﻿<?xml version="1.0" encoding="utf-8"?>
<Return xmlns="http://www.irs.gov/efile" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.irs.gov/efile" returnVersion="2024v5.1">
  <ReturnHeader binaryAttachmentCnt="0">
    <ReturnTs>2025-04-16T09:04:44-05:00</ReturnTs>
    <TaxPeriodEndDt>2024-12-31</TaxPeriodEndDt>
    <PreparerFirmGrp>
      <PreparerFirmEIN>161131146</PreparerFirmEIN>
      <PreparerFirmName>
        <BusinessNameLine1Txt>Bonadio &amp; Co LLP</BusinessNameLine1Txt>
      </PreparerFirmName>
      <PreparerUSAddress>
        <AddressLine1Txt>2711 Centerville Road Suite 100</AddressLine1Txt>
        <CityNm>Wilmington</CityNm>
        <StateAbbreviationCd>DE</StateAbbreviationCd>
        <ZIPCd>19808</ZIPCd>
      </PreparerUSAddress>
    </PreparerFirmGrp>
    <ReturnTypeCd>990PF</ReturnTypeCd>
    <TaxPeriodBeginDt>2024-01-01</TaxPeriodBeginDt>
    <Filer>
      <EIN>510349682</EIN>
      <BusinessName>
        <BusinessNameLine1Txt>AstraZeneca Foundation</BusinessNameLine1Txt>
        <BusinessNameLine2Txt>(fka AstraZeneca Healthcare Foundation)</BusinessNameLine2Txt>
      </BusinessName>
      <BusinessNameControlTxt>ASTR</BusinessNameControlTxt>
      <PhoneNum>3028863000</PhoneNum>
      <USAddress>
        <AddressLine1Txt>1800 Concord Pike</AddressLine1Txt>
        <CityNm>Wilmington</CityNm>
        <StateAbbreviationCd>DE</StateAbbreviationCd>
        <ZIPCd>198502910</ZIPCd>
      </USAddress>
    </Filer>
    <BusinessOfficerGrp>
      <PersonNm>Theresa Rogler</PersonNm>
      <PersonTitleTxt>Assistant Treasurer</PersonTitleTxt>
      <PhoneNum>3028863000</PhoneNum>
      <SignatureDt>2025-04-10</SignatureDt>
      <DiscussWithPaidPreparerInd>1</DiscussWithPaidPreparerInd>
    </BusinessOfficerGrp>
    <IRSResponsiblePrtyInfoCurrInd>1</IRSResponsiblePrtyInfoCurrInd>
    <PreparerPersonGrp>
      <PreparerPersonNm>Peter S Kennedy CPA</PreparerPersonNm>
      <PTIN>P00571422</PTIN>
      <PhoneNum>3026566632</PhoneNum>
      <PreparationDt>2025-04-03</PreparationDt>
    </PreparerPersonGrp>
    <TaxYr>2024</TaxYr>
    <BuildTS>2025-03-06 01:10:19Z</BuildTS>
  </ReturnHeader>
  <ReturnData documentCnt="11">
    <IRS990PF documentId="RetDoc1235000001" referenceDocumentId="RetDoc1175200001">
      <NameChangeInd>X</NameChangeInd>
      <Organization501c3ExemptPFInd>X</Organization501c3ExemptPFInd>
      <FMVAssetsEOYAmt>40542918</FMVAssetsEOYAmt>
      <MethodOfAccountingAccrualInd>X</MethodOfAccountingAccrualInd>
      <AnalysisOfRevenueAndExpenses>
        <ContriRcvdRevAndExpnssAmt>200</ContriRcvdRevAndExpnssAmt>
        <ScheduleBNotRequiredInd>X</ScheduleBNotRequiredInd>
        <DividendsRevAndExpnssAmt>398806</DividendsRevAndExpnssAmt>
        <DividendsNetInvstIncmAmt>398806</DividendsNetInvstIncmAmt>
        <NetGainSaleAstRevAndExpnssAmt>0</NetGainSaleAstRevAndExpnssAmt>
        <GrossSalesPriceAmt>4260000</GrossSalesPriceAmt>
        <CapGainNetIncmNetInvstIncmAmt>0</CapGainNetIncmNetInvstIncmAmt>
        <OtherIncomeRevAndExpnssAmt referenceDocumentId="RetDoc2001500001">1548140</OtherIncomeRevAndExpnssAmt>
        <OtherIncomeNetInvstIncmAmt>0</OtherIncomeNetInvstIncmAmt>
        <TotalRevAndExpnssAmt>1947146</TotalRevAndExpnssAmt>
        <TotalNetInvstIncmAmt>398806</TotalNetInvstIncmAmt>
        <CompOfcrDirTrstRevAndExpnssAmt>0</CompOfcrDirTrstRevAndExpnssAmt>
        <CompOfcrDirTrstNetInvstIncmAmt>0</CompOfcrDirTrstNetInvstIncmAmt>
        <CompOfcrDirTrstDsbrsChrtblAmt>0</CompOfcrDirTrstDsbrsChrtblAmt>
        <LegalFeesRevAndExpnssAmt referenceDocumentId="RetDoc2002100001">19461</LegalFeesRevAndExpnssAmt>
        <LegalFeesNetInvstIncmAmt>0</LegalFeesNetInvstIncmAmt>
        <LegalFeesDsbrsChrtblAmt>23067</LegalFeesDsbrsChrtblAmt>
        <AccountingFeesRevAndExpnssAmt referenceDocumentId="RetDoc2002200001">26544</AccountingFeesRevAndExpnssAmt>
        <AccountingFeesNetInvstIncmAmt>0</AccountingFeesNetInvstIncmAmt>
        <AccountingFeesChrtblPrpsAmt>26448</AccountingFeesChrtblPrpsAmt>
        <OtherProfFeesRevAndExpnssAmt referenceDocumentId="RetDoc2002300001">555536</OtherProfFeesRevAndExpnssAmt>
        <OtherProfFeesNetInvstIncmAmt>34754</OtherProfFeesNetInvstIncmAmt>
        <OtherProfFeesDsbrsChrtblAmt>629953</OtherProfFeesDsbrsChrtblAmt>
        <TaxesRevAndExpnssAmt referenceDocumentId="RetDoc2002500001">5060</TaxesRevAndExpnssAmt>
        <TaxesNetInvstIncmAmt>0</TaxesNetInvstIncmAmt>
        <TaxesDsbrsChrtblAmt>0</TaxesDsbrsChrtblAmt>
        <TravConfMeetingRevAndExpnssAmt>1993</TravConfMeetingRevAndExpnssAmt>
        <TravConfMeetingNetInvstIncmAmt>0</TravConfMeetingNetInvstIncmAmt>
        <TravConfMeetingDsbrsChrtblAmt>5660</TravConfMeetingDsbrsChrtblAmt>
        <OtherExpensesRevAndExpnssAmt referenceDocumentId="RetDoc2003200001">92182</OtherExpensesRevAndExpnssAmt>
        <OtherExpensesNetInvstIncmAmt>0</OtherExpensesNetInvstIncmAmt>
        <OtherExpensesDsbrsChrtblAmt>99287</OtherExpensesDsbrsChrtblAmt>
        <TotOprExpensesRevAndExpnssAmt>700776</TotOprExpensesRevAndExpnssAmt>
        <TotOprExpensesNetInvstIncmAmt>34754</TotOprExpensesNetInvstIncmAmt>
        <TotOprExpensesDsbrsChrtblAmt>784415</TotOprExpensesDsbrsChrtblAmt>
        <ContriPaidRevAndExpnssAmt>1495139</ContriPaidRevAndExpnssAmt>
        <ContriPaidDsbrsChrtblAmt>1495139</ContriPaidDsbrsChrtblAmt>
        <TotalExpensesRevAndExpnssAmt>2195915</TotalExpensesRevAndExpnssAmt>
        <TotalExpensesNetInvstIncmAmt>34754</TotalExpensesNetInvstIncmAmt>
        <TotalExpensesDsbrsChrtblAmt>2279554</TotalExpensesDsbrsChrtblAmt>
        <ExcessRevenueOverExpensesAmt>-248769</ExcessRevenueOverExpensesAmt>
        <NetInvestmentIncomeAmt>364052</NetInvestmentIncomeAmt>
      </AnalysisOfRevenueAndExpenses>
      <Form990PFBalanceSheetsGrp>
