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        <FormAndLineReferenceDesc>PART IV, LINE 9B</FormAndLineReferenceDesc>
        <ExplanationTxt>THE SUPPORTING ORGANIZATION HOLDS LESS THAN 1% OF THE STOCK OF MBI, INC., A BUSINESS CORPORATION OF WHICH THE SETTLOR, THEODORE R. STANLEY ("TRS"), (DECEASED 2016), WAS ALSO A SHAREHOLDER. TRS WAS NOT A TRUSTEE OF THE SUPPORTING ORGANIZATION BUT WAS A SUBSTANTIAL CONTRIBUTOR TO IT UNDER THE DEFINITION OF IRC SECTION 4946 AND THEREFORE A DISQUALIFIED PERSON. THE STANLEY FAMILY FOUNDATION ("THE FOUNDATION") IS ALSO A SUBSTANTIAL CONTRIBUTOR TO THE SUPPORTING ORGANIZATION AND THEREFORE IS CONSIDERED A DISQUALIFIED PERSON UNDER IRC SECTION 4946. MBI, INC. IS DEEMED TO BE A CONTROLLED ENTITY OF THE STANLEY FAMILY FOUNDATION BECAUSE THE FOUNDATION OWNS MORE THAN 50% OF THE VALUE OF THE MBI, INC. STOCK. AT THE END OF TAX YEAR 2018, MBI, INC. SHARES CONSTITUTED APPROXIMATELY 5.7% OF THE TOTAL ASSETS OF THE SUPPORTING ORGANIZATION.</ExplanationTxt>
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        <FormAndLineReferenceDesc>PART IV, LINE 9C</FormAndLineReferenceDesc>
        <ExplanationTxt>TRUSTEE JONATHAN STANLEY, SON OF THE SUPPORTING ORGANIZATION'S SETTLOR, THEODORE R. STANLEY, HAS A BENEFICIAL INTEREST IN SHARES OF MBI, INC. AND IS A DISQUALIFIED PERSON BY REASON OF HIS RELATIONSHIP TO THE SETTLOR AND HIS POSITION AS A TRUSTEE OF THE SUPPORTING ORGANIZATION. JULIUS FRIESE, A TRUSTEE OF THE SUPPORTING ORGANIZATION, IS AN EMPLOYEE OF MBI. THE STANLEY FAMILY FOUNDATION, OF WHICH JONATHAN STANLEY AND JULIUS FRIESE ARE TRUSTEES, IS A SUBSTANTIAL CONTRIBUTOR TO THE SUPPORTING ORGANIZATION AND HAS AN OWNERSHIP INTEREST IN MBI, INC. THE FUNDING OF THE SUPPORTING ORGANIZATION WITH STOCK OF MBI, INC. AND THE RELATIONSHIPS TO MBI OF TRS, JONATHAN STANLEY, AND JULIUS FRIESE WERE ALL DISCLOSED ON THE FORM 1023 FILED FOR THE SUPPORTING ORGANIZATION AND APPROVED BY THE INTERNAL REVENUE SERVICE.</ExplanationTxt>
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          <AddressLine2>RESTRICTED</AddressLine2>
          <City>RESTRICTED</City>
          <State>RESTRICTED</State>
          <ZIPCode>RESTRICTED</ZIPCode>
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        <Desc>INVESTMENTS HELD BY THE BROAD INSTITUTE, INC.</Desc>
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      <TotalLiabilityAmt>20000000</TotalLiabilityAmt>
      <TotalRevEtcAuditedFinclStmtAmt>51715645</TotalRevEtcAuditedFinclStmtAmt>
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      <RevenueNotReportedAmt>-1856743</RevenueNotReportedAmt>
      <RevenueSubtotalAmt>53572388</RevenueSubtotalAmt>
      <RevenueNotReportedFinclStmtAmt>0</RevenueNotReportedFinclStmtAmt>
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      <ExpensesNotReportedAmt>0</ExpensesNotReportedAmt>
      <ExpensesSubtotalAmt>44040067</ExpensesSubtotalAmt>
      <ExpensesNotRptFinclStmtAmt>0</ExpensesNotRptFinclStmtAmt>
