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      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>Jeffrey Meyerhardt MD PhD</BusinessNameLine1Txt>
        </BusinessName>
        <TitleTxt>Trustee</TitleTxt>
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        <CompensationBasedOnRltdOrgsAmt>444194</CompensationBasedOnRltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>David P Ryan MD</BusinessNameLine1Txt>
        </BusinessName>
        <TitleTxt>Trustee</TitleTxt>
        <BaseCompensationFilingOrgAmt>0</BaseCompensationFilingOrgAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>Ravi I Thadhani MD MPH</BusinessNameLine1Txt>
        </BusinessName>
        <TitleTxt>Trustee</TitleTxt>
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        <CompensationBasedOnRltdOrgsAmt>814477</CompensationBasedOnRltdOrgsAmt>
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        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
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      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>Edward J Benz JR MD</BusinessNameLine1Txt>
        </BusinessName>
        <TitleTxt>Former Officer</TitleTxt>
        <BaseCompensationFilingOrgAmt>0</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>376204</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>0</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>1000</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>1786450</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>0</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>33925</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>0</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>17560</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>0</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>2215139</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>818568</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>Richard S Boskey ESQ</BusinessNameLine1Txt>
        </BusinessName>
        <TitleTxt>Former Officer</TitleTxt>
        <BaseCompensationFilingOrgAmt>0</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>610413</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>0</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>148600</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>40387</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>0</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>33925</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>0</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>17423</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>0</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>850748</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
      </RltdOrgOfficerTrstKeyEmplGrp>
      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>Laurie H Glimcher MD</BusinessNameLine1Txt>
        </BusinessName>
        <TitleTxt>Former Officer</TitleTxt>
        <BaseCompensationFilingOrgAmt>0</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>1280223</CompensationBasedOnRltdOrgsAmt>
        <BonusFilingOrganizationAmount>0</BonusFilingOrganizationAmount>
        <BonusRelatedOrganizationsAmt>212479</BonusRelatedOrganizationsAmt>
        <OtherCompensationFilingOrgAmt>0</OtherCompensationFilingOrgAmt>
        <OtherCompensationRltdOrgsAmt>2179953</OtherCompensationRltdOrgsAmt>
        <DeferredCompensationFlngOrgAmt>0</DeferredCompensationFlngOrgAmt>
        <DeferredCompRltdOrgsAmt>304525</DeferredCompRltdOrgsAmt>
        <NontaxableBenefitsFilingOrgAmt>0</NontaxableBenefitsFilingOrgAmt>
        <NontaxableBenefitsRltdOrgsAmt>16878</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>0</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>3994058</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>1191078</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>Sally Mason Boemer</BusinessNameLine1Txt>
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        <TitleTxt>Treasurer</TitleTxt>
        <BaseCompensationFilingOrgAmt>0</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>1039102</CompensationBasedOnRltdOrgsAmt>
