCIENCES REGION. THE FIFTH SCIENCE TO ART SILENT AUCTION RAISED OVER $5,000 WHICH WAS MATCHED BY BIONEXUS KC TO SUPPORT STEAM EDUCATION, SPECIFICALLY BIOGENEIUS, PREP-KC, SCIENCE CITY AND THE GREATER KANSAS CITY SCIENCE & ENGINEERING FAIR, AND FREE EDUCATIONAL PROGRAMS AT THE KEMPER MUSEUM. 7. ONE HEALTH - NEXUS PROOF OF CONCEPT FUND: THE NEXUS OF ANIMAL AND HUMAN HEALTH PROOF OF CONCEPT FUND IDENTIFIES AND DEVELOPS TECHNOLOGIES AT THE NEXUS OF ANIMAL AND HUMAN HEALTH. BASED ON THE SUCCESSFUL MODEL OF THE CENTER FOR ANIMAL HEALTH AND INNOVATION, INVESTMENTS UP TO $250,000 WILL BE INVESTED TO DE-RISK PROMISING TECHNOLOGY TO STIMULATE ADDITIONAL INVESTMENT. - ONE HEALTH RESEARCH SYMPOSIUM: THE 2018 ONE HEALTH RESEARCH SYMPOSIUM FOCUSED ON ONE HEALTH APPLICATIONS OF CRISPR/CAS9, A GENE EDITING TECHNOLOGY WITH THE POTENTIAL OF TRANSFORMING GLOBAL HEALTH. ITS MANY APPLICATIONS INCLUDE CORRECTING GENETIC DEFECTS, TREATING AND PREVENTING THE SPREAD OF DISEASES AND IMPROVING CROPS. - BIONEXUS KC COORDINATED THIS TWO-DAY EVENT ALONG WITH THE UNIVERSITY OF MISSOURI, KANSAS STATE UNIVERSITY AND INDUSTRY PARTNERS. THE SYMPOSIUM FEATURED OVER 20 NATIONAL AND REGIONAL EXPERTS ADDRESSING THIS TOPIC. CRISPR STANDS FOR CLUSTERS OF REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS AND IS AN IMMUNE FUNCTION THAT BACTERIA USE TO FIGHT VIRUSES. THERE WERE SEVERAL APPLICATIONS PRESENTED INCLUDING: - USING CRISPR FOR DUCHENNE MUSCULAR DYSTROPHY AND IN PRECISION CANCER MEDICINE. - CRISPR APPROACH TO IMPROVE ANIMAL WELFARE, SUSTAINABILITY AND FOOD SECURITY. - INTELLECTUAL PROPERTY AND ETHICAL IMPLICATIONS OF GENE EDITING. - ONE HEALTH DAY: BIONEXUS KC PARTNERED WITH KANSAS STATE UNIVERSITY AND BIOKANSAS TO HOST "KANSAS CITY ONE HEALTH DAY." A KEYNOTE PRESENTATION WAS GIVEN BY DR. MIKE APLEY FROM KANSAS STATE UNIVERSITY ENTITLED 'ANTIBIOTIC RESISTANCE - A ONE HEALTH PERSPECTIVE.' THE EVENT INCLUDED A STUDENT POSTER COMPETITION AND AN EXPERT PANEL THAT EXPLORED ANTIMICROBIAL RESISTANCE THROUGH A ONE HEALTH LENS AND ANSWERED QUESTIONS FROM THE AUDIENCE. THE PANELISTS WERE MIKE APLEY, PHD, DVM, DACVCP, KANSAS STATE UNIVERSITY, MICHAEL MEYER, PHD, U.S. GEOLOGICAL SURVEY, NADYNE HAGMEIER, RN, KANSAS FOUNDATION FOR MEDICAL CARE INC. AND MASAKO MIZUSAWA, MD, PHD, MS, UNIVERSITY OF MISSOURI-KANSAS CITY. DR. KEITH GARY, VICE PRESIDENT OF BIONEXUS KC, CONCLUDED THE EVENT BY AWARDING FIVE STUDENTS SCHOLARSHIPS IN RECOGNITION OF