2023-09-08T11:45:22-05:00 2022-12-31 042571780 AAFCPAS INC 50 WASHINGTON STREET WESTBOROUGH MA 01581 990 2022-01-01 043462719 ALS THERAPY DEVELOPMENT FOUNDATION INC ALST 6174417200 480 ARSENAL STREET SUITE 201 WATERTOWN MA 02472 FERNANDO VIEIRA CEO/CSO 6174417200 2023-09-05 1 FERNANDO VIEIRA XXX-XX-XXXX 0 THOMAS F MULDOON CPA P01561688 5083669100 2023-09-05 2 AAL1 IAL1 2022 2023-04-26 12:10:37Z ALS THERAPY DEVELOPMENT INSTITUTE FERNANDO VIEIRA 480 ARSENAL STREET SUITE 201 WATERTOWN MA 02472 12385061 0 X WWW.ALS.NET X 1999 MA WE ARE COMMITTED TO CREATING AND LEADING A TRANSPARENT COLLABORATIVE RESEARCH PROCESS THAT INVOLVES ALS PATIENTS TODAY AND HONORS THOSE WHOSE JOURNEY WITH THIS DISEASE HAS ENDED. WE ARE GUIDED BY PASSION, LOVE AND THE SPIRIT OF ENTREPRENEURSHIP UPON WHICH WE WERE FOUNDED. 19 18 59 500 0 0 11401098 9817402 628036 636927 8195 66813 333322 843027 12370651 11364169 0 0 0 0 4112758 4486981 0 0 459735 4874728 5342558 8987486 9829539 3383165 1534630 19047011 21051525 2525249 5823044 16521762 15228481 OUR MISSION IS TO IDENTIFY VIABLE TARGETS FOR THERAPY DEVELOPMENT AND EXPEDITIOUSLY MANAGE THE CREATION OF THOSE TREATMENTS THAT WILL ARREST THE SUFFERING OF TODAY'S ALS PATIENTS. 0 0 8832734 740089 ALS TDI COMBINES THE PASSION AND DEDICATION OF A NONPROFIT ORGANIZATION WITH THE ENTREPRENEURIAL AND SCIENTIFIC SPIRIT OF A BIOTECHNOLOGY COMPANY. OUR LABORATORY IS THE LEADING DRUG DISCOVERY PROGRAM FOR ALS, AND IT BRIDGES A CRITICAL RESEARCH GAP. OUR IN-HOUSE EXPERTISE TRANSLATES RESEARCH INTO POTENTIAL DRUG CANDIDATES BY SCREENING DRUGS IN THE SOD1 MOUSE MODEL OF ALS. OUR SCIENTIFIC COLLABORATIONS ARE DESIGNED TO BRING THE MOST PROMISING LEADS CLOSER TO PATIENT USE. WE SHARE EMERGING KNOWLEDGE ON THE DISEASE WITH PATIENTS, PHYSICIANS, AND RESEARCHERS AS QUICKLY AND COMPREHENSIVELY AS POSSIBLE. EVERY DECISION IS MADE IN THE INTEREST OF FINDING EFFECTIVE TREATMENTS FOR PEOPLE LIVING WITH ALS. OUR UNIQUE APPROACH ACCELERATES DRUG DEVELOPMENT FOR ALS. 8832734 1 1 0 0 0 0 0 0 0 0 1 0 0 1 1 1 1 0 0 0 0 0 0 0 1 0 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 30 0 1 59 1 0 0 0 0 0 1 1 0 0 0 0 0 0 X 19 18 1 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 AL AK AZ AR CA CO CT DE FL GA HI ID IL IN IA KS KY LA ME MD MA MI MN MS MO MT NE NV NH NJ NM NY NC ND OH OK OR PA RI SC TN TX SD UT VT VA WA WV WY WI X X INSOURCE SERVICES INC 7812351490 148 LINDEN STREET WELLESLEY MA 02482 FERNANDO VIEIRA CEO / CSO 40.00 X X 315125 0 15687 ALAN GILL VP OF RESEARCH 40.00 X 170654 0 8280 MATVEY LUKASHEV VP OF TRANSLATION SCIENCES 40.00 X 160332 0 13251 CAROL HAMILTON VP OF DEVELOPMENT 40.00 X 148199 0 8280 KYLE DENTON DIRECTOR, CELL BIOLOGY 40.00 X 134069 0 20622 THEO HATZIPETROS DIRECTOR OF PHARMACOLOGY 40.00 X 130026 0 6711 AUGIE NIETO CHAIRMAN AND BOARD MEMBER 2.50 X X 0 0 0 STEVEN PERRIN PHD VICE CHAIR 2.50 X X 0 0 0 THEODORE REICH JD CPA TREASURER AND BOARD MEMBER 2.50 X X 0 0 0 LYNNE