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        <FormAndLineReferenceDesc>Schedule J, Part I, Line 1a</FormAndLineReferenceDesc>
        <ExplanationTxt>The Ludwig Institute's travel policy allows first-class travel only under extraordinary circumstances. These include medical reasons or, for trips exceeding 5 hours, where business class or its equivalent is not offered. On occasions that call for the spouse or partner of members of the board or management to be invited to attend a Ludwig Institute meeting or function, expenses for these guests are reimbursed on the same conditions (including class of travel) as the member of the board or management as described in the foregoing travel policy.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule J, Part I, Line 3</FormAndLineReferenceDesc>
        <ExplanationTxt>Edward A. McDermott Jr. is employed by the Ludwig Group, Inc. which provides management and administrative services to the Ludwig Institute for Cancer Research Ltd, LICR Fund, Inc., and other organizations. The Ludwig Institute is invoiced by the Ludwig Group, Inc. for the provision of services based on the time records maintained by the Ludwig Group, Inc. The total level of compensation for Edward A. McDermott Jr. which is paid by the Ludwig Group, Inc. under an employment agreement, is set and approved by the compensation committee of the Ludwig Institute. In setting the level of compensation, the Ludwig Institute's compensation committee arranges for an independent compensation survey and comparison to compensation paid by other organizations using data available from the other organization's forms 990. Using this information the compensation committee sets the level of compensation and authorizes the Board of Directors of the Ludwig Group, Inc. to pay compensation at this level.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule J, Part I, Line 4b</FormAndLineReferenceDesc>
        <ExplanationTxt>Edward A. McDermott Jr. participated in a supplemental non qualified retirement plan maintained by the Ludwig Group, Inc., a related organization of the Institute. The purpose of the Ludwig Group, Inc.'s supplemental pension plan is to provide certain supplemental benefits to certain select management or highly compensated employees who are participants in the employee pension plan of the Ludwig Group, Inc. All benefits payable under the plan, which is intended to constitute both an unfunded excess benefit plan under section 3(36) of title I of the employee retirement income security act of 1974, as amended, ("ERISA"), and a non qualified, unfunded deferred compensation plan for a select group of management or highly compensated employees under ERISA, are payable from the general assets of the Ludwig Group, Inc. The Ludwig Group, Inc. may establish and fund a trust in order to aid it in providing benefits due under the plan. Within the amount disclosed on Part VII, Section A, Line 1a, Column F, USD 55,560 is attributable to this plan for Edward A. McDermott Jr.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule J, Part II, Column B</FormAndLineReferenceDesc>
        <ExplanationTxt>Column (B) includes compensation paid outside the U.S. to non-U.S. persons for which no Form W-2 or 1099-MISC has been issued.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Additional information to Part I, Line 25</FormAndLineReferenceDesc>
        <ExplanationTxt>Consistent with the Financial Statements prepared in accordance with the Swiss Code of Obligations, the non-cash figure consists mainly of stipends and grants and related laboratory consumables received directly by staff working in the Ludwig Institute's laboratories for the benefit of the Ludwig Institute. The basis for valuation is, where possible, the actual amount received by the person concerned or, where this information is not available, a reasonable estimate of the person's stipend or grant etc.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Form 990, Part III - Statement of program service accomplishments</FormAndLineReferenceDesc>
        <ExplanationTxt>Line 4a - Laboratory Research leading to clinical applications The Ludwig Institute for Cancer Research Ltd was founded 51 years ago as an international not-for-profit research institute dedicated to improving the understanding, prevention, detection and treatment of cancer. The Ludwig Institute's scientists conduct innovative basic research and facilitate the translation of promising discoveries related to cancer into applications for human benefit. Making meaningful advances that will ultimately transform care for cancer patients is central to the Ludwig Institute's mission. The Ludwig Institute engages leading scientists and clinicians in an integrated laboratory and clinical research effort to confront the global challenge of cancer. All laboratory research financed by the Ludwig Institute is carried out by its in-house research staff or through research collaborations involving Institute staff and external investigators. The Ludwig Institute has a staff of around 610 scientists, clinicians and support personnel as of December 31, 2021, located in four countries and focused on multiple aspects of cancer research. Approximately 80% of the total cost of the Ludwig Institute is funded by own resources. In addition to self-generated income from intellectual property, a