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        <BonusRelatedOrganizationsAmt>405033</BonusRelatedOrganizationsAmt>
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        <OtherCompensationRltdOrgsAmt>75540</OtherCompensationRltdOrgsAmt>
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        <NontaxableBenefitsRltdOrgsAmt>31779</NontaxableBenefitsRltdOrgsAmt>
        <TotalCompensationFilingOrgAmt>0</TotalCompensationFilingOrgAmt>
        <TotalCompensationRltdOrgsAmt>1583354</TotalCompensationRltdOrgsAmt>
        <CompReportPrior990FilingOrgAmt>0</CompReportPrior990FilingOrgAmt>
        <CompReportPrior990RltdOrgsAmt>0</CompReportPrior990RltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <BusinessName>
          <BusinessNameLine1Txt>Hillary Mankin-Kufe ESQ</BusinessNameLine1Txt>
        </BusinessName>
        <TitleTxt>Clerk (as of 3/28/22)</TitleTxt>
        <BaseCompensationFilingOrgAmt>0</BaseCompensationFilingOrgAmt>
        <CompensationBasedOnRltdOrgsAmt>227311</CompensationBasedOnRltdOrgsAmt>
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        <OtherCompensationRltdOrgsAmt>4258</OtherCompensationRltdOrgsAmt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
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          <BusinessNameLine1Txt>John Ryan ESQ</BusinessNameLine1Txt>
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        <TitleTxt>Clerk (END 1/14/22)</TitleTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule J, Part I, Line 3 Arrangement used to establish the top management official's compensation</FormAndLineReferenceDesc>
        <ExplanationTxt>PROCESS FOR DETERMINING COMPENSATION OF PRESIDENT: FOR FY22, THE COMPENSATION COMMITTEE OF THE BOARD OF TRUSTEES OF DFCI REVIEWS THE PERFORMANCE OF THE PRESIDENT AND MAKES A RECOMMENDATION REGARDING COMPENSATION TO DFCI'S EXECUTIVE COMMITTEE, WHICH THEN APPROVES SUCH COMPENSATION.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule J, Part I, Line 4b Supplemental nonqualified retirement plan</FormAndLineReferenceDesc>
        <ExplanationTxt>THE FOLLOWING INDIVIDUALS PARTICIPATE IN 457(F) PLANS ESTABLISHED BY DFCI; TAXABLE AMOUNTS ARE INCLUDED IN REPORTABLE COMPENSATION IN SCHEDULE J, PART II, COLUMN (B)(III): LAURIE H. GLIMCHER, MD $2,162,958 EDWARD J. BENZ, JR., MD $1,779,950 BRUCE JOHNSON, MD $29,099 RICHARD S. BOSKEY, ESQ $28,155 RAMESH A. SHIVDASANI, MD $17,484</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Schedule J, Part II, Column (B)(iii) AND COLUMN C</FormAndLineReferenceDesc>
        <ExplanationTxt>THE DEFERRED COMPENSATION AWARDS/OTHER BENEFITS FIGURE MAY INCLUDE AWARDS OF DEFERRED COMPENSATION, THE VALUE OF OTHER EMPLOYEE TAXABLE BENEFITS IN WHICH THE EMPLOYEE PARTICIPATES, SUCH AS LIFE INSURANCES, DEFERRED COMPENSATION PLANS, TUITION BENEFIT PLANS, HOUSING ALLOWANCES, AND THE VALUE OF NON-TAXABLE EMPLOYEE BENEFIT PLANS SUCH AS PENSION, GROUP HEALTH, LIFE, AND DISABILITY WHICH THE EMPLOYER PROVIDES TO EMPLOYEES ON A NON-DISCRIMINATORY BASIS AS REQUIRED BY THE IRS. NONE OF THE OFFICERS OR EMPLOYEES RECEIVE EXPENSE ACCOUNTS OR ALLOWANCES WHICH CONSTITUTE TAXABLE COMPENSATION. THE CORPORATION HAS AN "ACCOUNTABLE PLAN" WHICH PAYS FOR OR REIMBURSES EXPENSES ONLY IF THEY ARE "ORDINARY, NECESSARY, AND REASONABLE" EXPENSES "INCURRED FOR A BONA FIDE BUSINESS PURPOSE." THE CORPORATION CARRIES LIABILITY INSURANCE THAT COVERS ITS TRUSTEES AND OFFICERS. THIS INSURANCE COVERAGE PROVIDES AN INCIDENTAL BENEFIT TO THE COVERED INDIVIDUALS.</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleJ>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 7a and Line 7B - POWER TO ELECT OR APPOINT GOVERNING BODY</FormAndLineReferenceDesc>
        <ExplanationTxt>THE MEMBERS HAVE THE AUTHORITY TO ELECT OR APPOINT THE GOVERNING BODY OF DF/MGBCC, INC. CERTAIN GOVERNANCE DECISIONS RELATING TO SIGNIFICANT TRANSACTIONS, AMENDMENTS TO THE GOVERNING DOCUMENTS OF THE CORPORATION AND THE DISSOLUTION OF THE CORPORATION ARE RESERVED TO THE MEMBERS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 6 Classes of members or stockholders</FormAndLineReferenceDesc>
