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        <FormAndLineReferenceDesc>FORM 990, PAGE 2, PART III, LINE 4A</FormAndLineReferenceDesc>
        <ExplanationTxt>PATIENT ADVOCACY AND EDUCATION HEALTHTREE FOUNDATION HAS A DEEP SET OF RICH PROGRAMS AND RESOURCES TO PROVIDE ADVOCACY AND EDUCATION FOR BLOOD CANCER PATIENTS. WE UNDERSTAND THAT HAVING AND LIVING WITH A DISEASE REQUIRES DISEASE-SPECIFIC SUPPORT TO MAKE IT TRULY USEFUL. OUR PROGRAMS FOR PATIENT ADVOCACY AND EDUCATION IN MULTIPLE MYELOMA AND AML INCLUDE: HEALTHTREE COMMUNITY: A NEWS WEBSITE IN PATIENT-FRIENDLY LANGUAGE, A SPECIALIST DIRECTORY, A JOURNALING FEATURE, REGULAR WEBINAR EVENTS WITH MEDICAL EXPERTS IN TOPIC- BASED OR GEOGRAPHIC CHAPTERS, AND AN UPCOMING SOCIAL MEDIA NETWORK FOR A COMPREHENSIVE PATIENT COMMUNITY EXPERIENCE. HEALTHTREE UNIVERSITY: AN ONLINE, ANIMATED VIDEO CURRICULUM WITH DOZENS OF COURSES AND OF HUNDREDS OF LESSONS TAUGHT BY MYELOMA AND AML EXPERTS. HTU IS ONE OF OUR MOST POPULAR PROGRAMS AND CAN HELP A NEWLY DIAGNOSED PATIENT GET UP-TO-SPEED ON EVERYTHING INCLUDING BASICS, HOW TO BUILD AND NAVIGATE YOUR HEALTHCARE TEAM, GENETICS, UNDERSTANDING LABS, "KNOW YOUR THERAPY- AND COMPLEX TOPICS LIKE TREATMENT CHOICES. HEALTHTREE ROUND TABLES: LIVE OR ONLINE MEETINGS WITH A PANEL OF MULTIPLE MYELOMA AND AML EXPERTS WHO COVER TOPICS RANGING FROM NEWLY DIAGNOSED TESTING TO DECISION-MAKING AT RELAPSE. HEALTHTREE PODCAST: AN HOUR-LONG PODCAST INTERVIEWING MULTIPLE MYELOMA AND AML EXPERTS WITH A FOCUS ON CLINICAL TRIALS SO PATIENTS UNDERSTAND WHAT THE CLINICAL TRIALS ARE HOPING TO ACCOMPLISH AND WHY AND HOW PATIENTS SHOULD JOIN. HEALTHTREE COACH: HEALTHTREE COACHES ARE EXPERIENCED PATIENTS OR CAREGIVERS WHO VOLUNTEER THEIR TIME TO SUPPORT PATIENTS IN NAVIGATING THEIR CARE. MYELOMA PATIENTS CAN CHOOSE FROM OVER 200 COACHES TO OBTAIN TEMPORARY OR LONG-TERM SUPPORT WITH ONE-ON-ONE HELP. HEALTHTREE MOVES: WE PROVIDE AN IPHONE OR ANDROID PHONE APP CALLED HEALTHTREE MOVES TO FACILITATE GROUP FITNESS CHALLENGES AS WELL AS A 5K AND 1 MILE RACE SERIES TO PROVIDE A FUN FITNESS ENVIRONMENT THAT BUILDS AND ENGAGE THE PATIENT COMMUNITY. HEALTHTREE REACH: WE AIM TO REACH ALL MULTIPLE MYELOMA PATIENTS AND PROVIDE TAILORED SERVICES TO SPANISH-SPEAKING, BLACK, RURAL AND OTHER PATIENTS WITH UNIQUE NEEDS. ADDITIONAL BLOOD CANCERS WILL BE SUPPORTED IN FUTURE YEARS.</ExplanationTxt>