        <CashBOYAmt>54496</CashBOYAmt>
        <CashEOYAmt>28942</CashEOYAmt>
        <CashEOYFMVAmt>28942</CashEOYFMVAmt>
        <GrantsReceivableBOYAmt>34025066</GrantsReceivableBOYAmt>
        <GrantsReceivableEOYAmt>31573206</GrantsReceivableEOYAmt>
        <GrantsReceivableEOYFMVAmt>31573206</GrantsReceivableEOYFMVAmt>
        <OtherInvestmentsBOYAmt>6650839</OtherInvestmentsBOYAmt>
        <OtherInvestmentsEOYAmt referenceDocumentId="RetDoc2018100001">8937830</OtherInvestmentsEOYAmt>
        <OtherInvestmentsEOYFMVAmt>8937830</OtherInvestmentsEOYFMVAmt>
        <OtherAssetsBOYAmt referenceDocumentId="RetDoc2046600001">1800</OtherAssetsBOYAmt>
        <OtherAssetsEOYAmt referenceDocumentId="RetDoc2046600001">2940</OtherAssetsEOYAmt>
        <OtherAssetsEOYFMVAmt referenceDocumentId="RetDoc2046600001">2940</OtherAssetsEOYFMVAmt>
        <TotalAssetsBOYAmt>40732201</TotalAssetsBOYAmt>
        <TotalAssetsEOYAmt>40542918</TotalAssetsEOYAmt>
        <TotalAssetsEOYFMVAmt>40542918</TotalAssetsEOYFMVAmt>
        <AccountsPayableBOYAmt>119465</AccountsPayableBOYAmt>
        <AccountsPayableEOYAmt>30766</AccountsPayableEOYAmt>
        <TotalLiabilitiesBOYAmt>119465</TotalLiabilitiesBOYAmt>
        <TotalLiabilitiesEOYAmt>30766</TotalLiabilitiesEOYAmt>
        <OrganizationFollowsFASB117Ind>X</OrganizationFollowsFASB117Ind>
        <NoDonorRstrNetAssestsBOYAmt>19380251</NoDonorRstrNetAssestsBOYAmt>
        <NoDonorRstrNetAssestsEOYAmt>18106811</NoDonorRstrNetAssestsEOYAmt>
        <DonorRstrNetAssetsBOYAmt>21232485</DonorRstrNetAssetsBOYAmt>
        <DonorRstrNetAssetsEOYAmt>22405341</DonorRstrNetAssetsEOYAmt>
        <TotNetAstOrFundBalancesBOYAmt>40612736</TotNetAstOrFundBalancesBOYAmt>
        <TotNetAstOrFundBalancesEOYAmt>40512152</TotNetAstOrFundBalancesEOYAmt>
        <TotalLiabilitiesNetAstBOYAmt>40732201</TotalLiabilitiesNetAstBOYAmt>
        <TotalLiabilitiesNetAstEOYAmt>40542918</TotalLiabilitiesNetAstEOYAmt>
      </Form990PFBalanceSheetsGrp>
      <ChgInNetAssetsFundBalancesGrp>
        <TotNetAstOrFundBalancesBOYAmt>40612736</TotNetAstOrFundBalancesBOYAmt>
        <ExcessRevenueOverExpensesAmt>-248769</ExcessRevenueOverExpensesAmt>
        <OtherIncreasesAmt referenceDocumentId="RetDoc2049700001">148185</OtherIncreasesAmt>
        <SubtotalAmt>40512152</SubtotalAmt>
        <OtherDecreasesAmt>0</OtherDecreasesAmt>
        <TotNetAstOrFundBalancesEOYAmt>40512152</TotNetAstOrFundBalancesEOYAmt>
      </ChgInNetAssetsFundBalancesGrp>
      <CapGainsLossTxInvstIncmDetail>
        <CapGainsLossTxInvstIncmGrp>
          <PropertyDesc>Money Market Sales</PropertyDesc>
          <HowAcquiredCd>P</HowAcquiredCd>
          <AcquiredDt>2024-01-01</AcquiredDt>
          <SoldDt>2024-12-31</SoldDt>
          <GrossSalesPriceAmt>4260000</GrossSalesPriceAmt>
          <CostOrOtherBasisAmt>4260000</CostOrOtherBasisAmt>
          <GainOrLossAmt>0</GainOrLossAmt>
          <GainsMinusExcessOrLossesAmt>0</GainsMinusExcessOrLossesAmt>
        </CapGainsLossTxInvstIncmGrp>
        <CapitalGainNetIncomeAmt>0</CapitalGainNetIncomeAmt>
      </CapGainsLossTxInvstIncmDetail>
      <ExciseTaxBasedOnInvstIncmGrp>
        <InvestmentIncomeExciseTaxAmt>5060</InvestmentIncomeExciseTaxAmt>
        <TaxUnderSection511Amt>0</TaxUnderSection511Amt>
        <SubtotalAmt>5060</SubtotalAmt>
        <SubtitleATaxAmt>0</SubtitleATaxAmt>
        <TaxBasedOnInvestmentIncomeAmt>5060</TaxBasedOnInvestmentIncomeAmt>
        <EstimatedPlusOvpmtIncmTxAmt>8000</EstimatedPlusOvpmtIncmTxAmt>
        <ExemptFrgnOrgTaxWthldAtSrceAmt>0</ExemptFrgnOrgTaxWthldAtSrceAmt>
        <ExtsnRequestIncomeTaxPaidAmt>0</ExtsnRequestIncomeTaxPaidAmt>
        <BackupWithholdingWithheldAmt>0</BackupWithholdingWithheldAmt>
        <TotalPaymentsAndCreditsAmt>8000</TotalPaymentsAndCreditsAmt>
        <EsPenaltyAmt>0</EsPenaltyAmt>
        <OverpaymentAmt>2940</OverpaymentAmt>
        <AppliedToESTaxAmt>2940</AppliedToESTaxAmt>
        <RefundAmt>0</RefundAmt>
      </ExciseTaxBasedOnInvstIncmGrp>
      <StatementsRegardingActyGrp>
        <LegislativePoliticalActyInd>0</LegislativePoliticalActyInd>
        <MoreThan100SpentInd>0</MoreThan100SpentInd>
        <Form1120POLFiledInd>0</Form1120POLFiledInd>
        <Section4955OrganizationTaxAmt>0</Section4955OrganizationTaxAmt>
        <Section4955ManagersTaxAmt>0</Section4955ManagersTaxAmt>
        <TaxReimbursedAmt>0</TaxReimbursedAmt>
        <ActivitiesNotPreviouslyRptInd>0</ActivitiesNotPreviouslyRptInd>
        <ChangesToArticlesOrBylawsInd>1</ChangesToArticlesOrBylawsInd>
        <UnrelatedBusIncmOverLimitInd>0</UnrelatedBusIncmOverLimitInd>
        <OrganizationDissolvedEtcInd>0</OrganizationDissolvedEtcInd>
        <Section508eRqrSatisfiedInd>1</Section508eRqrSatisfiedInd>
        <AtLeast5000InAssetsInd>1</AtLeast5000InAssetsInd>
        <OrgReportOrRegisterStateCd>DE</OrgReportOrRegisterStateCd>
        <Form990PFFiledWithAttyGenInd>1</Form990PFFiledWithAttyGenInd>
        <PrivateOperatingFoundationInd>0</PrivateOperatingFoundationInd>
        <NewSubstantialContributorsInd>0</NewSubstantialContributorsInd>
        <OwnControlledEntityInd>0</OwnControlledEntityInd>
        <DonorAdvisedFundInd>0</DonorAdvisedFundInd>
        <ComplyWithPublicInspRqrInd>1</ComplyWithPublicInspRqrInd>
        <WebsiteAddressTxt>See Part XV</WebsiteAddressTxt>
        <PersonsWithBooksName>
          <BusinessNameLine1Txt>AstraZeneca Foundation</BusinessNameLine1Txt>
        </PersonsWithBooksName>
        <PhoneNum>3028863000</PhoneNum>
        <LocationOfBooksUSAddress>
          <AddressLine1Txt>1800 Concord Pike</AddressLine1Txt>
          <CityNm>Wilmington</CityNm>
          <StateAbbreviationCd>DE</StateAbbreviationCd>
          <ZIPCd>198505437</ZIPCd>