NIETO BOARD MEMBER 2.50 X 0 0 0 ALEXANDER CAPPELLO BOARD MEMBER 2.50 X 0 0 0 DR SPIROS JAMAS SCD BOARD MEMBER 2.50 X 0 0 0 JAMES ALLEN HEYWOOD BOARD MEMBER 2.50 X 0 0 0 JOHN B HEYWOOD PHD SCD BOARD MEMBER 2.50 X 0 0 0 ROB RODIN BOARD MEMBER 2.50 X 0 0 0 PAUL SALLABERRY BOARD MEMBER 2.50 X 0 0 0 ROBERT SEPUCHA BOARD MEMBER 2.50 X 0 0 0 JENNY DWYER BOARD MEMBER 2.50 X 0 0 0 MIKE SMITH BOARD MEMBER 2.50 X 0 0 0 JULIE SWAN BOARD MEMBER 2.50 X 0 0 0 KENT JACKSON BRANSFORD MD BOARD MEMBER 2.50 X 0 0 0 ANDREW NIBLOCK BOARD MEMBER 2.50 X 0 0 0 DR STANLEY H APPEL MD BOARD MEMBER 2.50 X 0 0 0 TOM ENGELLENNER BOARD MEMBER 2.50 X 0 0 0 1058405 0 72831 10 0 1 0 INSOURCE SERVICES INC PO BOX 427 NEWTON UPPER FALLS MA 02464 FINANCE, HR & IT 488389 LATHROP GAGE 2345 GRAND BLVD SUITE 2800 KANSAS CITY MO 64108 LEGAL 112260 2 4277656 739875 4799871 9817402 PHARMACEUTICAL CONTRACTS 541700 636927 636927 636927 66813 66813 1760757 4277656 1020892 739865 739865 CONTRACTED SERVICES 541900 103162 103162 103162 11364169 740089 0 806678 330812 264650 33081 33081 3354892 3020575 210998 123319 35071 30993 2655 1423 495469 434933 40352 20184 270737 241604 17818 11315 45707 45707 40526 40526 648317 535397 56897 56023 16941 1606 15335 103986 88171 5777 10038 593192 538803 11189 43200 1389977 1363872 9811 16294 79452 55375 3543 20534 11720 11720 227972 211720 10021 6231 100986 88312 6628 6046 TESTING AND LAB EXPENSE 1848719 1848719 PROGRAM SUPPLIES AND MA 81481 42377 17696 21408 BANK AND CREDIT CARD PR 75615 3190 72425 MISCELLANEOUS 32523 15311 16810 402 45444 38596 4371 2477 9829539 8832734 537070 459735 3608722 3467200 7350760 7748460 45000 389388 1049523 1053475 233017 174487 2863050 2670914 251537 192136 5845830 3231414 662622 775666 0 4019299 19047011 21051525 393423 532001 232684 94575 65565 739875 1093702 5196468 2525249 5823044 X 16521762 14928481 300000 16521762 15228481 19047011 21051525 1534630 -2827911 0 X X 0 1 X 1 0 X 12729824 11823260 8062216 10588016 9817402 53020718 12729824 11823260 8062216 10588016 9817402 53020718 2514515 50506203 34605 50014 17725 8195 66813 177352 396903 279636 90017 3794 103162 873512 54071582 3117093 0.93410 0.90630 X SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME: OTHER INCOME RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 0 62470 58278 4192 2800580 2612636 187944 192136 RIGHT-OF-USE ASSET - OPERATING 3601897 RIGHT-OF-USE ASSET - FINANCE 417402 4019299 OPERATING LEASE LIABILITY 4765986 FINANCE LEASE LIABILITY 430482 5196468 X 8541059 -2827911 4801 -2823110 11364169 0 11364169 9834340 4801 4801 9829539 0 9829539 PART X, LINE 2: ALS TDI ACCOUNTS FOR UNCERTAINTY IN INCOME TAXES IN ACCORDANCE WITH ASC TOPIC, INCOME TAXES. THIS STANDARD CLARIFIES THE ACCOUNTING FOR UNCERTAINTY IN TAX POSITIONS AND PRESCRIBES A RECOGNITION THRESHOLD AND MEASUREMENT ATTRIBUTE FOR THE FINANCIAL STATEMENTS REGARDING A TAX POSITION TAKEN OR EXPECTED TO BE TAKEN IN A TAX RETURN. ALS TDI