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      <Form990PartVIISectionAGrp>
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        <PersonNm>TRACEY L HEATHER</PersonNm>
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      <Form990PartVIISectionAGrp>
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      <Form990PartVIISectionAGrp>
        <PersonNm>KATHRYN J WATSON-FEINER</PersonNm>
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            <BusinessNameLine1Txt>NOHA LIM</BusinessNameLine1Txt>
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          <USAddress>
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      <ContractorCompensationGrp>
        <ContractorName>
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          <USAddress>
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      <ContractorCompensationGrp>
        <ContractorName>
          <BusinessName>
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          <USAddress>
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      <ContractorCompensationGrp>
        <ContractorName>
          <PersonNm>SURESH GADAMSETTY</PersonNm>
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          <USAddress>
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        <ServicesDesc>SOFTWARE DEVELOPMENT AND TECHNICAL ASSIS</ServicesDesc>
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      <ContractorCompensationGrp>
        <ContractorName>
          <PersonNm>STEFFANIE GOODMAN</PersonNm>
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        <ContractorAddress>
          <USAddress>
            <AddressLine1Txt>2030 FELL STREET 2</AddressLine1Txt>
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        </ContractorAddress>
        <ServicesDesc>CONSULTING SERVICE</ServicesDesc>
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      <CntrctRcvdGreaterThan100KCnt>11</CntrctRcvdGreaterThan100KCnt>
      <GovernmentGrantsAmt>32977715</GovernmentGrantsAmt>
      <AllOtherContributionsAmt>584474</AllOtherContributionsAmt>
      <NoncashContributionsAmt>23400</NoncashContributionsAmt>
      <TotalContributionsAmt>33562189</TotalContributionsAmt>
      <ProgramServiceRevenueGrp>
        <Desc>CLINICAL TRIAL CONTRACTS</Desc>
        <BusinessCd>541511</BusinessCd>
        <TotalRevenueColumnAmt>22236632</TotalRevenueColumnAmt>
        <RelatedOrExemptFuncIncomeAmt>22236632</RelatedOrExemptFuncIncomeAmt>
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      <ProgramServiceRevenueGrp>
        <Desc>CONSULTING AND RESEARCH CONTRACTS</Desc>
        <BusinessCd>541511</BusinessCd>
        <TotalRevenueColumnAmt>312140</TotalRevenueColumnAmt>
        <RelatedOrExemptFuncIncomeAmt>312140</RelatedOrExemptFuncIncomeAmt>
      </ProgramServiceRevenueGrp>
      <TotalProgramServiceRevenueAmt>22548772</TotalProgramServiceRevenueAmt>
      <InvestmentIncomeGrp>
        <TotalRevenueColumnAmt>31363</TotalRevenueColumnAmt>
        <ExclusionAmt>31363</ExclusionAmt>
      </InvestmentIncomeGrp>
      <TotalRevenueGrp>
        <TotalRevenueColumnAmt>56142324</TotalRevenueColumnAmt>
        <RelatedOrExemptFuncIncomeAmt>22548772</RelatedOrExemptFuncIncomeAmt>
        <UnrelatedBusinessRevenueAmt>0</UnrelatedBusinessRevenueAmt>
        <ExclusionAmt>31363</ExclusionAmt>
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      <GrantsToDomesticOrgsGrp>
        <TotalAmt>25791</TotalAmt>
        <ProgramServicesAmt>25791</ProgramServicesAmt>
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      <CompCurrentOfcrDirectorsGrp>
        <TotalAmt>605994</TotalAmt>
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        <ManagementAndGeneralAmt>792711</ManagementAndGeneralAmt>
        <FundraisingAmt>194175</FundraisingAmt>
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      <PensionPlanContributionsGrp>
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        <FundraisingAmt>4573</FundraisingAmt>
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        <TotalAmt>1138755</TotalAmt>
        <ProgramServicesAmt>1002996</ProgramServicesAmt>
        <ManagementAndGeneralAmt>108880</ManagementAndGeneralAmt>
        <FundraisingAmt>26879</FundraisingAmt>
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      <PayrollTaxesGrp>
        <TotalAmt>562789</TotalAmt>
        <ProgramServicesAmt>495695</ProgramServicesAmt>
        <ManagementAndGeneralAmt>53810</ManagementAndGeneralAmt>
        <FundraisingAmt>13284</FundraisingAmt>
      </PayrollTaxesGrp>
      <FeesForServicesLegalGrp>
        <TotalAmt>92525</TotalAmt>
        <ProgramServicesAmt>88391</ProgramServicesAmt>
        <ManagementAndGeneralAmt>3118</ManagementAndGeneralAmt>
        <FundraisingAmt>1016</FundraisingAmt>
      </FeesForServicesLegalGrp>
      <FeesForServicesAccountingGrp>
        <TotalAmt>319638</TotalAmt>
        <ProgramServicesAmt>305355</ProgramServicesAmt>
        <ManagementAndGeneralAmt>10771</ManagementAndGeneralAmt>
        <FundraisingAmt>3512</FundraisingAmt>
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        <TotalAmt>4288909</TotalAmt>
        <ProgramServicesAmt>4106248</ProgramServicesAmt>
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        <FundraisingAmt>45597</FundraisingAmt>
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      <InformationTechnologyGrp>
        <TotalAmt>5826653</TotalAmt>
        <ProgramServicesAmt>5798589</ProgramServicesAmt>
        <ManagementAndGeneralAmt>13780</ManagementAndGeneralAmt>
        <FundraisingAmt>14284</FundraisingAmt>
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      <OccupancyGrp>
