2022-11-04T12:12:33-05:00 2021-12-31 910189318 MOSS ADAMS LLP 4747 EXECUTIVE DR SUITE 1300 SAN DIEGO CA 92121 990 2021-01-01 237203666 THE J DAVID GLADSTONE INSTITUTES JDAV 4157342000 1650 OWENS STREET SAN FRANCISCO CA 94158 MICHELLE SIBLY VICE PRESIDENT, FINANCE 4157342000 2022-11-01 1 MICHELLE SIBLY 999009999 PATRICIA J MAYER P00188643 8586271400 3 AAL1 IAL1 2021 2022-09-23 18:48:47Z ROBERT OBANA 1650 OWENS STREET SAN FRANCISCO CA 94158 162323985 0 X WWW.GLADSTONEINSTITUTES.ORG X 1972 CA TO DRIVE A NEW ERA OF DISCOVERY IN DISEASE ORIENTED SCIENCE AND TO MENTOR TOMORROW'S LEADERS IN AN INSPIRING AND DIVERSE ENVIRONMENT. 3 0 530 85 -294738 0 8871876 70616690 58349338 65809447 16287063 6412478 766388 211364 84274665 143049979 0 0 0 0 49154685 55555884 0 0 1407194 44358074 47461466 93512759 103017350 -9238094 40032629 318407379 367466101 197575119 191340783 120832260 176125318 X TO DRIVE A NEW ERA OF DISCOVERY IN DISEASE ORIENTED SCIENCE AND TO MENTOR TOMORROW'S LEADERS IN AN INSPIRING AND DIVERSE ENVIRONMENT. 0 0 18603918 14195639 THE INSTITUTE OF VIROLOGY HAS MADE SIGNIFICANT CONTRIBUTIONS TO FIGHTING HIV/AIDS, PAVING THE WAY FOR MANY MEDICATIONS CURRENTLY IN USE AND LEADING TO A GLOBAL AND GROUNDBREAKING EFFORT IN HIV PREVENTION. RESEARCHERS CONTINUE TO EXPLORE THE BIOLOGICAL BASIS FOR HIV LATENCY, WHICH REPRESENTS THE GREATEST BARRIER TO A CURE. THE INSTITUTE HAS ALSO EXPANDED ITS FOCUS TO STUDY OTHER VIRUSES AND INFECTIOUS DISEASES, AND LOOK FOR UNIQUE STRATEGIES TO TREAT MULTIPLE VIRUSES AT ONCE. 16702894 9983637 THE INSTITUTE OF CARDIOVASCULAR DISEASE LEVERAGES IMPORTANT GENETIC, DEVELOPMENTAL, CHEMICAL, BIOLOGICAL SYSTEMS, COMPUTATIONAL, AND ENGINEERING APPROACHES TO STUDY HEART DISEASE AND STEM CELL BIOLOGY. 37018831 31618434 THE INSTITUTE OF NEUROLOGICAL DISEASE MAINTAINS A STRONG FOCUS ON NEURODEGENERATIVE AND NEUROINFLAMMATORY DISEASES, INCLUDING ALZHEIMER'S DISEASE AND OTHER DEMENTIAS, PARKINSON'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS (ALS), AND MULTIPLE SCLEROSIS. THE INVESTIGATORS ARE SEARCHING FOR COMMON THREADS THAT WILL ALLOW THEM TO IDENTIFY THERAPEUTIC INTERVENTIONS THAT MIGHT BENEFIT MULTIPLE CONDITIONS. THEY ARE USING UNCONVENTIONAL APPROACHES TO IDENTIFY SUCH MULTI-FACETED SOLUTIONS, WHILE ALSO LEVERAGING CAPABILITIES IN REGENERATIVE AND PERSONALIZED MEDICINE. 14942919 10011737 THE GLADSTONE INSTITUTE OF DATA SCIENCE AND BIOTECHNOLOGY INVESTS IN TALENT TO CREATE NEW WAYS TO ANALYZE AND INTEGRATE DATASETS, INCLUDING MACHINE LEARNING APPROACHES THAT LEVERAGE THE RAPID ADVANCES IN ARTIFICIAL INTELLIGENCE. IT WILL BE THE HOME FOR DEVELOPMENT OF NEW TECHNOLOGIES THAT CAN ACCELERATE DISCOVERY IN ALL AREAS OF INVESTIGATION AT GLADSTONE. GLADSTONE - UCSF INSTITUTE OF GENOMIC IMMUNOLOGY BLENDS THE LATEST GENOMICS AND GENOME ENGINEERING TECHNOLOGIES WITH IMMUNOLOGY RESEARCH TO ENGINEER THE HUMAN IMMUNE SYSTEM FOR THERAPEUTIC BENEFIT. 