2021-12-23T07:42:59-08:00 2020-12-31 134036703 SCHALL & ASHENFARB CPAS 307 5th Ave 15th Floor NEW YORK NY 10016 990 2020-01-01 237376197 Hereditary Disease Foundation HERE 2129812121 601 West 168th Street 54 New York NY 10032 Meghan Donaldson CEO 2021-12-23 true Meghan Donaldson 999009999 Michael Schall P02024184 2122682800 2 AAL1 IAL1 FAL1 2020 2022-09-23 18:48:47Z Meghan Donaldson 601 West 168th Street 54 New York NY 10032 6567299 false X hdfoundation.com X 1968 CA To fund innovative research towards curing Huntington's disease and impacting other brain disorders. 16 15 3 1 0 1650090 3654196 0 330387 387663 47508 17960 2027985 4059819 1467686 1782780 0 367598 364606 72000 68000 186206 394547 304275 2301831 2519661 -273846 1540158 12457716 15507063 1141006 1781608 11316710 13725455 To fund innovative research towards curing Huntington's disease and impacting other brain disorders. false false 2146127 1782780 The Hereditary Disease Foundation commemorates its 52nd year by making an even greater impact toward developing novel therapeutics and cures. We have put in place strategies and new grant funding programs to maximize our effectiveness. We have been funding catalytic and paradigm-changing research since our birth - including identifying the Huntington's Disease marker in 1983 and the HD Gene in 1993, and supporting gene silencing approaches since 2002. We want to continue to make an impact by funding research that pushes the envelope.The Hereditary Disease Foundation provides funding for research that advances the discovery and development of treatments for Huntington's Disease and other brain disorders. We are passionate about funding and the Foundation intends to use the endowment funds for its scientific activities which includes providing grants to fund scientific research to further the understanding of, and to develop diagnostics and therapeutics for neurodegenerative diseases, including Huntington's Disease. The Hereditary Disease Foundation funds the most innovative, creative and paradigm-changing research possible. The data generated with HDF funding often allows researchers to get initial findings that help them apply successfully for larger, long-term funding from other funding agencies, including the National Institutes of Health. The Foundation's current focus is on:1) Modifier Studies - On DNA repair pathways, protein degradation and other modifiers of phenotype and age of onset.2) Research mechanisms of HD neurogeneration and biomarkers and therapy for HD-induced neurodegeneration.Type of funding:The Basic Research Grants Program: Supports projects contributing to identifying and understanding the fundamental defects in Huntington's Disease. Postdoctoral Fellowships: These postdoctoral fellowships are intended to cultivate interest in Huntington's Disease research by bright young scientists. Fellowships are granted to those who possess imagination, rigor, creativity and spirit to push forward toward a cure for HD and ensure that these learning can be applied to other brain diseases. 2146127 true true false false false false false false false true true false false false false true true false false false true true false true true false false true true false false false false false true false false false false false false false false false false false false true 7 0 true 3 true false false false false false false false 0 false false false false false false false X 16 15 true false false false false false false true true false false true true true true true false true false false CA NY X X Travis Carey 2129282121 601 West 168th Street New York NY 10033 Meghan Donaldson CEO 30.00 0.00 X X 110000 0 0 Travis Carey CFO 3.00 0.00 X 15030 0 0 Nancy Wexler PhD President 7.00 0.00 X X 0 0 0 Alice Wexler PhD Secretary 1.00 0.00 X X 0 0 0 Bruce Donaldson Treasurer 1.00 0.00 X X 0 0 0 David Zwally Chair 1.00 0.00 X X 0 0 0 Anne Young MD PhD Vice Chair 1.00 0.00 X X 0 0 0 Berta Gehry Director 1.00 0.00 X 0 0 0 Frank Gehry Director 1.00 0.00 X 0 0 0 David Gerstenhaber thru 920 Director 1.00 0.00 X 0 0 0 Kelly Posner Gerstenhaber PhD Director 1.00 0.00 X 0 0 0 Barry Evenchick Director 1.00 0.00 X 0 0 0 David Housman PhD Director 1.00 0.00 X 0 0 0 Joan Leiman Director 1.00 0.00 X 0 0 0 Karen Newman Director 6.00 0.00 X 0 0 0 Herbert Pardes MD Director 2.00 0.00 X 0 0 0 Robi Blumenstein Director 1.00 0.00 X 0 0 0 Sandy Fox Director 1.00 0.00 X 0 0 0 125030 1 false false false 0 82760 3571436 3654196 0 262035 262035 0 0 0 2633108 2507480 125628 125628 125628 82760 0 0 0 Other Income 17960 17960 17960 4059819 405623 1263008 1263008 100000 100000 419772 419772 0 125030 55000 48030 22000 0 172000 137600 3775 30625 0 46030 29573 9904 6553 21546 15940 2074 3532 0 0 0 0 68000 68000 67303 67303 100735 45435 28000 27300 0 8754 8754 17368 12850 1672 2846 0 53700 37122 6134 10444 0 0 8646 8167 354 125 0 0 19605 14504 1887 3214 7170 5304 691 1175 Postage and Shipping 18162 155 8465 9542 Other 2832 1697 285 850 0 2519661 2146127 187328 186206 258816 272171 891676 2379491 24309 416443 0 0 0 0 0 20343 9868 98022 53205 64422 44817 11198150 12384273 0 0 0 0 12457716 15507063 17500 13170 1123506 1768438 1141006 1781608 