        <ExplanationTxt>DANA-FARBER CANCER INSTITUTE, INC. ("DFCI") AND MASS GENERAL BRIGHAM, INC. ("MGB") ARE THE MEMBERS OF DANA-FARBER/MASS GENERAL BRIGHAM CANCER CARE, INC. ("DF/MGBCC, INC.")</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 11b Review of form 990 by governing body</FormAndLineReferenceDesc>
        <ExplanationTxt>THE DANA-FARBER CANCER INSTITUTE TAX DEPARTMENT PROVIDES ALL FINANCIAL ANALYSIS AND OTHER INFORMATION TO BE INCLUDED ON THE TAX RETURN TO ITS EXTERNAL TAX PREPARER, ERNST &amp; YOUNG LLP, WHICH PREPARES THE DRAFT RETURN. THE DRAFT RETURN IS REVIEWED BY THE TREASURER AND THE BOARD OF TRUSTEES. A FINAL VERSION OF THE FORM IS MADE AVAILABLE TO THE BOARD BEFORE FILING WITH THE IRS.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 12c Conflict of interest policy</FormAndLineReferenceDesc>
        <ExplanationTxt>DF/MGBCC, INC. HAS A WRITTEN CONFLICT OF INTEREST POLICY THAT IS CONSISTENT WITH THE IRS SAMPLE CONFLICT OF INTEREST POLICY. PER THE DF/MGBCC, INC. CONFLICT OF INTEREST POLICY, IN ORDER TO AVOID A CONFLICT OF INTEREST OR AN APPEARANCE OF A CONFLICT OF INTEREST A TRUSTEE SHOULD NOT PARTICIPATE IN A VOTE ON A TRANSACTION IN WHICH THE TRUSTEE OR FAMILY MEMBER HAS A FINANCIAL INTEREST AND SHOULD DISCLOSE ANY POTENTIAL CONFLICT BEFORE DF/MGBCC, INC. ACTS ON THE TRANSACTION. IF A DISCLOSURE WAS MADE, THE BOARD OF TRUSTEES WOULD INVESTIGATE ALTERNATIVES TO THE PROPOSED TRANSACTION AND DETERMINE WHETHER A MORE ADVANTAGEOUS TRANSACTION THAT WOULD NOT GIVE RISE TO A CONFLICT WOULD BE REASONABLY ATTAINABLE. IF SUCH A TRANSACTION IS NOT ATTAINABLE, A TRANSACTION WITH A TRUSTEE, A MEMBER OF HIS OR HER FAMILY, OR AN ENTITY WITH WHICH ONE OR MORE OF THEM HAS A MATERIAL INTEREST, MAY BE APPROVED BY THE MAJORITY VOTE OF THE DISINTERESTED TRUSTEES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 15a Process to establish compensation of top management official</FormAndLineReferenceDesc>
        <ExplanationTxt>FOR FY22, THE COMPENSATION COMMITTEE OF THE BOARD OF TRUSTEES OF DFCI REVIEWS THE PERFORMANCE OF THE PRESIDENT AND MAKES A RECOMMENDATION REGARDING COMPENSATION TO DFCI'S EXECUTIVE COMMITTEE, WHICH THEN APPROVES SUCH COMPENSATION.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Line 19 Required documents available to the public</FormAndLineReferenceDesc>
        <ExplanationTxt>GOVERNING DOCUMENTS: WE CURRENTLY PROVIDE THE GOVERNING DOCUMENTS UPON REQUEST. THE ARTICLES OF ORGANIZATION ARE ALSO AVAILABLE TO THE PUBLIC ON THE SECRETARY OF THE COMMONWEALTH'S WEBSITE. CONFLICT OF INTEREST POLICY: DF/MGBCC, INC.'S CONFLICT OF INTEREST POLICY IS AVAILABLE UPON REQUEST. FINANCIAL STATEMENTS: AUDITED FINANCIAL STATEMENTS ARE PROVIDED UPON REQUEST.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VII, Section A line 1a</FormAndLineReferenceDesc>
        <ExplanationTxt>THE INDIVIDUALS WHO HAVE COMPENSATION FROM RELATED ORGANIZATIONS IN COLUMN E SPEND THE REMAINDER OF THEIR FULL-TIME HOURS WORKING FOR DANA-FARBER CANCER INSTITUTE, INC. OR MASS GENERAL BRIGHAM, INC. AND ITS AFFILIATES.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part IX, Line 11g Other Fees</FormAndLineReferenceDesc>
        <ExplanationTxt>INST. SUPPORT - Total Expense: 97123248, Program Service Expense: 97123248, Management and General Expenses: 0, Fundraising Expenses: 0;</ExplanationTxt>
      </SupplementalInformationDetail>
    </IRS990ScheduleO>
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        <DisregardedEntityName>
          <BusinessNameLine1Txt>DANA-FARBER CANCER INSTITUTE INC</BusinessNameLine1Txt>
        </DisregardedEntityName>
        <USAddress>
          <AddressLine1Txt>450 BROOKLINE AVENUE BP418</AddressLine1Txt>
          <CityNm>BOSTON</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02215</ZIPCd>
        </USAddress>
        <EIN>042603040</EIN>
        <PrimaryActivitiesTxt>CANCER CARE</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>MA</LegalDomicileStateCd>
        <ExemptCodeSectionTxt>501(c)(3)</ExemptCodeSectionTxt>
