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        <PersonNm>C Simmons</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>W Arden</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>A Roussel</PersonNm>
        <TitleTxt>Divisional Director</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>S Earnshaw</PersonNm>
        <TitleTxt>Divisional Director</TitleTxt>
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        <OtherCompensationAmt>49107</OtherCompensationAmt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>H Martin</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>E Sax</PersonNm>
        <TitleTxt>Treasurer</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>C Buchholtz</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>F Gilliam New 31821</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>C Cornwell</PersonNm>
        <TitleTxt>Vice President</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>A Helwig</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>T Piccione Separated 9420</PersonNm>
        <TitleTxt>Former Vice President</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>P Scott III</PersonNm>
        <TitleTxt>Chairman</TitleTxt>
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      <Form990PartVIISectionAGrp>
        <PersonNm>R Williams New 62521</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>H Pinnix-Ragland</PersonNm>
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      <Form990PartVIISectionAGrp>
        <PersonNm>J Moellering</PersonNm>
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        <PersonNm>C Shaffer</PersonNm>
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        <PersonNm>C Carter Separated 92220</PersonNm>
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        <PersonNm>T Darden</PersonNm>
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        <PersonNm>P Lange</PersonNm>
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        <PersonNm>W Mitchell</PersonNm>
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        <PersonNm>B Winn Separated 123120</PersonNm>
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        <PersonNm>M Powell New 31821</PersonNm>
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        <PersonNm>C Nye New 31821</PersonNm>
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          <StateAbbreviationCd>NY</StateAbbreviationCd>
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        <IRCSectionDesc>501(c)(3)</IRCSectionDesc>
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          <StateAbbreviationCd>CO</StateAbbreviationCd>
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        <IRCSectionDesc>501(c)(3)</IRCSectionDesc>
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          <StateAbbreviationCd>NC</StateAbbreviationCd>
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          <StateAbbreviationCd>NC</StateAbbreviationCd>
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          <StateAbbreviationCd>AL</StateAbbreviationCd>
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          <CityNm>Raleigh</CityNm>
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          <StateAbbreviationCd>NC</StateAbbreviationCd>
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          <StateAbbreviationCd>MA</StateAbbreviationCd>
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          <CityNm>Durham</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
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          <StateAbbreviationCd>CO</StateAbbreviationCd>
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          <CityNm>Waltham</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02451</ZIPCd>
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          <CityNm>Durham</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27713</ZIPCd>
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        <PurposeOfGrantTxt>General Support</PurposeOfGrantTxt>
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          <CityNm>New York</CityNm>
          <StateAbbreviationCd>NY</StateAbbreviationCd>
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          <CityNm>Des Moines</CityNm>
          <StateAbbreviationCd>IA</StateAbbreviationCd>
          <ZIPCd>50310</ZIPCd>
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          <CityNm>New York</CityNm>
          <StateAbbreviationCd>NY</StateAbbreviationCd>
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          <CityNm>Merrifield</CityNm>
          <StateAbbreviationCd>VA</StateAbbreviationCd>
          <ZIPCd>22116</ZIPCd>
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        <CashGrantAmt>15000</CashGrantAmt>
        <PurposeOfGrantTxt>General Support</PurposeOfGrantTxt>
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          <AddressLine1Txt>1430 S Wilmington Street</AddressLine1Txt>
          <CityNm>Raleigh</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27603</ZIPCd>
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          <CityNm>Chapel Hill</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27516</ZIPCd>
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          <CityNm>Raleigh</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27612</ZIPCd>
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        <CashGrantAmt>10000</CashGrantAmt>
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          <AddressLine1Txt>864 West Morgan Street</AddressLine1Txt>
          <CityNm>Raleigh</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27603</ZIPCd>
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          <CityNm>Twin Falls</CityNm>
          <StateAbbreviationCd>ID</StateAbbreviationCd>
          <ZIPCd>83301</ZIPCd>
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          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27713</ZIPCd>