significant amount is received from the LICR Fund, Inc., a Delaware supporting organization dedicated to maintaining an investment portfolio for this purpose. This funding setup gives Ludwig Institute investigators the freedom to tackle innovative long-term research and encourages and enables multidisciplinary teams of investigators to address significant and relatively complex challenges posed by cancer. The research activities of the Ludwig Institute, together with those of the Ludwig Centers established at six U.S. academic institutions with funding from a trust under the will of Daniel K. Ludwig are designated collectively as "Ludwig Cancer Research," an international community of distinguished scientists dedicated to studying cancer and advancing its prevention, diagnosis and treatment. The development, protection and licensing of intellectual property generated by research and technology development is fundamental to the Ludwig Institute's commitment to translate its discoveries for patient benefit. Income from these activities financed research expenditures amounting to USD 2.5 million in 2021. The Ludwig Institute also manages its IP and patents for public benefit. This means that the IP is made freely available to the academic research community. In 2021, Ludwig Institute Investigators published 263 primary research articles and 88 reviews, book chapters and commentaries. Progress was made in the study of tumor biology, cancer genomics, cancer prevention, the tumor micro-environment and tumor immunology. In 2021, eight new U.S. patents and two new European patents were issued, and 10 new U.S. applications and a further six new international patent applications were filed.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III - Statement of program service accomplishments</FormAndLineReferenceDesc>
        <ExplanationTxt>Line 4B - Clinical Research The analysis of patient samples and evaluation of potential therapies in trials is essential to understanding cancer and exploring the therapeutic potential of new discoveries. Recognizing this, the Ludwig Institute takes responsibility for the discovery continuum from the laboratory to the early phase clinical trials. The Ludwig Institute believes that the same systematic investigative rigor that yielded the laboratory discovery in the first place should be applied in early-phase clinical trials to assess a discovery's therapeutic potential. It has, therefore, committed the resources and marshalled the capabilities that allow it to evaluate its promising basic discoveries in human clinical studies. The Ludwig Institute has licensing agreements with biotechnology and pharmaceutical companies that allow it to obtain proprietary investigational reagents and evaluate whether these agents might complement the therapeutic potential of the Ludwig Institute's own discoveries. The Ludwig Institute's interactions with industry are designed to protect its tax-exempt status to ensure that its discoveries are actively pursued as prognostic, diagnostic or therapeutic agents for human benefit. Four Ludwig Institute-sponsored clinical trials were ongoing in 2021. These four trials, together with 21 previously completed studies, were supported by 11 active Ludwig Institute regulatory dossiers [eight Investigational New Drug (IND) applications (USA), one Drug Master File Notification (DMF) and two Clinical Trials Applications (CTA) in Switzerland and in the UK, respectively]. Over the year, the Ludwig Institute made no new regulatory submissions and 44 supplemental submissions to its active regulatory dossiers in three countries.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part IV - Checklist of required schedules</FormAndLineReferenceDesc>
        <ExplanationTxt>Line 12A and Part XII - Financial statements and reporting, Line 1 The Ludwig Institute prepared consolidated financial statements in accordance with Swiss GAAP FER. The Ludwig Institute prepared statutory financial statements in accordance with the Swiss Code of Obligations. The Ludwig Institute prepared branch financial statements in accordance with the Swiss Code of Obligations for the following branches: Brussels (Belgium), Oxford (United Kingdom) and San Diego (United States). The submitted return 990 is based on the statutory financial statements in accordance with the Swiss code of Obligations. The following accounting principles apply: - Contributions are accounted for on the cash basis - Interest is accounted for on the accrual basis - External funding received from any outside source, whether of a cash or a non-cash nature is recorded in the Ludwig Institute's books of account on receipt. External funding received is taken to income when the corresponding expenditure is incurred. Any unspent income is deferred to future accounting periods. External funding pledged, but not received where expenditure has incurred, is taken into account as income and is accounted for as a grants receivable pending receipt. - License fees and royalties are accounted for on the modified cash basis. - Acquisition costs for research equipment, costs for leasehold improvements and costs for other assets are fully expensed in the year of acquisition. The Ludwig Institute prepared financial statements in accordance with office of management and budget circular A-133 for the San Diego branch (United States). The Ludwig Institute maintains accounting ledgers for the head office / administration and the research locations of Brussels, Oxford, San Diego and Sao Paulo. Accounting ledgers are maintained in USD. When any expenditure / income or balance sheet transactions are recorded in the accounts, a non-USD currency is converted into USD reporting currency using the monthly exchange rate of the transaction month as published by the Swiss federal tax administration.