14942919 10011737 87268562 1 1 0 0 0 0 0 0 0 1 1 1 0 0 1 1 0 1 0 0 1 0 0 0 0 0 0 0 0 1 0 0 0 1 0 0 0 0 1 0 0 0 0 1 1 1 0 0 1 98 0 1 530 1 1 1 0 0 0 0 0 0 0 0 0 0 0 X 3 0 0 0 0 0 0 0 1 1 1 0 0 1 1 1 1 1 1 1 1 0 CA X MICHELLE S SIBLY 4157342000 1650 OWENS STREET SAN FRANCISCO CA 94158 ANDREW S GARB TRUSTEE 3.00 0.00 X 425000 0 0 NICHOLAS J SIMON TRUSTEE 3.00 0.00 X 425000 0 0 WILLIAM PRICE TRUSTEE 3.00 0.00 X 100000 0 0 DEEPAK SRIVASTAVA PRESIDENT 40.00 1.00 X 1005808 0 77666 ROBERT OBANA COO 40.00 0.00 X 538250 0 68517 ALEX MARSON DIRECTOR 40.00 0.00 X 510740 0 38757 BENOIT BRUNEAU DIRECTOR 40.00 0.00 X 496795 0 77666 KATHERINE POLLARD DIRECTOR 40.00 0.00 X 458517 0 77666 LENNART MUCKE DIRECTOR 40.00 0.00 X 559420 0 55337 MELANIE OTT DIRECTOR 40.00 0.00 X 480052 0 77666 STEVEN M FINKBEINER DIRECTOR 40.00 0.00 X 512829 0 77666 WARNER GREENE DIRECTOR 40.00 0.00 X 512441 0 68517 JENNIFER CROSBY VP OF PEOPLE SERVICES 40.00 0.00 X 409055 0 34166 LEOR WEINBERGER SR. 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RESEARCH WILL BE PERFORMED ON THESE PROJECTS OVER THE NEXT FEW YEARS. PERMANENTLY RESTRICTED FUND EARNINGS WILL BE SPENT ON SCIENTIFIC RESEARCH AND ADMINISTRATION. PART X, LINE 2: THE INSTITUTES HAS BEEN GRANTED EXEMPTION FROM INCOME TAXES UNDER SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE AND SECTION 23701D OF THE CALIFORNIA REVENUE AND TAXATION CODE. THE INSTITUTES IS SUBJECT TO UNRELATED BUSINESS INCOME TAX ON CERTAIN RENTAL TRANSACTIONS AND INCOME FROM ALTERNATIVE INVESTMENTS. FOR THE YEARS ENDED DECEMBER 31, 2021 AND 2020, THE INSTITUTES HAD APPROXIMATELY $11,587,000 AND $11,535,000 OF CUMULATIVE TAXABLE LOSSES, RESPECTIVELY. SINCE MANAGEMENT BELIEVES IT IS UNLIKELY THERE WILL BE FUTURE INCOME TO OFFSET THESE LOSSES, A VALUATION ALLOWANCE HAS BEEN REFLECTED AGAINST THE FULL BALANCE. THE INSTITUTES FILES AN EXEMPT ORGANIZATION RETURN AND APPLICABLE UNRELATED BUSINESS INCOME TAX RETURNS IN THE U.S. FEDERAL JURISDICTION AND WITH THE FRANCHISE TAX BOARD IN THE STATE OF CALIFORNIA. THE INSTITUTES HAD NO UNRECOGNIZED TAX BENEFITS AT DECEMBER 31, 2021 AND 2020. 