THEIR ONE HEALTH-FOCUSED RESEARCH POSTERS. THESE AWARDS WERE FUNDED BY BIOKANSAS. FORM 990, PART III, LINE 4A (CONTINUED) 8. BIOINFORMATICS IN PARTNERSHIP WITH CHILDREN'S MERCY AND THE UNIVERSITY OF MISSOURI, BIONEXUS KC PRESENTED THE THIRD ANNUAL MIDWEST BIOINFORMATICS CONFERENCE ON APRIL 11-12, 2018. FEATURING 31 SPEAKERS, THIS EVENT BROUGHT TOGETHER NEARLY 200 BIOINFORMATICS-MINDED RESEARCHERS FROM ACADEMIA AND INDUSTRY TO DISCOVER CAPABILITIES, SHARE TACTICAL APPROACHES TO PROBLEM-SOLVING, AND EXPLORE SYNERGIES AND POTENTIAL COLLABORATIONS. THE CONFERENCE WAS HOSTED ON THE UNIVERSITY OF MISSOURI CAMPUS. ADDITIONALLY, BIOINFORMATICS STUDENTS LEARNED ABOUT EMPLOYMENT OPPORTUNITIES WITHIN THE REGION AND PARTICIPATED IN MOCK INTERVIEWS. INTRODUCED THIS YEAR, A SUBSET OF 33 STUDENT POSTERS WAS CONSIDERED FOR PODIUM PRESENTATIONS, WITH FOUR STUDENTS SELECTED FOR THIS HONOR. KEYNOTE SPEAKERS WERE JOHNNY PARK, PHD, FOUNDER AND CEO OF SPENCA TECHNOLOGIES, "PRECISION AG - THE NEXT REVOLUTION IN AGRICULTURE TO FEED 10 BILLION PEOPLE IN 2050 AND MARYLYN DR. RITCHIE, PHD, PRINCIPAL INVESTIGATOR, DIRECTOR, CENTER FOR TRANSLATIONAL BIOINFORMATICS, INSTITUTE FOR BIOMEDICAL INFORMATICS, ASSOCIATE DIRECTOR FOR BIOINFORMATICS, INSTITUTE FOR BIOMEDICAL INFORMATICS, ASSOCIATE DIRECTOR, CENTER FOR PRECISION MEDICINE AT THE UNIVERSITY OF PENNSYLVANIA, "MACHINE LEARNING STRATEGIES IN THE GENOME AND THE PHENOME - TOWARD A BETTER UNDERSTANDING OF COMPLEX TRAITS". FORM 990, PART VI, SECTION A, LINE 2 ANNE D. ST. PETER AND STEVEN ST. PETER,MD HAVE A FAMILY RELATIONSHIP. FORM 990, PART VI, SECTION B, LINE 11B THE ORGANIZATION HAS A POLICY FOR THE ORGANIZATION'S AUDIT COMMITTEE TO REVIEW THE 990 BEFORE IT IS FILED. FORM 990, PART VI, SECTION B, LINE 12C ALL STAFF AND DIRECTORS MUST SUBMIT ANY CONFLICTS OF INTEREST ON AN ANNUAL BASIS. IF A CONFLICT ARISES WITHIN THE BOARD, THE DISCLOSING INDIVIDUAL SHALL NEITHER VOTE NOR ENDEAVOR TO INFLUENCE THE DECISION. FORM 990, PART VI, SECTION B, LINE 15A COMPENSATION OF THE ORGANIZATION'S PRESIDENT IS AGREED UPON BY THE BOARD OF DIRECTORS AND FINALIZED VIA A WRITTEN EMPLOYMENT CONTRACT. THIS APPROVAL IS DOCUMENTED IN THE MINUTES OF THE BOARD. IN 2013 THE ORGANIZATION CREATED A COMPENSATION COMMITTEE AND CONDUCTED A COMPENSATION STUDY TO FURTHER REFINE THE COMPENSATION PROCESS. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY, AND FINANCIAL STATEMENTS ARE ONLY AVAILABLE UPON REQUEST.