        </LocationOfBooksUSAddress>
        <ForeignAccountsQuestionInd>0</ForeignAccountsQuestionInd>
      </StatementsRegardingActyGrp>
      <StatementsRegardingActy4720Grp>
        <SaleOrExchDisqualifiedPrsnInd>0</SaleOrExchDisqualifiedPrsnInd>
        <BrrwOrLendDisqualifiedPrsnInd>0</BrrwOrLendDisqualifiedPrsnInd>
        <FurnGoodsDisqualifiedPrsnInd>1</FurnGoodsDisqualifiedPrsnInd>
        <PayCompDisqualifiedPrsnInd>0</PayCompDisqualifiedPrsnInd>
        <TransferAstDisqualifiedPrsnInd>0</TransferAstDisqualifiedPrsnInd>
        <PaymentToGovernmentOfficialInd>0</PaymentToGovernmentOfficialInd>
        <ActsFailToQlfyAsExceptionsInd>0</ActsFailToQlfyAsExceptionsInd>
        <UncorrectedPriorActsInd>0</UncorrectedPriorActsInd>
        <UndistributedIncomePYInd>0</UndistributedIncomePYInd>
        <BusinessHoldingsInd>0</BusinessHoldingsInd>
        <JeopardyInvestmentsInd>0</JeopardyInvestmentsInd>
        <UncorrectedPYJeopardyInvstInd>0</UncorrectedPYJeopardyInvstInd>
        <InfluenceLegislationInd>0</InfluenceLegislationInd>
        <InfluenceElectionInd>0</InfluenceElectionInd>
        <GrantsToIndividualsInd>0</GrantsToIndividualsInd>
        <GrantsToOrganizationsInd>0</GrantsToOrganizationsInd>
        <NoncharitablePurposeInd>0</NoncharitablePurposeInd>
        <RcvFndsToPayPrsnlBnftCntrctInd>0</RcvFndsToPayPrsnlBnftCntrctInd>
        <PayPremiumsPrsnlBnftCntrctInd>0</PayPremiumsPrsnlBnftCntrctInd>
        <ProhibitedTaxShelterTransInd>0</ProhibitedTaxShelterTransInd>
        <SubjToTaxRmnrtnExPrchtPymtInd>0</SubjToTaxRmnrtnExPrchtPymtInd>
      </StatementsRegardingActy4720Grp>
      <OfficerDirTrstKeyEmplInfoGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>JAMES W BLASETTO MD MPH FACC</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>CHAIRMAN (UNTIL 12/24)</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>3.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>MOHIT MANRAO</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>PRESIDENT (FROM 1/24)</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>MARIAM KOOHDARY</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>SECRETARY</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>DAVID E WHITE</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>TREASURER</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>THERESA ROGLER</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>ASSISTANT TREASURER</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>KEITH BURNS</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>ASSISTANT TREASURER</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>KEVIN DURNING</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>ASSISTANT TREASURER</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>RACHELE BERRIA MD PHD</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>TRUSTEE (UNTIL 11/24)</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>MATTHEW DIGGONS</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>TRUSTEE</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>BARRY MANN MD FACS</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>TRUSTEE</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>L KRISTIN NEWBY MD MHS</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>TRUSTEE</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>GAYLE PORTER PSYD</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>TRUSTEE</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>MIKA SOVAK MD PHD</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>TRUSTEE</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>2.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <OfficerDirTrstKeyEmplGrp>
          <PersonNm>BRIDGET THERRIAULT</PersonNm>
          <USAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </USAddress>
          <TitleTxt>EXECUTIVE DIRECTOR</TitleTxt>
          <AverageHrsPerWkDevotedToPosRt>12.00</AverageHrsPerWkDevotedToPosRt>
          <CompensationAmt>0</CompensationAmt>
          <EmployeeBenefitProgramAmt>0</EmployeeBenefitProgramAmt>
          <ExpenseAccountOtherAllwncAmt>0</ExpenseAccountOtherAllwncAmt>
        </OfficerDirTrstKeyEmplGrp>
        <CompOfHghstPdEmplOrNONETxt>NONE</CompOfHghstPdEmplOrNONETxt>
        <OtherEmployeePaidOver50kCnt>0</OtherEmployeePaidOver50kCnt>
        <CompensationOfHghstPdCntrctGrp>
          <BusinessName>
            <BusinessNameLine1Txt>KELLY SERVICES INC</BusinessNameLine1Txt>
          </BusinessName>
          <USAddress>
            <AddressLine1Txt>PO BOX 820405</AddressLine1Txt>
            <CityNm>PHILADELPHIA</CityNm>
            <StateAbbreviationCd>PA</StateAbbreviationCd>
            <ZIPCd>19182</ZIPCd>
          </USAddress>
          <ServiceTypeTxt>STAFFING</ServiceTypeTxt>
          <CompensationAmt>342563</CompensationAmt>
        </CompensationOfHghstPdCntrctGrp>
        <CompensationOfHghstPdCntrctGrp>
          <BusinessName>
            <BusinessNameLine1Txt>NORC at University of Chicago</BusinessNameLine1Txt>
          </BusinessName>
          <USAddress>
            <AddressLine1Txt>55 E Monroe St 30th Floor</AddressLine1Txt>
            <CityNm>Chicago</CityNm>
            <StateAbbreviationCd>IL</StateAbbreviationCd>
            <ZIPCd>60603</ZIPCd>
          </USAddress>
          <ServiceTypeTxt>Evaluation Services</ServiceTypeTxt>
          <CompensationAmt>254090</CompensationAmt>
        </CompensationOfHghstPdCntrctGrp>
        <CompensationOfHghstPdCntrctGrp>
          <BusinessName>
            <BusinessNameLine1Txt>HUNTSWORTH HOLDING INC DBA EVOKE KYNE</BusinessNameLine1Txt>
          </BusinessName>
          <USAddress>
            <AddressLine1Txt>300 VESEY ST 10TH FLOOR</AddressLine1Txt>
            <CityNm>NEW YORK</CityNm>