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section A - Governing body and management, Line 2 Edward A. McDermott Jr., director and officer of the Ludwig Institute for Cancer Research Ltd, and Dr. Jonathan Skipper, officer of the Ludwig Institute for Cancer Research Ltd, also serve as officers and board members of Ludwig Technologies, Inc. Each of the members of the board of directors of the Ludwig Institute is also a member of the board of directors of the Fund.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section A - Governing body and management, Line 3 The Ludwig Group, Inc., a 100% subsidiary of the Ludwig Institute for Cancer Research Ltd, provides management and administrative services to the Ludwig Institute and related organizations, including personnel services and related facilities and equipment support, under formal service agreements with them. Edward A. McDermott Jr, director and president of the Ludwig Institute, is employed and compensated by the Ludwig Group, Inc. His compensation listed on the form 990, part VII is paid by the Ludwig Group, Inc. Edward A. McDermott Jr's services to Institute are billed to the Ludwig Institute by the Ludwig Group, Inc.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section A - Governing body and management, Line 6 The Ludwig Institute is organized as a Swiss not-for-profit organization. 49 of the shares are held by the trustees of the LICR Charitable trust, a Bermuda trust recognized by the IRS as an exempt supporting organization of the Ludwig Institute under section 501(c)(3) and 509(a)(3) of the Internal Revenue Code, whose primary purpose is to administer, devote and apply its assets to further the charitable purposes of the Ludwig Institute. Pursuant to the provisions of the Ludwig Institute's statutes, the members of the board of directors are no longer required to be shareholders. Three of the trustees of the LICR Charitable Trust are members of the Institute board of directors. One of the three trustees of the LICR Charitable Trust is also an officer of the Ludwig Institute. One share is held by the Swiss confederation.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, Management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section A - Governing body and management, Line 7a The statutes of the Ludwig Institute confer on its shareholders the authority to elect and remove members of the board of directors and participate in proceedings, deliberations elections and votes at shareholder meetings. The shares do not confer proprietary rights or any entitlement to any share of the Ludwig Institute's net income or capital or any other asset owned or managed by the Ludwig Institute. The Ludwig Institute's statutes prohibit the payment of any dividends or distribution of income or capital to the shareholders.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section A - Governing body and management, Line 7b The shareholders have the power to grant discharge to the members of the board of directors and the executive officers at the shareholders' annual meeting for their conduct of business. The annual financial statements are submitted to the shareholders by the board of directors for shareholder approval. The shareholders have the right to make resolutions in respect of mergers, dissolutions or liquidation of the company and of any change of the company's registered office.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section B - Policies, Line 11B The Ludwig Institute's form 990 is reviewed at several levels. The Ludwig Institute's Zurich office senior staff, the vice president, finance, located in New York and external tax counsel review the draft form 990. Following these reviews, the chairperson of the audit committee and the president of the Ludwig Institute review the draft return prior to presenting it to the audit committee for further review. The final draft of form 990 is then presented to the Ludwig Institute's board of directors prior to its submission to the Internal Revenue Service.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section B - Policies, Line 12c The Ludwig Institute has three conflict of interest policies - respectively for the board of directors, officers and staff. Annually all members of the board of directors, officers and staff are required to disclose any conflicts of interest. Board members and executive officers complete a conflict of interest questionnaire. All other staff members complete a confidential disclosure form. The completed questionnaires of the members of the board of directors and executive officers are reviewed by the compliance and risk officer. Those containing any disclosures or potential conflicts of interest are referred to the chairperson of the audit committee and, if appropriate, to the audit committee. At the same time it is confirmed to the audit committee chairperson that the other individuals had not reported any disclosures