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PART I, LINE 7 NONDISCRETIONARY BONUS PAYMENTS WERE PAID BASED ON PERSONS MEETING GOALS SET BY AND APPROVED BY TRUSTEES. DEEPAK SRIVASTAVA PRESIDENT HOUSING X 820000 675000 0 1 1 ALEX MARSON DIRECTOR HOUSING X 500000 400000 0 1 1 1075000 X 3 2500317 FMV 0 0 1 0 PART I, COLUMN (B): THE NUMBERS REPORTED IN PART I, COLUMN (B) REPRESENT THE NUMBER OF CONTRIBUTIONS. FORM 990, PART VI, SECTION A, LINE 7B THE SUPERIOR COURT OF CALIFORNIA'S APPROVAL IS REQUIRED FOR THE ELECTION AND REMOVAL OF TRUSTEES. FORM 990, PART VI, SECTION B, LINE 11B THE FORM 990 AND ITS RELATED SCHEDULES WERE GIVEN TO THE TRUSTEES FOR REVIEW AND APPROVAL PRIOR TO FILING. FORM 990, PART VI, SECTION B, LINE 12C THE J. DAVID GLADSTONE INSTITUTES REQUIRES THAT EACH OFFICER, DIRECTOR, TRUSTEE AND KEY EMPLOYEE COMPLETE A CONFLICT OF INTEREST REPORT AND REPORT ANY CONFLICT HE/SHE MAY HAVE. ANY CONFLICTS THAT ARISE DURING THE YEAR ARE REQUIRED TO BE REPORTED TO THE EXECUTIVE DIRECTOR AND THE TRUSTEES IMMEDIATELY. IN THE EVENT THAT A CONFLICT DOES ARISE THAT INDIVIDUAL IS PROHIBITED FROM PARTICIPATING IN THE GOVERNING BODY'S DELIBERATIONS AND DECISIONS IN THAT TRANSACTION. FORM 990, PART VI, SECTION B, LINE 15 THE ATTORNEY GENERAL FOR THE STATE OF CALIFORNIA IS ADVISED OF TRUSTEE COMPENSATION AND THE STATE OF CALIFORNIA SUPERIOR COURT REVIEWS AND APPROVES THE COMPENSATION. AN EXECUTIVE COMPENSATION REPORT IS COMPLETED EACH YEAR BY AN INDEPENDENT CONSULTING FIRM FROM SALARY SURVEYS, NON-PROFIT FORM 990'S AND OTHER SOURCES ON ORGANIZATIONS THAT ARE COMPARABLE IN SIZE AND COMPLEXITY TO THE INSTITUTES. THE 2021 REPORT WAS COMPLETED 01/06/21. THE PRESIDENT AND DIRECTORS' COMPENSATION IS APPROVED BY THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO VICE DEAN EACH YEAR. 2021 SALARIES WERE APPROVED ON 01/06/21. THE INSTITUTES' PRESIDENT AND DIRECTORS UTILIZE SIMILAR RESOURCES AS GUIDELINES WHEN APPROVING COMPENSATION FOR THE INSTITUTES' KEY EMPLOYEES, OTHER OFFICERS AND DIRECT REPORTS. COMPENSATION WAS LAST APPROVED ON 01/06/21. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION MAKES ITS FINANCIAL STATEMENTS, CONFLICT OF INTEREST POLICY AND ORGANIZATIONAL DOCUMENTS AVAILABLE TO THE PUBLIC UPON REQUEST. FORM 990, PART IX, LINE 11G SERVICE CONTRACTS: PROGRAM SERVICE EXPENSES 1,043,584. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 1,043,584. SUBCONTRACTS: PROGRAM SERVICE EXPENSES 5,210,064. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 5,210,064. OUTSIDE LABORATORY SERVICES: PROGRAM SERVICE EXPENSES 966,347. MANAGEMENT AND GENERAL EXPENSES 0. FUNDRAISING EXPENSES 0. TOTAL EXPENSES 966,347. OTHER SERVICES: PROGRAM SERVICE EXPENSES 3,825,720. MANAGEMENT AND GENERAL EXPENSES 669,044. FUNDRAISING EXPENSES 54,046. TOTAL EXPENSES 4,548,810. FORM 990, PART XI, LINE 9: K-1 PASSTHROUGH 294,738. 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