            <StateAbbreviationCd>NY</StateAbbreviationCd>
            <ZIPCd>10282</ZIPCd>
          </USAddress>
          <ServiceTypeTxt>CONSULTANT</ServiceTypeTxt>
          <CompensationAmt>80155</CompensationAmt>
        </CompensationOfHghstPdCntrctGrp>
        <ContractorPaidOver50kCnt>0</ContractorPaidOver50kCnt>
      </OfficerDirTrstKeyEmplInfoGrp>
      <SummaryOfDirectChrtblActyGrp>
        <Description1Txt>Program Reporting &amp; Evaluation:In 2024, the AstraZeneca Foundation, its evaluation partners and its Creating Health Access for Next Generation (CHANGE) grant awardees created an evaluation framework that centers community voices and assesses improvements in healthcare access. As part of the framework, awardees submit impact reports and in return, receive evaluations from our evaluation partners that assess their progress toward goals and may include recommendations to address challenges. Awardees have regular access to Foundation staff and evaluation partners for assistance. By year-end, all six CHANGE awardees met or exceeded objectives overall on their evaluations and improved access to healthcare such as through expanding service offerings, addressing patient barriers, providing preventative care and screenings, integrating care coordination services and helping patients obtain health insurance and increase health literacy.</Description1Txt>
        <Expenses1Amt>263212</Expenses1Amt>
        <Description2Txt>Community Advisory Board:As part of the AstraZeneca Foundation's Creating Health Access for Next Generation Equity (CHANGE) program, the Foundation and its evaluation partners virtually host monthly Community Advisory Board meetings to bring grant awardees and partners together for meaningful dialogue, shared learning and capacity building to help organizations maximize their impact. During this past year, these collaborative sessions focused on training and technical assistance to support grant awardee needs in reporting and evaluation and communications. Additionally, a learning forum brought together CHANGE awardees to foster connections and share lessons learned through presentations, interactive activities and group discussions.</Description2Txt>
        <Expenses2Amt>11866</Expenses2Amt>
        <Description3Txt>Awareness Building:The AstraZeneca Foundation amplifies the work of grant awardees and the importance of community health commitments through communications like social media, its Annual Report, e-mails to its distribution list of 2,000+ individuals, videos and blogs. In 2024, the Foundation supported six longstanding grant awardees in sharing their impact through videography. To help CHANGE grant awardees build capacity, the Foundation developed and provided a communications toolkit, which offered press release and social media templates to share their award notice. The Foundation also participated in an AstraZeneca Health Expo with its CHANGE grant awardees to raise awareness for their work. Lastly, the Foundation submitted an abstract to the American Public Health Association Annual Meeting to share its Mentorship Program learnings and toolkit with other philanthropic and nonprofit organizations.</Description3Txt>
        <Expenses3Amt>298899</Expenses3Amt>
        <Description4Txt>Grant Selection Process:The AstraZeneca Foundation's Grant Review Committee conducted a grant review to evaluate second-year Creating Health Access for Next Generation Equity (CHANGE) grant applications for organizations offering innovative, community-engaged approaches to improve access to quality healthcare. Each application was reviewed to ensure adherence to requirements, appropriate plans in place and a clearly defined budget. All grant applications were recommended by the Foundation Grant Review Committee for approval by the Board.</Description4Txt>
        <Expenses4Amt>69191</Expenses4Amt>
      </SummaryOfDirectChrtblActyGrp>
      <SumOfProgramRelatedInvstGrp>
        <TotalAmt>0</TotalAmt>
      </SumOfProgramRelatedInvstGrp>
      <MinimumInvestmentReturnGrp>
        <AverageMonthlyFMVOfSecAmt>8656102</AverageMonthlyFMVOfSecAmt>
        <AverageMonthlyCashBalancesAmt>75618</AverageMonthlyCashBalancesAmt>
        <FMVAllOtherNoncharitableAstAmt>0</FMVAllOtherNoncharitableAstAmt>
        <TotalFMVOfUnusedAssetsAmt>8731720</TotalFMVOfUnusedAssetsAmt>
        <ReductionClaimedAmt>0</ReductionClaimedAmt>
        <AcquisitionIndebtednessAmt>0</AcquisitionIndebtednessAmt>
        <AdjustedTotalFMVOfUnusedAstAmt>8731720</AdjustedTotalFMVOfUnusedAstAmt>
        <CashDeemedCharitableAmt>130976</CashDeemedCharitableAmt>
        <NetVlNoncharitableAssetsAmt>8600744</NetVlNoncharitableAssetsAmt>
        <MinimumInvestmentReturnAmt>430037</MinimumInvestmentReturnAmt>
      </MinimumInvestmentReturnGrp>
      <DistributableAmountGrp>
        <MinimumInvestmentReturnAmt>430037</MinimumInvestmentReturnAmt>
        <TaxBasedOnInvestmentIncomeAmt>5060</TaxBasedOnInvestmentIncomeAmt>
        <TotalTaxAmt>5060</TotalTaxAmt>
        <DistributableBeforeAdjAmt>424977</DistributableBeforeAdjAmt>
        <RecoveriesQualfiedDistriAmt>0</RecoveriesQualfiedDistriAmt>
        <DistributableBeforeDedAmt>424977</DistributableBeforeDedAmt>
        <DeductionFromDistributableAmt>0</DeductionFromDistributableAmt>
        <DistributableAsAdjustedAmt>424977</DistributableAsAdjustedAmt>
      </DistributableAmountGrp>
      <PFQualifyingDistributionsGrp>
        <ExpensesAndContributionsAmt>2279554</ExpensesAndContributionsAmt>
        <ProgramRelatedInvstTotalAmt>0</ProgramRelatedInvstTotalAmt>
        <QualifyingDistributionsAmt>2279554</QualifyingDistributionsAmt>
      </PFQualifyingDistributionsGrp>
      <UndistributedIncomeGrp>