X 1513539 3139960 9803171 10585495 11316710 13725455 12457716 15507063 1540158 868587 X false true X true false X 2107686 747377 2169236 1650090 1877390 8551779 0 0 2107686 747377 2169236 1650090 1877390 8551779 2882230 5669549 273233 265653 317651 295551 262035 1414123 0 25439 47508 17960 90907 10056809 0.56380 0.64920 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 9703171 1026040 485159 10244052 8534335 1595553 426717 9703171 8401672 676151 -543488 8534335 7700419 1155712 454459 8401672 7566144 580315 446040 7700419 1.00000 false false false 98022 53205 44817 44817 X 4961103 868587 100000 968587 3992516 67303 67303 4059819 2552358 100000 100000 2452358 67303 67303 2519661 Part V, Line 4: Intended uses of the endowment fund. HDF intends to use the endowment funds for its scientific activities which includes grants to fund scientific research to further the understanding of, and to develop diagnostics and therapeutics for, neurodegenerative diseases, including Huntington's Disease. Part X : FIN48 Footnote HDF does not believe its financial statements include any material, uncertain tax positions. Tax filings for the periods ending December 31, 2017 and later are subject to examination by applicable taxing authorities. true Canada 0 0 Grants to recipients Scientific Research 202652 Spain 0 0 Grants to recipients Scientific Research 75000 United Kingdom 0 0 Grants to recipients Scientific Research 67120 Sweden 0 0 Grants to recipients Scientific Research 75000 419772 419772 Canada Scientific Research 127652 Wire Trans. Canada Scientific Research 75000 Wire Trans. Spain Scientific Research 75000 Wire Trans. Sweden Scientific Research 75000 Wire Trans. United Kindom Scientific Research 67120 Wire Trans. 5 false false false false false false Part I, Line 2 - Grantmakers Explanation For Monitoring Use of Funds Outside US HDF monitors its grants by requiring science research progress reports from grantees as a condition to further payments of any grant payable in installments, and a final report on completion of the research X X X true Susan Quinlan Martin 350 East 55th Street New York NY 10022 Event Consultant false 82760 68000 14760 82760 68000 14760 NY CA FR events 82760 82760 82760 82760 true California Institute of Tech 1200 E California Blvd Pasadena CA 91125 951643307 75000 0 Columbia University Med Ctr 1790 Broadway New York NY 10019 135598093 75000 0 Ludwig Inst for Cancer Resea 666 3rd Ave New York NY 10017 237121131 129056 0 Mass Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 042103594 75000 0 Massachusetts General Hosp 55 Fruit Street Boston MA 02114 042697983 126536 0 New York Genome Center Inc 101 6th Ave New York NY 10013 800631734 75000 0 The Trustees Of Columbia Uni 535 W 116th St New York NY 10027 135598093 150000 0 Univ of California Irvine 260 Aldrich Hall Irvine CA 92697 952226406 75000 0 University Mass Medical Sch 281 Lincoln St Worcester MA 01605 043167352 120380 0 University of Califonria 1111 Franklin St12th floor Oakland CA 94607 943067788 75000 0 University of Rochester 500 Joseph C Wilson Blvd Rochester NY 14627 160743209 75000 0 UT Southwestern MedicalCenter 5323 Harry Hines Blvd Dallas TX 75390 756002868 137036 0 Whitehead Institute 455 Main St Cambridge MA 02142 061043412 75000 0 13 0 Scientific Research - Gehry Prize 1 100000 Grantmaker's Description of How Grants are Used HDF monitors its grants by requiring science research progress reports from grantees as a condition to further payments of any grant payable in installments, and a final report on completion of the research David Housman Board Member 75000 Research Grant Form 990, Part VI, Line 2: Description of Business or Family Relationship of Officers, Directors, Et Nancy Wexler, President, and Alice Wexler, Secretary, are sisters and both are members of the board of directors.Meghan Donaldson, CEO, and Bruce Donaldson, Board Member, are married and are both members of the board of directors. Kelly Posner Gerstenhaber and David Gerstenhaber are married and both are members of the board of directors.Frank Gehry and Berta Gehry are married and both are members of the board of directors.Sandy Fox is the aunt of David Zwally and both are members of the board of directors. Form 990, Part VI, Line 11b: Form 990 Review Process The Foundation provides the 990 to the board of directors for approval. Form 990, Part VI, Line 12c: Explanation of Monitoring and Enforcement of Conflicts Annual conflict of interest statements are circulated to all officers, directors, and key employees at the board of directors meeting. Management maintains signed copies of these statements for all such individuals to ensure compliance with this policy. Form 990, Part VI, Line 15a: Compensation Review & Approval Process - CEO, Top Management A written employee contract is established and approved by the board or compensation committee. Form 990, Part VI, Line 19: Other Organization Documents Publicly Available The Foundation makes its financial statements and 990 available to the public on its website, www.hdfoundation.org. The Foundation makes its governing documents and conflicts of interest policy available to the public upon request.