or potential conflicts of interest. Following this annual disclosure, if a conflict of interest is subsequently deemed to exist, it is the duty of the individual with the conflict to disclose it. For all cases where a conflict of interest exists, the matter is recorded in the minutes of the meeting of the audit committee or the board. Where the conflict concerns any board or committee member the individual(s) is (are) not permitted to participate in any vote or deliberation on the matter nor be counted in determining the existence of a quorum for the purposes of any action of the board or committee considering the matter. The annual disclosures by staff are reviewed by senior management and escalated as necessary. In addition, during the year, prior to involvement in activities that could be a potential or perceived conflict or interest, individuals are required to provide a written description of such activities to a committee of disinterested officers. Activities determined to be a conflict of interest that are not manageable may not be undertaken by the individual. For activities determined to be a conflict of interest that are manageable, details will be submitted to the audit committee of the Institute board of directors for approval.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section B - Policies, Line 15 The compensation of the members of the board of directors, the executive officers and former directors and officers who are retained as employees or consultants of the Ludwig Institute is subject to review by the Ludwig Institute's compensation committee, which consists of independent members of the board. The compensation reviewed includes the compensation of the chief executive officer, Edward A. McDermott Jr., who is employed by Ludwig Group, Inc., which provides management services to the Ludwig Institute. Independent compensation consultants provide comparability surveys to the committee. Organizations selected for peer analysis in the comparability surveys are intended to capture competitor organizations of similar size, revenue /operating budget and industry relevance to the Ludwig Institute. The studies last took place in Fall 2021 and are conducted approximately every three years. Minutes of the review and decisions made by the compensation committee are kept and, once approved by the committee at a subsequent meeting, are signed by the chairperson and the secretary to the board. The compensation committee's decisions are reported to the board of directors and recorded in the minutes of the board meetings, which are kept for all board meetings. Once approved by the board at a subsequent meeting, the minutes of meetings are signed by the chairperson and the secretary to the board.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Form 990, Part VI - Governance, management and disclosure</FormAndLineReferenceDesc>
        <ExplanationTxt>Section C - Disclosure, Line 19 The annual research highlights, the annual financial reports and the governing documents are available on the website www.ludwigcancerresearch.org under Disclosures and on request at the administrative offices in New York and Zurich, Switzerland.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Form 990, Part VII - Compensation of officers, directors, key employees</FormAndLineReferenceDesc>
        <ExplanationTxt>Section A - Officers, directors, trustees, key employees and highest compensated employees, Line 1a As part of the annual preparation of the form 990, all board of directors and executive officers provide an estimate of hours worked for the Ludwig Institute and the related organizations (see part VII for hours devoted to related organizations). The related organizations report the respective compensation figures to the Ludwig Institute and provide copies of the submitted W-2 returns / 1099 returns.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Form 990, Part XI - Reconciliation of net assets, Line 9</FormAndLineReferenceDesc>
        <ExplanationTxt>Other changes in net assets Net loss on foreign exchange due to operations $ (681,861) Net foreign exchange gain on capital and reserve $ 342,909 ------------ Net loss $ (338,952)</ExplanationTxt>
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          <BusinessNameLine1Txt>Ludwig Inst</BusinessNameLine1Txt>
        </DirectControllingEntityName>
        <EntityTypeTxt>C Corp</EntityTypeTxt>
        <ShareOfTotalIncomeAmt>7375230</ShareOfTotalIncomeAmt>
        <ShareOfEOYAssetsAmt>28540428</ShareOfEOYAssetsAmt>
        <OwnershipPct>1.00000</OwnershipPct>
        <ControlledOrganizationInd>true</ControlledOrganizationInd>
      </IdRelatedOrgTxblCorpTrGrp>
      <IdRelatedOrgTxblCorpTrGrp>
        <RelatedOrganizationName>
          <BusinessNameLine1Txt>The Ludwig Group Inc</BusinessNameLine1Txt>
        </RelatedOrganizationName>
        <USAddress>
          <AddressLine1Txt>600 Third Avenue 32nd Floor</AddressLine1Txt>
          <CityNm>New York</CityNm>
          <StateAbbreviationCd>NY</StateAbbreviationCd>
          <ZIPCd>10016</ZIPCd>
        </USAddress>
        <EIN>132808920</EIN>
        <PrimaryActivitiesTxt>Admin service</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>DE</LegalDomicileStateCd>
        <DirectControllingEntityName>
          <BusinessNameLine1Txt>UTI</BusinessNameLine1Txt>
        </DirectControllingEntityName>