        <DistributableAsAdjustedAmt>424977</DistributableAsAdjustedAmt>
        <UndistributedIncomePYAmt>0</UndistributedIncomePYAmt>
        <TotalForPriorYearsAmt>0</TotalForPriorYearsAmt>
        <ExcessDistributionCyovYr5Amt>1419199</ExcessDistributionCyovYr5Amt>
        <ExcessDistributionCyovYr4Amt>1587960</ExcessDistributionCyovYr4Amt>
        <ExcessDistributionCyovYr3Amt>1436769</ExcessDistributionCyovYr3Amt>
        <ExcessDistributionCyovYr2Amt>1265691</ExcessDistributionCyovYr2Amt>
        <ExcessDistributionCyovYr1Amt>2940276</ExcessDistributionCyovYr1Amt>
        <TotalExcessDistributionCyovAmt>8649895</TotalExcessDistributionCyovAmt>
        <QualifyingDistributionsAmt>2279554</QualifyingDistributionsAmt>
        <AppliedToYear1Amt>0</AppliedToYear1Amt>
        <AppliedToPriorYearsAmt>0</AppliedToPriorYearsAmt>
        <TreatedAsDistriFromCorpusAmt>0</TreatedAsDistriFromCorpusAmt>
        <AppliedToCurrentYearAmt>424977</AppliedToCurrentYearAmt>
        <RemainingDistriFromCorpusAmt>1854577</RemainingDistriFromCorpusAmt>
        <ExcessDistriCyovAppCYCorpusAmt>0</ExcessDistriCyovAppCYCorpusAmt>
        <ExcessDistributionCyovAppCYAmt>0</ExcessDistributionCyovAppCYAmt>
        <TotalCorpusAmt>10504472</TotalCorpusAmt>
        <PriorYearUndistributedIncmAmt>0</PriorYearUndistributedIncmAmt>
        <PriorYearDeficiencyOrTaxAmt>0</PriorYearDeficiencyOrTaxAmt>
        <Taxable1Amt>0</Taxable1Amt>
        <Taxable2Amt>0</Taxable2Amt>
        <UndistributedIncomeCYAmt>0</UndistributedIncomeCYAmt>
        <CorpusDistri170b1EOr4942g3Amt>0</CorpusDistri170b1EOr4942g3Amt>
        <ExcessDistriCyovFromYr5Amt>1419199</ExcessDistriCyovFromYr5Amt>
        <ExcessDistriCyovToNextYrAmt>9085273</ExcessDistriCyovToNextYrAmt>
        <ExcessFromYear4Amt>1587960</ExcessFromYear4Amt>
        <ExcessFromYear3Amt>1436769</ExcessFromYear3Amt>
        <ExcessFromYear2Amt>1265691</ExcessFromYear2Amt>
        <ExcessFromYear1Amt>2940276</ExcessFromYear1Amt>
        <ExcessFromCurrentYearAmt>1854577</ExcessFromCurrentYearAmt>
      </UndistributedIncomeGrp>
      <SupplementaryInformationGrp>
        <ApplicationSubmissionInfoGrp>
          <RecipientPersonNm>Submit via website</RecipientPersonNm>
          <RecipientUSAddress>
            <AddressLine1Txt>N/A</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>19850</ZIPCd>
          </RecipientUSAddress>
          <RecipientPhoneNum>3028863000</RecipientPhoneNum>
          <FormAndInfoAndMaterialsTxt>Applications are only accepted on the Foundation's website; www.astrazeneca-us.com/sustainability/healthcare-foundation.html</FormAndInfoAndMaterialsTxt>
          <SubmissionDeadlinesTxt>See statement 15</SubmissionDeadlinesTxt>
          <RestrictionsOnAwardsTxt>See statement 16</RestrictionsOnAwardsTxt>
        </ApplicationSubmissionInfoGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>AIDS Resource Alliance Inc</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>500 West Third Street</AddressLine1Txt>
            <CityNm>Williamsport</CityNm>
            <StateAbbreviationCd>PA</StateAbbreviationCd>
            <ZIPCd>17701</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>None</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>509(a)(1)</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Operational support - Creating Health Access for Next Generation Equity Program</GrantOrContributionPurposeTxt>
          <Amt>249997</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>Community Volunteers in Medicine</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>300 B Lawrence Drive</AddressLine1Txt>
            <CityNm>West Chester</CityNm>
            <StateAbbreviationCd>PA</StateAbbreviationCd>
            <ZIPCd>193809823</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>None</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>509(a)(1)</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Operational support - Creating Health Access for Next Generation Equity Program</GrantOrContributionPurposeTxt>
          <Amt>250000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>Health Care for the Homeless Inc</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>421 Fallsway</AddressLine1Txt>
            <CityNm>Baltimore</CityNm>
            <StateAbbreviationCd>MD</StateAbbreviationCd>
            <ZIPCd>21202</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>None</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>509(a)(1)</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Operational support - Creating Health Access for Next Generation Equity Program</GrantOrContributionPurposeTxt>
          <Amt>250000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientPersonNm>Individuals</RecipientPersonNm>
          <RecipientUSAddress>
            <AddressLine1Txt>C/O AZF PO Box 15437</AddressLine1Txt>
            <CityNm>Wilmington</CityNm>
            <StateAbbreviationCd>DE</StateAbbreviationCd>
            <ZIPCd>198505437</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>None</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>N/A</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Employee Disaster Relief Program</GrantOrContributionPurposeTxt>
          <Amt>33287</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>LCH Health and Community Services</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>731 West Cypress Street</AddressLine1Txt>
            <CityNm>Kennett Square</CityNm>
            <StateAbbreviationCd>PA</StateAbbreviationCd>
            <ZIPCd>19348</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>None</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>509(a)(1)</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Operational support - Creating Health Access for Next Generation Equity Program</GrantOrContributionPurposeTxt>