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        <ProgramServicesAmt>273383</ProgramServicesAmt>
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      <TravelGrp>
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        <ProgramServicesAmt>16686</ProgramServicesAmt>
        <ManagementAndGeneralAmt>1238</ManagementAndGeneralAmt>
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      <DepreciationDepletionGrp>
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        <ProgramServicesAmt>64374</ProgramServicesAmt>
        <ManagementAndGeneralAmt>1290</ManagementAndGeneralAmt>
        <FundraisingAmt>419</FundraisingAmt>
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      <InsuranceGrp>
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        <ProgramServicesAmt>67928</ProgramServicesAmt>
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      <OtherExpensesGrp>
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        <TotalAmt>15223948</TotalAmt>
        <ProgramServicesAmt>15223948</ProgramServicesAmt>
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      <OtherExpensesGrp>
        <Desc>PROGRAM MANAGEMENT</Desc>
        <TotalAmt>4520577</TotalAmt>
        <ProgramServicesAmt>4519887</ProgramServicesAmt>
        <ManagementAndGeneralAmt>690</ManagementAndGeneralAmt>
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      <OtherExpensesGrp>
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        <ProgramServicesAmt>2507660</ProgramServicesAmt>
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      <OtherExpensesGrp>
        <Desc>OTHER PROGRAM EXPENSES</Desc>
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        <ProgramServicesAmt>56724</ProgramServicesAmt>
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      <AllOtherExpensesGrp>
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        <ProgramServicesAmt>-4560</ProgramServicesAmt>
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      <TotalFunctionalExpensesGrp>
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        <ProgramServicesAmt>42230475</ProgramServicesAmt>
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        <EOYAmt>1775471</EOYAmt>
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      <AccountsReceivableGrp>
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        <EOYAmt>2884</EOYAmt>
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      <PrepaidExpensesDefrdChargesGrp>
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      <LandBldgEquipBasisNetGrp>
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        <EOYAmt>210502</EOYAmt>
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      <InvestmentsPubTradedSecGrp>
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        <EOYAmt>7666055</EOYAmt>
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        <EOYAmt>0</EOYAmt>
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      <TotalAssetsGrp>
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        <EOYAmt>64443428</EOYAmt>
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      <AccountsPayableAccrExpnssGrp>
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        <EOYAmt>25408456</EOYAmt>
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        <EOYAmt>33840706</EOYAmt>
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        <EOYAmt>28731090</EOYAmt>
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      <DonorRestrictionNetAssetsGrp>
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        <EOYAmt>1871632</EOYAmt>
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      <TotalNetAssetsFundBalanceGrp>
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        <EOYAmt>30602722</EOYAmt>
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      <TotLiabNetAssetsFundBalanceGrp>
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        <EOYAmt>64443428</EOYAmt>
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      <InfoInScheduleOPartXIInd>X</InfoInScheduleOPartXIInd>
      <ReconcilationRevenueExpnssAmt>12386762</ReconcilationRevenueExpnssAmt>
      <NetUnrlzdGainsLossesInvstAmt>42535</NetUnrlzdGainsLossesInvstAmt>
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      <MethodOfAccountingAccrualInd>X</MethodOfAccountingAccrualInd>
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    <IRS990ScheduleA documentId="RetDoc1039100001">
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        <CurrentTaxYearMinus3YearsAmt>1203352</CurrentTaxYearMinus3YearsAmt>
        <CurrentTaxYearMinus2YearsAmt>1876103</CurrentTaxYearMinus2YearsAmt>
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        <CurrentTaxYearMinus1YearAmt>12652517</CurrentTaxYearMinus1YearAmt>
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        <CurrentTaxYearMinus1YearAmt>87600</CurrentTaxYearMinus1YearAmt>
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        <ContributorNum>RESTRICTED</ContributorNum>
        <ContributorBusinessName>
          <BusinessNameLine1>RESTRICTED</BusinessNameLine1>
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        <ContributorUSAddress>
          <AddressLine1>RESTRICTED</AddressLine1>
          <AddressLine2>RESTRICTED</AddressLine2>
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          <State>RESTRICTED</State>
          <ZIPCode>RESTRICTED</ZIPCode>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART XI, LINE 2D - OTHER ADJUSTMENTS:</FormAndLineReferenceDesc>
        <ExplanationTxt>FUNDRAISING DIRECT EXPENSES</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART XII, LINE 2D - OTHER ADJUSTMENTS:</FormAndLineReferenceDesc>