        <EntityTypeTxt>C Corp</EntityTypeTxt>
        <ShareOfTotalIncomeAmt>7790407</ShareOfTotalIncomeAmt>
        <ShareOfEOYAssetsAmt>17756605</ShareOfEOYAssetsAmt>
        <OwnershipPct>1.00000</OwnershipPct>
        <ControlledOrganizationInd>true</ControlledOrganizationInd>
      </IdRelatedOrgTxblCorpTrGrp>
      <IdRelatedOrgTxblCorpTrGrp>
        <RelatedOrganizationName>
          <BusinessNameLine1Txt>Ludwig Technologies Inc</BusinessNameLine1Txt>
        </RelatedOrganizationName>
        <USAddress>
          <AddressLine1Txt>600 Third Avenue 32nd Floor</AddressLine1Txt>
          <CityNm>New York</CityNm>
          <StateAbbreviationCd>NY</StateAbbreviationCd>
          <ZIPCd>10016</ZIPCd>
        </USAddress>
        <EIN>273166967</EIN>
        <PrimaryActivitiesTxt>Holding Co</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>DE</LegalDomicileStateCd>
        <DirectControllingEntityName>
          <BusinessNameLine1Txt>Ludwig Inst</BusinessNameLine1Txt>
        </DirectControllingEntityName>
        <EntityTypeTxt>C Corp</EntityTypeTxt>
        <ShareOfTotalIncomeAmt>0</ShareOfTotalIncomeAmt>
        <ShareOfEOYAssetsAmt>741</ShareOfEOYAssetsAmt>
        <OwnershipPct>1.00000</OwnershipPct>
        <ControlledOrganizationInd>true</ControlledOrganizationInd>
      </IdRelatedOrgTxblCorpTrGrp>
      <ReceiptOfIntAnntsRntsRyltsInd>true</ReceiptOfIntAnntsRntsRyltsInd>
      <GiftGrntOrCapContriToOthOrgInd>false</GiftGrntOrCapContriToOthOrgInd>
      <GiftGrntCapContriFromOthOrgInd>true</GiftGrntCapContriFromOthOrgInd>
      <LoansOrGuaranteesToOtherOrgInd>true</LoansOrGuaranteesToOtherOrgInd>
      <LoansOrGuaranteesFromOthOrgInd>false</LoansOrGuaranteesFromOthOrgInd>
      <DivRelatedOrganizationInd>false</DivRelatedOrganizationInd>
      <AssetSaleToOtherOrgInd>true</AssetSaleToOtherOrgInd>
      <AssetPurchaseFromOtherOrgInd>false</AssetPurchaseFromOtherOrgInd>
      <AssetExchangeInd>false</AssetExchangeInd>
      <RentalOfFacilitiesToOthOrgInd>false</RentalOfFacilitiesToOthOrgInd>
      <RentalOfFcltsFromOthOrgInd>false</RentalOfFcltsFromOthOrgInd>
      <PerformOfServicesForOthOrgInd>false</PerformOfServicesForOthOrgInd>
      <PerformOfServicesByOtherOrgInd>true</PerformOfServicesByOtherOrgInd>
      <SharingOfFacilitiesInd>true</SharingOfFacilitiesInd>
      <PaidEmployeesSharingInd>false</PaidEmployeesSharingInd>
      <ReimbursementPaidToOtherOrgInd>true</ReimbursementPaidToOtherOrgInd>
      <ReimbursementPaidByOtherOrgInd>true</ReimbursementPaidByOtherOrgInd>
      <TransferToOtherOrgInd>false</TransferToOtherOrgInd>
      <TransferFromOtherOrgInd>false</TransferFromOtherOrgInd>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>LICR Fund Inc</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>a</TransactionTypeTxt>
        <InvolvedAmt>276473</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>CASH</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>LICR Fund Inc</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>c</TransactionTypeTxt>
        <InvolvedAmt>45000000</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>CASH</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>LICR Fund Inc</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>d,g</TransactionTypeTxt>
        <InvolvedAmt>24000000</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>CASH</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>The Ludwig Group Inc</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>n</TransactionTypeTxt>
        <InvolvedAmt>740723</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>INVOICE AMOUNTS</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>The Ludwig Group Inc</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>m</TransactionTypeTxt>
        <InvolvedAmt>2249424</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>INVOICE AMOUNTS</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>The Ludwig Group Inc</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>p</TransactionTypeTxt>
        <InvolvedAmt>1784255</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>INVOICE AMOUNTS</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>LICR Fund Inc</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>q</TransactionTypeTxt>
        <InvolvedAmt>55784</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>INVOICE AMOUNTS</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Part II, Column 2B - Description of main activity related tax exempt org</FormAndLineReferenceDesc>
        <ExplanationTxt>Tax exempt organizations LICR Fund, Inc. is a Delaware not-for-profit corporation and a supporting organization of the Ludwig Institute, which provides financial support for the Ludwig Institute's conduct of medical research activities. LICR Charitable Trust is a Bermudian trust whose mission is to maintain oversight and control of the management of the Ludwig Institute, including election of the Institute's board of directors.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Part V, Line 1a - Receipt of interest from a controlled entity</FormAndLineReferenceDesc>
        <ExplanationTxt>The loan from Ludwig Institute to LICR Fund constitutes interorganizational indebtedness that does not give rise to unrelated debt-financed income under Section 514 of the Code.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleR>
  </ReturnData>
</Return>