          <Amt>250000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>Mary's Center for Maternal and Child Care Inc</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>2333 Ontario Road NW</AddressLine1Txt>
            <CityNm>Washington</CityNm>
            <StateAbbreviationCd>DC</StateAbbreviationCd>
            <ZIPCd>200092627</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>None</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>509(a)(1)</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Operational support - Creating Health Access for Next Generation Equity Program</GrantOrContributionPurposeTxt>
          <Amt>211855</Amt>
        </GrantOrContributionPdDurYrGrp>
        <GrantOrContributionPdDurYrGrp>
          <RecipientBusinessName>
            <BusinessNameLine1Txt>SOME Inc</BusinessNameLine1Txt>
          </RecipientBusinessName>
          <RecipientUSAddress>
            <AddressLine1Txt>71 O Street NW</AddressLine1Txt>
            <CityNm>Washington</CityNm>
            <StateAbbreviationCd>DC</StateAbbreviationCd>
            <ZIPCd>20001</ZIPCd>
          </RecipientUSAddress>
          <RecipientRelationshipTxt>None</RecipientRelationshipTxt>
          <RecipientFoundationStatusTxt>509(a)(1)</RecipientFoundationStatusTxt>
          <GrantOrContributionPurposeTxt>Operational support - Creating Health Access for Next Generation Equity Program</GrantOrContributionPurposeTxt>
          <Amt>250000</Amt>
        </GrantOrContributionPdDurYrGrp>
        <TotalGrantOrContriPdDurYrAmt>1495139</TotalGrantOrContriPdDurYrAmt>
        <TotalGrantOrContriApprvFutAmt>0</TotalGrantOrContriApprvFutAmt>
      </SupplementaryInformationGrp>
      <AnalysisIncomeProducingActyGrp>
        <DividendsAndInterestFromSecDtl>
          <ExclusionCd>14</ExclusionCd>
          <ExclusionAmt>398806</ExclusionAmt>
        </DividendsAndInterestFromSecDtl>
        <OtherRevenueDescribedGrp>
          <Desc>Change in Pledge Discount</Desc>
          <BusinessCd>900099</BusinessCd>
          <RelatedOrExemptFunctionIncmAmt>1548140</RelatedOrExemptFunctionIncmAmt>
        </OtherRevenueDescribedGrp>
        <SubtotalsIncmProducingActyGrp>
          <UnrelatedBusinessTaxblIncmAmt>0</UnrelatedBusinessTaxblIncmAmt>
          <ExclusionAmt>398806</ExclusionAmt>
          <RelatedOrExemptFunctionIncmAmt>1548140</RelatedOrExemptFunctionIncmAmt>
        </SubtotalsIncmProducingActyGrp>
        <TotalIncomeProducingActyAmt>1946946</TotalIncomeProducingActyAmt>
      </AnalysisIncomeProducingActyGrp>
      <RlnOfActyToAccomOfExmptPrpsGrp>
        <RlnOfActyToAccomOfExmptPrpsGrp>
          <LineNumberTxt>11a</LineNumberTxt>
          <RelationshipStatementTxt>Amortization of discount on pledges receivable.</RelationshipStatementTxt>
        </RlnOfActyToAccomOfExmptPrpsGrp>
      </RlnOfActyToAccomOfExmptPrpsGrp>
      <TrnsfrTransRlnNonchrtblEOGrp>
        <TrnsfrOfCashToNonchrtblEOInd>0</TrnsfrOfCashToNonchrtblEOInd>
        <TrnsfrOtherAssetNonchrtblEOInd>0</TrnsfrOtherAssetNonchrtblEOInd>
        <SalesOrExchangesOfAssetsInd>0</SalesOrExchangesOfAssetsInd>
        <PurchaseOfAssetsNonchrtblEOInd>0</PurchaseOfAssetsNonchrtblEOInd>
        <RentalOfFacilitiesOthAssetsInd>0</RentalOfFacilitiesOthAssetsInd>
        <ReimbursementArrangementsInd>0</ReimbursementArrangementsInd>
        <LoansOrLoanGuaranteesInd>0</LoansOrLoanGuaranteesInd>
        <PerformanceOfServicesEtcInd>0</PerformanceOfServicesEtcInd>
        <SharingOfFacilitiesEtcInd>0</SharingOfFacilitiesEtcInd>
        <RelationshipsNonchrtblEOInd>0</RelationshipsNonchrtblEOInd>
      </TrnsfrTransRlnNonchrtblEOGrp>
    </IRS990PF>
    <AccountingFeesSchedule documentId="RetDoc2002200001">
      <AccountingFeesDetail>
        <CategoryTxt>ACCOUNTING FEES</CategoryTxt>
        <Amt>26544</Amt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>26448</DisbursementsCharitablePrpsAmt>
      </AccountingFeesDetail>
    </AccountingFeesSchedule>
    <GeneralExplanationAttachment documentId="RetDoc1175200001">
      <GeneralExplanationGrp>
        <IdentifierTxt>Creating Health Access for Next Generation Equity (CHANGE)</IdentifierTxt>
        <FormAndLineReferenceDesc>Part XIV, Line 2c</FormAndLineReferenceDesc>
        <MediumExplanationTxt>2024 Creating Health Access for Next Generation Equity (CHANGE) Grant Criteria:The AstraZeneca Foundation (Foundation) is committed to ensuring that everyone in the US has a fair and just opportunity to attain their highest level of health. The Foundation works to accomplish this by supporting nonprofit organizations with initiatives that address social determinants of health, or the conditions in which people are born, grow, live, work and age that impact health. As an important determinant of health outcomes, a key priority for the Foundation is improving access to timely and quality healthcare services. The Foundation recognizes that access to quality healthcare can be challenging due to barriers such as a lack of health insurance, transportation, employment and general socioeconomic status, among other factors. Accordingly, the AstraZeneca Foundation has established the Creating Health Access for Next Generation Equity (CHANGE) program. The CHANGE program awards Foundation grants to U.S.-based, nonprofit 501(c)(3) organizations or similar nonprofit organizations working in innovative, collaborative ways at the community level to improve access to quality healthcare. Our aim is for funded organizations to maximize the benefit to community members and community-based organizations and to work toward continuing their services beyond potential AstraZeneca Foundation funding. The intent of the 2024 grants is to provide continued funding for general operating support to organizations that received CHANGE grants in 2023 to continue to enhance access to quality healthcare.Organizational Criteria o Invited organizations need to maintain their status as a U.S.