HAS DETERMINED THAT THERE ARE NO UNCERTAIN TAX POSITIONS WHICH QUALIFY FOR EITHER RECOGNITION OR DISCLOSURE IN THEIR FINANCIAL STATEMENTS AT DECEMBER 31, 2022. THE INFORMATIONAL RETURNS OF ALS TDI ARE SUBJECT TO EXAMINATION BY THE FEDERAL AND STATE JURISDICTIONS AND GENERALLY REMAIN OPEN FOR THE MOST RECENT THREE YEARS. WHITE COAT AFFAIR 1021262 893006 128256 86992 50249 4190 34778 TRI-STAT TREK 607983 598583 9400 81211 26510 111745 303 4409168 2786067 1623101 267619 278476 7933 71189 6038413 4277656 1760757 435822 355235 12123 217712 1020892 739865 X X X X 0 0 0 0 0 0 0 0 0 FERNANDO VIEIRA CEO / CSO 315125 0 0 0 0 0 1000 0 14687 0 330812 0 0 0 ALAN GILL VP OF RESEARCH 170654 0 0 0 0 0 1000 0 7280 0 178934 0 0 0 MATVEY LUKASHEV VP OF TRANSLATION SCIENCES 160332 0 0 0 0 0 1000 0 12251 0 173583 0 0 0 CAROL HAMILTON VP OF DEVELOPMENT 148199 0 0 0 0 0 1000 0 7280 0 156479 0 0 0 KYLE DENTON DIRECTOR, CELL BIOLOGY 134069 0 0 0 0 0 1000 0 19622 0 154691 0 0 0 FORM 990, PART VI, SECTION A, LINE 2 JAMES HEYWOOD, BOARD MEMBER, IS THE SON OF JOHN HEYWOOD, MEMBER OF THE BOARD OF DIRECTORS. ADDITIONALLY, LYNNE NIETO AND KENT BRANSFORD, BOARD MEMBERS, ARE THE WIFE AND BROTHER-IN-LAW, RESPECTIVELY, OF AUGIE NIETO, BOARD MEMBER. FORM 990, PART VI, SECTION B, LINE 11B FORM 990 IS REVIEWED BY THE CHIEF FINANCIAL OFFICER AND THEN APPROVED BY THE BOARD OF DIRECTORS. FORM 990, PART VI, SECTION B, LINE 12C ALS TDI HAS A WRITTEN CONFLICT OF INEREST POLICY WHICH REQUIRES ANNUAL SIGNOFFS BY OFFICERS, DIRECTORS AND KEY EMPLOYEES. FORM 990, PART VI, SECTION B, LINE 15 THE PROCESS TO DETERMINE THE COMPENSATION OF THE PRESIDENT CONSISTS OF EVALUATING COMPARABLE DATA FOR FUNCTIONALLY SIMILAR POSITIONS AT SIMILAR ORGANIZATIONS, ALONG WITH THE REVIEW AND APPROVAL BY THE EXECUTIVE COMPENSATION COMMITTEE OF THE BOARD OF DIRECTORS WHICH IS COMPRISED OF INDEPENDENT MEMBERS. FORM 990, PART VI, SECTION B, LINE 15B: THE PROCESS TO ESTABLISH COMPENSATION OF OTHER OFFICERS AND KEY EMPLOYEES IS COMPLETED ON AN ANNUAL BASIS BY EVALUATING COMPARABLE DATA FOR FUNCTIONALLY SIMILAR POSITIONS AT SIMILAR ORGANIZATIONS, PRESENTING RECOMMENDATIONS TO THE EXECUTIVE COMPENSATION COMMITTEE OF THE BOARD OF DIRECTORS WHICH IS COMPRISED OF INDEPENDENT MEMBERS AND DOCUMENTING SUCH DISCUSSIONS IN THE BOARD MINUTES. FORM 990, PART VI, SECTION C, LINE 18 ALS TDI'S FORM 990 IS AVAILABLE FOR PUBLIC INSPECTION ON ALS TDI'S WEBSITE AND AT WWW.GUIDESTAR.COM. ALS TDI'S FORM 1023 IS AVAILABLE UPON REQUEST. FORM 990, PART VI, SECTION C, LINE 19 FINANCIAL STATEMENTS ARE MADE AVAILABLE ON ALS TDI'S WEBSITE AND ARE AVAILABLE BY MAIL UPON REQUEST. GOVERNING DOCUMENTS AND ALS TDI'S CONFLICT OF INTEREST POLICY ARE AVAILABLE UPON REQUEST. FORM 990, PART XII, LINE 2C: DURING 2022, THE ORGANIZATION DID NOT CHANGE THE WAY IN WHICH ITS COMMITTEE ASSUMES RESPONSIBILITY FOR OVERSIGHT OF THE AUDIT, ITS FINANCIAL STATEMENTS, AND SELECTION OF AN INDEPENDENT ACCOUNTANT.