      <TotalExpensesPerForm990Amt>44040067</TotalExpensesPerForm990Amt>
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          <BusinessNameLine1Txt>THE BROAD INSTITUTE INC</BusinessNameLine1Txt>
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          <AddressLine1Txt>415 MAIN STREET</AddressLine1Txt>
          <CityNm>CAMBRIDGE</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02142</ZIPCd>
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        <RecipientEIN>263428781</RecipientEIN>
        <IRCSectionDesc>501(C)(3)</IRCSectionDesc>
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        <ExplanationTxt>PLEDGES AND DISTRIBUTIONS ARE APPROVED BY THE TRUSTEES AND DOCUMENTED IN THE TRUSTEE MEETING MINUTES. PLEDGES AND DISTRIBUTIONS WERE PROVIDED TO THE BROAD INSTITUTE, INC., WHICH IS THE STANLEY FUND FOR THE BROAD INSTITUTE'S SUPPORTED ORGANIZATION.</ExplanationTxt>
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        <ExplanationTxt>AS AN ELEMENT OF HIS AMENDED AND RESTATED EMPLOYMENT CONTRACT EFFECTIVE JULY 1, 2014, THE PRESIDENT/CEO RECEIVED A LUMP SUM PAYMENT OF $536,377 ON JUNE 30, 2018 AND 2019, RESPECTIVELY, WHICH HE WAS ENTITLED TO RECEIVE UPON REMAINING IN THE POSITION OF CORE FACULTY MEMBER OF THE BROAD INSTITUTE.</ExplanationTxt>
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        <ContributionCnt>2</ContributionCnt>
        <NoncashContributionsRptF990Amt>25266237</NoncashContributionsRptF990Amt>
        <MethodOfDeterminingRevenuesTxt>FMV</MethodOfDeterminingRevenuesTxt>
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        <NonCashCheckboxInd>X</NonCashCheckboxInd>
        <ContributionCnt>1</ContributionCnt>
        <NoncashContributionsRptF990Amt>1937672</NoncashContributionsRptF990Amt>
        <MethodOfDeterminingRevenuesTxt>FMV</MethodOfDeterminingRevenuesTxt>
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        <FormAndLineReferenceDesc>PART I, COLUMN (B):</FormAndLineReferenceDesc>
        <ExplanationTxt>THE NUMBER OF CONTRIBUTIONS ARE USED FOR REPORTING THE LIST OF NONCASH CONTRIBUTIONS.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART III, LINE 4A:</FormAndLineReferenceDesc>
        <ExplanationTxt>THE STANLEY FUND FOR THE BROAD INSTITUTE (THE "FUND") WAS ESTABLISHED UNDER A TRUST AGREEMENT BY THE SETTLOR AND TRUSTEES ON APRIL 22, 2014. THE FUND WAS ESTABLISHED AS A TYPE I SUPPORTING ORGANIZATION OF THE BROAD INSTITUTE, INC., A BIOMEDICAL RESEARCH INSTITUTE CREATED THROUGH COLLABORATIVE EFFORTS OF THE MASSACHUSETTS INSTITUTE OF TECHNOLOGY AND HARVARD UNIVERSITY ("THE BROAD"). THE BROAD'S OVERALL MISSION IS TO PROPEL PROGRESS IN BIOMEDICINE THROUGH RESEARCH AIMED AT THE UNDERSTANDING AND TREATMENT OF DISEASE, AND THE DISSEMINATION OF SCIENTIFIC KNOWLEDGE TO THE SCIENTIFIC COMMUNITY TO BENEFIT THE PUBLIC. ONE OF THE BROAD'S RESEARCH AREAS IS PSYCHIATRIC DISEASES. IN THAT AREA, THE BROAD OPERATES THE STANLEY CENTER FOR PSYCHIATRIC RESEARCH ("THE STANLEY CENTER"), WHICH HAS THE SPECIFIC