-based, nonprofit organization with a 501(c) designation or a public school, government entity or municipal institution that is eligible to accept tax-deductible, charitable contributions. Organizations that are a 501(c)(3) and also have an IRS designation as a 509(a)(3) are ineligible for funding. o After submitting the application, organizations cannot make substantive changes to their tax status. Once selected for a grant award, organizations cannot reassign, transfer or credit their grant to another entity, including any related entity, without prior written approval by the Foundation. Any changes in an organization's tax status after submitting the application or being selected for a grant award must be reported immediately and may impact the organization's eligibility to receive the grant. o The organization must continue to be based in the United States or its territories and serve communities in at least one of the following locations: Delaware, Maryland, Pennsylvania or Washington DC. Funding Criteria o The Foundation will fund requests between $200,000 and $250,000 for the second year, which may be renewed on an annual basis for up to one additional year. There is no guarantee of funding. o To be considered for continued funding, organizations must meet or exceed objectives overall in their 2023 Mid-Year Evaluation, as assessed by the Foundation's evaluation partners. Organizations not meeting or partially meeting objectives overall will be considered on a case-by-case basis by the Board of Trustees. o Any budget expenses allocated for healthcare provider compensation may support a portion of or up to the full annual salary of the healthcare provider but cannot be in addition to the healthcare provider's annual salary for the grant timeframe paid for by the applying organization. o While indirect costs and fringe benefits are not capped, grant requests should demonstrate that most funding will directly benefit community members and community-based organizations. Priority Communities o Organizations must continue to demonstrate a commitment to improving equitable access to quality healthcare. o Organizations that provide services in areas of low-income and/or remote/rural areas are expected to continue to do so. Focus Areas/Services o Organizations must continue to provide services tailored to the needs of their communities to help improve access to quality healthcare while considering the social determinants of health that impact community members. This may include but is not limited to: o Providing access to care services (e.g., screenings, wellness and prevention services) and coordination of care (e.g., case managers, health coaches, promotores) o Mitigating barriers that impact access to care services (e.g., transportation, affordability, physical accessibility, translation services, plain language materials) o Organizations are expected to continue to: o Offer innovative, community-engaged approaches to improving access to quality healthcare o Include collaboration with other community-based organizations in their approach o Create a new partnership and/or coalition or expand existing partnerships with other institutions to breakdown pre-existing silos and maximize benefit to the community through collaboration o Engage with their local communities/populations served to help guide decisions around services and accelerate local change o Conduct community-based outreach o Demonstrate robust plans to sustain their access to quality healthcare efforts (via fundraisers, grants, partnerships, reimbursable services etc.) o Organizations that include a focus on promoting screenings, early detection, treatment and/or continuity of care for cardiovascular, renal, respiratory or immunologic diseases and/or cancers are expected to continue to do so. o Organizations are encouraged to measure their overall impact on community health and to show potential to replicate their approach (e.g., sharing their approach with other communities and organizations). Exclusions o The Foundation does NOT fund applications that focus exclusively on the following: o Capital investments and unsolicited capital campaigns o Medical education and/or training (i.e., training necessary to obtain a degree or license) for healthcare professionals that is more than incidental and that is the primary focus of the grant's activities o Research or clinical trials o Healthcare provider salaries o Faith-based programs that are NOT open to the community-at-large o The Foundation does NOT support: o Initiatives outside the United States or its territories o Individuals o For-profit organizations o Endowments o Journals or advertising o Political causes, lobbying, fraternal or social organizations o Religious organizations whose activities are not open to the general public o Nonprofit organizations that discriminate on the basis of age, race, ethnicity, religion, national origin, gender, sexual orientation, marital status, military service, veteran status or disability Grant Application o Applying organizations will need to: o Provide 1) a copy of their current IRS 990 form or documents that confirm eligibility to receive charitable donations and 2) audited financials for the past fiscal year. (If audited financials are not available, unaudited financial statements may be submitted). o Identify a goal for the number of individuals to be reached through their access to quality healthcare efforts. o