        <PublicCharityStatusTxt>7</PublicCharityStatusTxt>
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          <BusinessNameLine1Txt>THE GENERAL HOSPITAL CORPORATION</BusinessNameLine1Txt>
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        <USAddress>
          <AddressLine1Txt>55 FRUIT STREET</AddressLine1Txt>
          <CityNm>BOSTON</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02215</ZIPCd>
        </USAddress>
        <EIN>042697983</EIN>
        <PrimaryActivitiesTxt>HOSPITAL</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>MA</LegalDomicileStateCd>
        <ExemptCodeSectionTxt>501(c)(3)</ExemptCodeSectionTxt>
        <PublicCharityStatusTxt>3</PublicCharityStatusTxt>
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        <ControlledOrganizationInd>false</ControlledOrganizationInd>
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      <IdRelatedTaxExemptOrgGrp>
        <DisregardedEntityName>
          <BusinessNameLine1Txt>THE BRIGHAM &amp; WOMEN'S HOSPITAL</BusinessNameLine1Txt>
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          <AddressLine1Txt>75 FRANCIS STREET</AddressLine1Txt>
          <CityNm>BOSTON</CityNm>
          <StateAbbreviationCd>MA</StateAbbreviationCd>
          <ZIPCd>02215</ZIPCd>
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        <EIN>042312909</EIN>
        <PrimaryActivitiesTxt>HOSPITAL</PrimaryActivitiesTxt>
        <LegalDomicileStateCd>MA</LegalDomicileStateCd>
        <ExemptCodeSectionTxt>501(c)(3)</ExemptCodeSectionTxt>
        <PublicCharityStatusTxt>3</PublicCharityStatusTxt>
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          <BusinessNameLine1Txt>NA</BusinessNameLine1Txt>
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      <ReceiptOfIntAnntsRntsRyltsInd>false</ReceiptOfIntAnntsRntsRyltsInd>
      <GiftGrntOrCapContriToOthOrgInd>false</GiftGrntOrCapContriToOthOrgInd>
      <GiftGrntCapContriFromOthOrgInd>false</GiftGrntCapContriFromOthOrgInd>
      <LoansOrGuaranteesToOtherOrgInd>false</LoansOrGuaranteesToOtherOrgInd>
      <LoansOrGuaranteesFromOthOrgInd>false</LoansOrGuaranteesFromOthOrgInd>
      <DivRelatedOrganizationInd>false</DivRelatedOrganizationInd>
      <AssetSaleToOtherOrgInd>false</AssetSaleToOtherOrgInd>
      <AssetPurchaseFromOtherOrgInd>false</AssetPurchaseFromOtherOrgInd>
      <AssetExchangeInd>false</AssetExchangeInd>
      <RentalOfFacilitiesToOthOrgInd>false</RentalOfFacilitiesToOthOrgInd>
      <RentalOfFcltsFromOthOrgInd>false</RentalOfFcltsFromOthOrgInd>
      <PerformOfServicesForOthOrgInd>false</PerformOfServicesForOthOrgInd>
      <PerformOfServicesByOtherOrgInd>true</PerformOfServicesByOtherOrgInd>
      <SharingOfFacilitiesInd>false</SharingOfFacilitiesInd>
      <PaidEmployeesSharingInd>false</PaidEmployeesSharingInd>
      <ReimbursementPaidToOtherOrgInd>false</ReimbursementPaidToOtherOrgInd>
      <ReimbursementPaidByOtherOrgInd>false</ReimbursementPaidByOtherOrgInd>
      <TransferToOtherOrgInd>false</TransferToOtherOrgInd>
      <TransferFromOtherOrgInd>false</TransferFromOtherOrgInd>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>DANA-FARBER CANCER INSTITUTE INC</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>M</TransactionTypeTxt>
        <InvolvedAmt>50143679</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>COST</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>THE GENERAL HOSPITAL CORPORATION</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>M</TransactionTypeTxt>
        <InvolvedAmt>36663077</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>COST</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
      <TransactionsRelatedOrgGrp>
        <OtherOrganizationName>
          <BusinessNameLine1Txt>THE BRIGHAM AND WOMEN'S HOSPITAL</BusinessNameLine1Txt>
        </OtherOrganizationName>
        <TransactionTypeTxt>M</TransactionTypeTxt>
        <InvolvedAmt>5623322</InvolvedAmt>
        <MethodOfAmountDeterminationTxt>COST</MethodOfAmountDeterminationTxt>
      </TransactionsRelatedOrgGrp>
    </IRS990ScheduleR>
  </ReturnData>
</Return>