MISSION "TO REDUCE THE BURDEN OF SERIOUS MENTAL ILLNESS THROUGH RESEARCH." THE STANLEY CENTER CARRIES ON WORK IN COLLABORATION WITH INVESTIGATORS THROUGHOUT THE WORLD. THE FUND PROVIDES FINANCIAL SUPPORT FOR THE ACTIVITIES OF THE STANLEY CENTER AT THE BROAD. IT IS MANAGED BY A BOARD OF TRUSTEES. THE FUND'S ACTIVITIES ARE THE INVESTMENT OF ASSETS AND THE PAYMENT OF FUNDS TO THE BROAD IN SUPPORT OF ITS CHARITABLE AND SCIENTIFIC PURPOSES UNDER THE DIRECTION OF THE TRUSTEES SELECTED BY THE BROAD.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION A, LINE 2</FormAndLineReferenceDesc>
        <ExplanationTxt>TRUSTEES JULIUS FRIESE AND JONATHAN STANLEY HAVE A BUSINESS RELATIONSHIP. TRUSTEES ERIC LANDER, STEVEN E. HYMAN, AND EDWARD SCOLNICK HAVE A BUSINESS RELATIONSHIP.</ExplanationTxt>
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      <SupplementalInformationDetail>
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        <ExplanationTxt>THERE ARE NO COMMITTEES WITH AUTHORITY TO ACT ON BEHALF OF THE GOVERNING BODY.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 11B</FormAndLineReferenceDesc>
        <ExplanationTxt>THE STANLEY FUND FOR THE BROAD INSTITUTE'S FORM 990 WAS PREPARED WITH THE ASSISTANCE OF THE FUND'S TAX PREPARER, BLUM, SHAPIRO AND COMPANY, P.C. THE DRAFT FORM 990 WAS PROVIDED TO ALL TRUSTEES FOR REVIEW AND COMMENT PRIOR TO THE FORM BEING FILED WITH THE IRS.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 12C</FormAndLineReferenceDesc>
        <ExplanationTxt>EACH TRUSTEE IS REQUIRED TO ANNUALLY ACKNOWLEDGE HIS/HER FAMILIARITY WITH THE CONFLICT OF INTEREST POLICY AND DISCLOSE IN WRITING ANY EXISTING FINANCIAL OR OTHER MATERIAL INTERESTS SUBJECT TO THIS POLICY BY COMPLETING A CONFLICT OF INTEREST DISCLOSURE STATEMENT. THE CONFLICT OF INTEREST DISCLOSURE STATEMENTS ARE REVIEWED ANNUALLY BY THE TRUSTEES. DISCUSSION AND ACTIONS TAKEN, IF NEEDED, RELATED TO THE CONFLICT OF INTEREST DISCLOSURE ARE HELD AT TRUSTEE MEETINGS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 15</FormAndLineReferenceDesc>
        <ExplanationTxt>NO COMPENSATION IS PAID BY THE STANLEY FUND FOR THE BROAD INSTITUTE.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION C, LINE 18</FormAndLineReferenceDesc>
        <ExplanationTxt>THE FORM 990 IS MADE AVAILABLE UPON REQUEST AND ON GUIDESTAR.ORG. THE FORM 1023 IS MADE AVAILABLE UPON REQUEST.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION C, LINE 19</FormAndLineReferenceDesc>
        <ExplanationTxt>THE ORGANIZATION'S GOVERNING DOCUMENTS, CONFLICT OF INTEREST POLICY AND FINANCIAL STATEMENTS ARE AVAILABLE TO THE PUBLIC UPON REQUEST.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VII:</FormAndLineReferenceDesc>
        <ExplanationTxt>TRUSTEES STEVEN E. HYMAN AND EDWARD SCOLNICK ARE CORE MEMBERS OF THE BROAD INSTITUTE WHO RECEIVE NO COMPENSATION FROM THE STANLEY FUND FOR THE BROAD INSTITUTE OR RELATED ORGANIZATIONS.</ExplanationTxt>
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