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        <FormAndLineReferenceDesc>FORM 990, PAGE 2, PART III, LINE 4B</FormAndLineReferenceDesc>
        <ExplanationTxt>HEALTHTREE RESEARCH IN ADDITION TO SUPPORTING PATIENTS THROUGH OUR ADVOCACY AND EDUCATION EFFORTS, HEALTHTREE FOUNDATION IS RELENTLESS IN MOVING US CLOSER TO A MYELOMA AND AML CURE. WE BUILT A UNIQUE PATIENT DATA PORTAL CALLED HEALTHTREE CURE HUB THAT NOT ONLY SUPPORTS PATIENTS IN NAVIGATING THEIR DISEASE, IT CAN ALSO FACILITATE INVESTIGATOR-LED RESEARCH TO HELP THEM COME TO FASTER CONCLUSIONS USING REAL WORLD EVIDENCE. HEALTHTREE CLINICAL TRIAL FINDER: AN EASIER WAY TO FIND AND JOIN A MULTIPLE MYELOMA OR AML CLINICAL TRIAL. WITH ADVANCED FILTERING, FINDING CLINICAL TRIALS FOR A SPECIFIC TARGET, PATIENTS TYPE, GENETIC TYPE OR LOCATION IS SIGNIFICANTLY EASIER. WHEN PATIENTS JOIN CLINICAL TRIALS IN GREATER NUMBERS, THEY CAN HELP ACCELERATE FASTER CURES. HEALTHTREE CURE HUB: A PATIENT DATA PORTAL WHERE PATIENTS CAN LINK AND AGGREGATE THEIR MEDICAL RECORDS IN ORDER TO RECEIVE HELP NAVIGATING THEIR DISEASE (LAB TRACKING, TREATMENT TRACKING, FINDING A "TWIN- AND VIEWING SIDE EFFECT SOLUTIONS). PATIENTS CAN ALSO BECOME PART OF THE CURE BY CONTRIBUTING TO RESEARCH THROUGH SURVEYS OR STUDIES. PATIENT PARTICIPATION HELPS US USE REAL WORLD EVIDENCE TO ACCELERATE RESEARCHER PROJECTS AND PROVIDES INVESTIGATORS ACCESS TO ANONYMIZED DATA FOR FREE, SAVING THEM YEARS AND HUNDREDS OF THOUSANDS OF DOLLARS TO FACILITATE THEIR WORK. TO DATE, OVER 10,500 MYELOMA PATIENTS HAVE JOINED HEALTHTREE CURE HUB. IN 2021 WE FACILITATED 10 RESEARCH PROJECTS IN MULTIPLE MYELOMA AND PUBLISHED AN INTRODUCTORY PAPER ABOUT HEALTHTREE CURE HUB IN THE JOURNAL OF CLINICAL ONCOLOGY. IN THE FUTURE, HEALTHTREE CURE HUB WILL BE INTRODUCED IN AML AND OTHER BLOOD CANCERS.</ExplanationTxt>
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        <FormAndLineReferenceDesc>FORM 990, PAGE 6, PART VI, LINE 11B</FormAndLineReferenceDesc>
        <ExplanationTxt>A COPY OF THE RETURN IS PROVIDED TO BOARD MEMBERS VIA EMAIL.</ExplanationTxt>
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        <ExplanationTxt>THE COMPENSATION COMMITTEE FOLLOWS THE REBUTTABLE PRESUMPTION OF REASONABLENESS PROCEDURE DESCRIBED IN IRS REGULATIONS SECTION 53.4958-6(C) WHEN SETTING COMPENSATION FOR THE POSITION OF PRESIDENT/CEO AND UTILIZES COMPARABLE NON-PROFIT SALARY DATA FOR ESTABLISHING COMPENSATION LEVELS.</ExplanationTxt>
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