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          <CityNm>Raleigh</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27617</ZIPCd>
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        <CashGrantAmt>6000</CashGrantAmt>
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          <CityNm>Chapel Hill</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
          <ZIPCd>27514</ZIPCd>
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          <CityNm>Washington</CityNm>
          <StateAbbreviationCd>DC</StateAbbreviationCd>
          <ZIPCd>20004</ZIPCd>
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          <CityNm>Washington</CityNm>
          <StateAbbreviationCd>DC</StateAbbreviationCd>
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          <CityNm>Morrisville</CityNm>
          <StateAbbreviationCd>NC</StateAbbreviationCd>
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          <StateAbbreviationCd>NC</StateAbbreviationCd>
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        <FormAndLineReferenceDesc>Part I, Line 1a</FormAndLineReferenceDesc>
        <ExplanationTxt>One highly compensated employee received tax gross up payments related to their international assignment in addition to payment for housing which was included in taxable income. Personal services for tax preparation was provided to one highly compensated employee and it was included in taxable income. Exclusively for its business purposes, RTI maintains memberships to two business clubs, where leaders in industry and business gather. No taxable income has been imputed to the senior executives who use these RTI club memberships exclusively for RTI business purposes.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Part I, Line 4b</FormAndLineReferenceDesc>
        <ExplanationTxt>The Institute implemented a long term incentive plan designed to reward executives to ensure the organization's finances are strong and to retain executives. This plan recognizes that the executives' total compensation is below market. Rather than increasing salaries, annual incentives or supplemental retirement benefits, the Board implemented a cash based retention plan which is dependent on the Institute's continued strong performance. Amounts paid and accrued during the calendar year 2020 are as follows: E. Holden $581,219, J. Gibson $303,935, M. Kaelin $248,076, T. Gabel $244,467, A. Mangel $240,786, G. Story $233,278, P. Weisenfeld $229,987, L. May $210,911, A. Helwig $9,360. These amounts include payments totaling $674,609 which were accrued and reported in prior years as deferred compensation.</ExplanationTxt>
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        <FormAndLineReferenceDesc>Part I, Line 7</FormAndLineReferenceDesc>
        <ExplanationTxt>RTI maintains variable compensation plans which are reviewed and approved annually by the Compensation Committee of the Board, as well as the full Board, to establish appropriate measurable targets and objectives along with incentive amounts. Actual performance under the plans is reviewed after the performance period and approved by the Compensation Committee and full Board as well. Amounts paid under these plans during the calendar year 2020 are as follows: E. Holden $350,764, J. Gibson $140,467, M. Kaelin $132,332, T. Gabel $128,745, A. Mangel $128,268, G. Story $117,105, L. May $111,767, P. Weisenfeld $107,493, C. Simmons $91,427, S. Earnshaw $76,303, A. Roussel $75,000, C. Hill $75,000, E. Sax $59,000, C. Cornwell $55,000, C. Buchholtz $55,000, and A. Helwig $30,000.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Part I, Line 8</FormAndLineReferenceDesc>
        <ExplanationTxt>RTI recruits its executive leadership from the national labor market, and this practice can introduce variability into each executive's initial compensation package. Accordingly, amounts were paid and accrued during the 2020 calendar year that emanated from RTI's offer of employment to certain executives and these items were included in the executive's employment agreement with RTI. Amounts paid were reported as taxable income and are included in the 2020 bonus or other compensation columns for each executive that received such payment. Any unpaid accruals are included in the deferred compensation column.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III, Line 4a</FormAndLineReferenceDesc>
        <ExplanationTxt>HEALTH RESEARCH is our largest single field of study, encompassing research that ranges from studies of the human genome and the development of new drug compounds to national surveys of health behaviors and the implementation of global health programs. Our activities in DRUG DISCOVERY AND DEVELOPMENT include working with pharmaceutical companies and government agencies to bring new medicines to market, and to ensure the safety and efficacy of those in the marketplace. As part of a comprehensive EDUCATION AND TRAINING RESEARCH program, our experts conduct rigorous studies used to assess and improve the quality of early development, education, and employment programs in the United States and many other countries. We also provide training solutions for forensic scientists and law enforcement. RTI is a leader in SURVEY RESEARCH and SURVEY STATISTICS. With a staff of highly skilled researchers using advanced data collection systems and techniques, we offer broad-based survey services for public and private sector studies. Our SURVEY RESEARCH SERVICES include study design, instrument development and evaluation, pretests and pilot studies, mail surveys, telephone surveys, face-to-face field surveys, Web surveys, records abstraction, collection of biological specimens, mixed-mode surveys, subject tracing, focus groups, and health registries. Our STATISTICS RESEARCH experts conduct complex statistical analyses to support wide ranging research programs in both laboratory and social sciences as well as ensure the quality, validity, and