        <ExplanationTxt>FUNDRAISING DIRECT EXPENSES</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleD>
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      <InitialContractExceptionInd>0</InitialContractExceptionInd>
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        <TitleTxt>CEO</TitleTxt>
        <BaseCompensationFilingOrgAmt>349962</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>100000</BonusFilingOrganizationAmount>
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        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>0</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>35544</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>485506</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>RUIXIO LU</PersonNm>
        <TitleTxt>SENIOR SOFTWARE ENGINEER</TitleTxt>
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        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>1636</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>10801</DeferredCompensationFlngOrgAmt>
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        <NontaxableBenefitsFilingOrgAmt>35514</NontaxableBenefitsFilingOrgAmt>
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        <TotalCompensationFilingOrgAmt>319951</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>KARYN DIGIORGIO</PersonNm>
        <TitleTxt>COO</TitleTxt>
        <BaseCompensationFilingOrgAmt>249987</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>13039</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>6556</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>25593</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>295175</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>KATHRYN J WATSON-FEINER</PersonNm>
        <TitleTxt>DIRECTOR OF FINANCE</TitleTxt>
        <BaseCompensationFilingOrgAmt>269117</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>14232</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>8599</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>0</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>291948</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>TRACEY L HEATHER</PersonNm>
        <TitleTxt>DIRECTOR OF DEVELOPMENT</TitleTxt>
        <BaseCompensationFilingOrgAmt>205036</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>10980</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>8766</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>34622</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>259404</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>PAUL HENDERSON</PersonNm>
        <TitleTxt>SENIOR DIRECTOR OF COLLABO</TitleTxt>
        <BaseCompensationFilingOrgAmt>197400</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>0</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>11005</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>0</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>0</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>7269</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>0</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>34622</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>0</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>250296</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>0</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>PART I, LINE 3</FormAndLineReferenceDesc>
        <ExplanationTxt>BONUSES ARE APPROVED BY THE BOARD OF DIRECTORS.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleJ>
    <IRS990ScheduleO documentId="RetDoc1044400001">
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 11B</FormAndLineReferenceDesc>
        <ExplanationTxt>FORM 990 IS PREPARED BY AN INDEPENDENT CPA FIRM IN CONJUNCTION WITH THE ORGANIZATION'S DIRECTOR OF FINANCE. A DRAFT OF FORM 990 IS REVIEWED BY THE DIRECTOR OF FINANCE, AND CORRECTIONS/MODIFICATIONS ARE MADE BY THE OUTSIDE CPA. THE REVISED DRAFT IS THEN REVIEWED BY THE DIRECTOR OF FINANCE. ANY CONCERNS ARE RAISED WITH THE CPA FIRM AND A CONSENSUS IS ACHIEVED. BOARD MEMBERS ARE SENT A COPY OF THE TAX RETURN PRIOR TO FILING FOR THEIR REVIEW. THE RETURN IS THEN FINALIZED AND ELECTRONICALLY FILED WITH THE TAXING AUTHORITIES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 12C</FormAndLineReferenceDesc>
        <ExplanationTxt>THE CONFLICT OF INTEREST POLICY IS PRESENTED AND REVIEWED ANNUALLY. EACH BOARD MEMBER IS REQUIRED TO ACKNOWLEDGE IN WRITING THAT NO CONFLICT EXISTS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION B, LINE 15</FormAndLineReferenceDesc>
        <ExplanationTxt>COMPENSATION OF THE PRESIDENT OF THE ORGANIZATION WAS DETERMINED AND APPROVED BY VOTE OF THE BOARD OF DIRECTORS. PERSONNEL OF UCSF REVIEWED JOB REQUIREMENTS AGAINST TECHNICAL ABILITIES OF SUBCONTRACTORS AND DETERMINED WHETHER OR NOT THEY MATCHED. ALL SUBCONTRACTORS WERE ENGAGED AT BELOW-MARKET RATES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART VI, SECTION C, LINE 19</FormAndLineReferenceDesc>
        <ExplanationTxt>ALL GOVERNING DOCUMENTS, AUDITED FINANCIAL STATEMENTS AND FORM 990, RETURN OF ORGANIZATION EXEMPT FROM INCOME TAX, ARE PROVIDED UPON WRITTEN REQUEST OR THROUGH THE QUANTUM LEAP HEALTHCARE COLLABORATIVE WEBSITE, AS WELL AS TO ANYONE WHO REQUESTS THEM IN WRITING. THEY ARE ALSO AVAILABLE FOR INSPECTION AT THE QLHC OFFICE DURING NORMAL BUSINESS HOURS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>FORM 990, PART XI, LINE 9:</FormAndLineReferenceDesc>
        <ExplanationTxt>RETURNED UNSOLD ACTION ITEMS -36,097.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleO>
  </ReturnData>
</Return>