reliability of our research products and results by applying quality control and assurance procedures from sampling design through data collection and analysis. Our multidisciplinary ECONOMIC &amp; SOCIAL RESEARCH team includes experts in economics, demography, health, education, urban planning, and public financing. We provide independent, objective information and analyses that help to inform and improve public policy discourse and advance economic and social development decision making in technology, economics and policy, crime and justice, and food and nutrition policy. We provide ADVANCED TECHNOLOGY RESEARCH &amp; DEVELOPMENT services through the identification, development, application, and transfer of leading-edge technologies in areas including Materials Science; Electronics; Microfabrication; Information Technology; Innovation Advising; and Technology Economics &amp; Policy. Our ENERGY RESEARCHERS develop advanced energy technologies to address today's significant energy challenges, such as climate change, energy security, energy efficiency, sustainability, and water conservation. Our research supports national and worldwide goals of reliable, sustainable, economically viable, and secure energy supplies. We are a leading provider of ENVIRONMENTAL RESEARCH SERVICES for the U.S. Environmental Protection Agency and other government agencies. We conduct large-scale environmental management projects for both government and industry, helping them make critical policy and regulatory decisions. Our LABORATORY &amp; CHEMISTRY SERVICES support RTI research with state-of-the-art instrumentation, technologies, and processes. Our lab specifications and procedures emphasize quality control and excellence at every level of activity to meet the expectations and needs of our clients.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part III, Line 4b</FormAndLineReferenceDesc>
        <ExplanationTxt>INTERNATIONAL DEVELOPMENT Our experts in international development are dedicated to improving the human condition in developing countries. With more than 1,440 international development staff members based around the world, we deliver advisory and training services at the national, sub-national, and local government levels, providing institutional development through the transfer of analytical tools and methods. We often work in multidisciplinary teams that cut across traditional sector boundaries. Our clients include the United States Agency for International Development, Asian Development Bank, World Bank, Inter-American Development Bank, and several agencies of the United Nations, as well as foundations and other regional and international organizations. Our INTERNATIONAL DEVELOPMENT service areas include Governance &amp; Stabilization; International Education; International Environmental Services; Global Health; Information &amp; Communication Technology; and Monitoring &amp; Evaluation.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section A, line 2</FormAndLineReferenceDesc>
        <ExplanationTxt>T. Darden &amp; R. Ingram Business Relationship; T. Darden &amp; C. Shaffer Business Relationship; R. Ingram &amp; C. Shaffer Business Relationship; S. Kornbluth &amp; L. Carin Business Relationship; S. Kornbluth &amp; R. Williams Business Relationship; P. Lange &amp; F. Gilliam Business Relationship; H. Martin &amp; T. Magnuson Business Relationship; H. Martin &amp; W. Arden Business Relationship; H. Martin &amp; L. Carin Business Relationship; H. Martin &amp; H. Ragland Business Relationship; H. Martin &amp; F. Gilliam Business Relationship; C. Shaffer &amp; T. Magnuson Business Relationship</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section A, line 6</FormAndLineReferenceDesc>
        <ExplanationTxt>Research Triangle Institute is a non-profit corporation incorporated under the laws of the State of North Carolina. The Members of the corporation include the persons who at the time occupy the following positions: President, The University of North Carolina, Duke University: one member of the Board of Trustees of Duke University, appointed by the Chair of the Board of Trustees of Duke University, for one or more terms of three years; and one member of the Board of Governors of the University of North Carolina, appointed by the Chair of the Board of Governors of the University of North Carolina, for one or more terms of three years. The members shall elect the Governors, review and act on fundamental corporate transactions approved by the Governors, and take such other actions as may be required by law. No part of the earnings of the corporation shall insure to the benefit of any member or individual.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section A, line 7a</FormAndLineReferenceDesc>
        <ExplanationTxt>The members shall elect the Governors as described in the Bylaws of the Corporation.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section A, line 7b</FormAndLineReferenceDesc>
        <ExplanationTxt>The members shall review and act on fundamental corporate transactions approved by the Governors and take such other actions as may be required by law. Fundamental corporate transactions are described in the Articles of Incorporation.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 11b</FormAndLineReferenceDesc>
        <ExplanationTxt>The Form 990 with required schedules was provided to the full Board of Governors prior to filing via posting on RTI's hosted board communication solution, Director's Desk. In addition, RTI management reviewed the process and steps undertaken in completing the form with the Audit and Compensation Committees of the Board, including a review of the full Form 990 with the Audit committee prior to dissemination to the full Board.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 12c</FormAndLineReferenceDesc>
        <ExplanationTxt>Members of the Board of Governors, Officers and Key Employees are required to complete an annual conflict of interest disclosure in accordance with the organization's policies and procedures. Each disclosure is reviewed by the Audit Committee Chair, Chair of the Board of Governors, or the Chief Ethics Officer to determine whether a conflict of interest exists and if so, whether it appears to be significant and may warrant further review according to the standards and guidelines of the policy.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 15</FormAndLineReferenceDesc>
        <ExplanationTxt>Each year, Research Triangle Institute (the Institute) management seeks the review and approval of the Institute's Compensation Committee and Board of Governors (Board) to ensure that the total compensation packages for its Chief Executive Officer (CEO) and other senior executives listed below are reasonable. The CEO and other senior executives are not involved in the Compensation Committee and Board's decision regarding reasonableness of the executive compensation packages. The Compensation Committee and the Board use independent compensation surveys conducted by nationally recognized independent firms. The independent survey includes compensation paid by comparable institutions (taxable as well as non-taxable) for functionally comparable positions and in comparable positions and in comparable geographic labor markets. The Compensation Committee and Board also uses an independent executive compensation consulting firm to review the survey data and provide comments opining on the reasonableness of the compensation for the Institute's senior executives. In 2019, the study covered the following executive positions: E. Holden, President and CEO, J. Gibson, Chief Operating Officer, T. Gabel, Executive Vice President, Social Statistical and Environmental Services, A. Mangel, Executive Vice President, Health Solutions, G. Story, Chief Legal Counsel and Government Affairs, L. May, Executive Vice President &amp; Chief Human Resource Officer, M. Kaelin, Chief Financial Officer, P. Weisenfeld, Executive Vice President, International Development Group, T. Piccione, Executive Vice President and Chief Information Officer. Also included in the independent review were the following positions: C. Cornwell, Vice President and Corporate Controller and E. Sax, Senior Vice President and Treasurer.</ExplanationTxt>
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      <SupplementalInformationDetail>
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        <ExplanationTxt>The organization makes its governing documents, conflict of interest policy and financial statements available to the public upon request.</ExplanationTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, Line 16b</FormAndLineReferenceDesc>
        <ExplanationTxt>RTI and its staff belong to and participate in consortiums and associations that are consistent with RTI's mission to improve the human condition. These affiliations are neither in form nor substance a joint venture for federal income taxation. While RTI has not entered into a joint venture with a taxable entity, RTI has adopted a joint venture policy in order to evaluate its participation for federal income tax purposes. Additionally, certain federal contracts are awarded on a cost share basis whereby a cost share subcontractor reimburses RTI for a percentage of the total contract costs. Cost share arrangements exist primarily with unrelated taxable entities.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VII, Section A, Line 1b</FormAndLineReferenceDesc>
        <ExplanationTxt>RTI was established in 1958 by Duke University and the University of North Carolina System as the founding tenant of Research Triangle Park in North Carolina. It has grown into one of the world's leading independent nonprofit research organizations and is dedicated to conducting research and development that improves the human condition by turning knowledge into practice. Based on RTI's corporate governance structure, compensation of those Board Members employed by supported organizations (i.e. Duke and UNC System) is reported in column (E) and was obtained from the 990 information request questionnaire that was distributed to these listed persons and Duke University. These amounts were paid by either Duke Universiy or The University of North Carolina (UNC System). Given the supporting relationship with these universities, RTI is requested to report these amounts; however, RTI has no influence over this compensation.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part IX, line 11g</FormAndLineReferenceDesc>
        <ExplanationTxt>Subcontractors &amp; Consultants: Program service expenses 321,594,623. Management and general expenses 1,831,574. Fundraising expenses 0. Total expenses 323,426,197. Other Services: Program service expenses 79,418,934. Management and general expenses 13,995,683. Fundraising expenses 0. Total expenses 93,414,617. Passthroughs: Program service expenses 17,784,741. Management and general expenses 0. Fundraising expenses 0. Total expenses 17,784,741.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part XI, line 9:</FormAndLineReferenceDesc>
        <ExplanationTxt>Pension related changes 3,100,180. George Watts HIll Fund-Unrealized Gains (Permanently Restricted) -188,860. George Watts HIll Fund-Other Income (Temporarily Restricted) 92,635. Other Income/Expense Corporate Adjustments -6,774,730. Foreign Currency Translation 25,966.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleO>
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          <AddressLine1Txt>PO Box 12194</AddressLine1Txt>
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        <PrimaryActivitiesTxt>Health Economics and Outcome Research</PrimaryActivitiesTxt>
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          <AddressLine1Txt>PO Box 12194</AddressLine1Txt>
          <CityNm>Research Triangle Park</CityNm>
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