Identify key short-term goals of their efforts to improve access to quality healthcare during the grant year with a clear design for amplification of outcomes during the final year. Grant Execution o Grant awardees will be required to submit regular reports and other requirements to the Foundation according to deadlines and processes set forth in the Letter of Agreement. o Written approval from the Foundation is required from grant awardees prior to making a major change in objectives, budget or scope. Some examples include but are not limited to service location, target audience and goals. o Grant awardees (1-2 individuals per organization) must be available to participate in a Community Advisory Board, including up to monthly virtual meetings (with some potential in-person opportunities) with fellow grant awardees, Foundation staff and its evaluation partners to 1) collaborate on long-term goals and a plan for measuring improvements in access to quality healthcare and 2) participate in capacity-building activities such as webinars, learning forum(s) and consultations based on identified needs and provide peer support to other grant awardees. Note: Criteria for assessing applications is subject to change and may be updated by the AstraZeneca Foundation from year to year. Application cycles are planned on a year-by-year basis.</MediumExplanationTxt>
      </GeneralExplanationGrp>
      <GeneralExplanationGrp>
        <FormAndLineReferenceDesc>Part XIV, Line 2d</FormAndLineReferenceDesc>
        <MediumExplanationTxt>The AstraZeneca Foundation's mission is to advance health equity and foster community wellbeing. Through its signature program, Creating Health Access for Next Generation Equity (CHANGE), the Foundation provides grants to US-based nonprofit organizations working to improve access to quality healthcare in their communities. As part of their efforts, organizations focus on promoting screenings, early diagnosis, treatment and/or continuity of care for cardiovascular, renal, respiratory or immunologic diseases and/or cancers as well as expanding partnerships with the intent of breaking down institutional silos and maximizing benefit to the community through collaboration. CHANGE is more than a grantmaking platform; it is a philanthropic collaborative by which the Foundation brings funded organizations together for meaningful dialogue, capacity-building and shared learning and implementation.Since 2023, funded organizations have collectively reached more than 29,800 individuals with direct services, events and programming and have improved healthcare access through addressing barriers to care, integrating care coordination, expanding service offerings, providing preventative care and screenings, providing support for obtaining health insurance and increasing health literacy.In the second half of 2024, six current awardees serving communities in Delaware, Maryland, Pennsylvania and Washington, D.C., received second year CHANGE grants, totaling $1.46M, to continue their work to ensure access to healthcare for all. The CHANGE grant cycle will run through October of 2025 with the opportunity for up to one final year of additional funding upon meeting objectives. For more information, visit: https://www.astrazeneca-us.com/sustainability/healthcare-foundation/change.html.</MediumExplanationTxt>
      </GeneralExplanationGrp>
    </GeneralExplanationAttachment>
    <InvestmentsOtherSchedule2 documentId="RetDoc2018100001">
      <InvestmentsOtherGrp>
        <CategoryOrItemTxt>J.P. Morgan Prime MM Fund</CategoryOrItemTxt>
        <ListedAtCostOrFMVCd>FMV</ListedAtCostOrFMVCd>
        <BookValueAmt>4726638</BookValueAmt>
        <EOYFMVAmt>4726638</EOYFMVAmt>
      </InvestmentsOtherGrp>
      <InvestmentsOtherGrp>
        <CategoryOrItemTxt>Vanguard 500 Prime</CategoryOrItemTxt>
        <ListedAtCostOrFMVCd>FMV</ListedAtCostOrFMVCd>
        <BookValueAmt>2151312</BookValueAmt>
        <EOYFMVAmt>2151312</EOYFMVAmt>
      </InvestmentsOtherGrp>
      <InvestmentsOtherGrp>
        <CategoryOrItemTxt>Vanguard ST Bond Fund</CategoryOrItemTxt>
        <ListedAtCostOrFMVCd>FMV</ListedAtCostOrFMVCd>
        <BookValueAmt>2059880</BookValueAmt>
        <EOYFMVAmt>2059880</EOYFMVAmt>
      </InvestmentsOtherGrp>
    </InvestmentsOtherSchedule2>
    <LegalFeesSchedule documentId="RetDoc2002100001">
      <LegalFeesGrp>
        <CategoryTxt>LEGAL FEES</CategoryTxt>
        <LegalFeesAmt>19461</LegalFeesAmt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>23067</DisbursementsCharitablePrpsAmt>
      </LegalFeesGrp>
    </LegalFeesSchedule>
    <OtherAssetsSchedule documentId="RetDoc2046600001">
      <OtherAssetsScheduleGrp>
        <Desc>Prepaid Excise Tax</Desc>
        <BOYBookValueAmt>1800</BOYBookValueAmt>
        <EOYBookValueAmt>2940</EOYBookValueAmt>
        <EOYFMVAmt>2940</EOYFMVAmt>
      </OtherAssetsScheduleGrp>
    </OtherAssetsSchedule>
    <OtherExpensesSchedule documentId="RetDoc2003200001">
      <OtherExpensesScheduleGrp>
        <Desc>COMMUNICATION AND PUBLICATIONS</Desc>
        <RevenueAndExpensesPerBooksAmt>89745</RevenueAndExpensesPerBooksAmt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>96850</DisbursementsCharitablePrpsAmt>
      </OtherExpensesScheduleGrp>
      <OtherExpensesScheduleGrp>
        <Desc>INSURANCE</Desc>
        <RevenueAndExpensesPerBooksAmt>950</RevenueAndExpensesPerBooksAmt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>950</DisbursementsCharitablePrpsAmt>
      </OtherExpensesScheduleGrp>
      <OtherExpensesScheduleGrp>
        <Desc>PROFESSIONAL DEVELOPMENT AND MEMBERSHIPS</Desc>
        <RevenueAndExpensesPerBooksAmt>1487</RevenueAndExpensesPerBooksAmt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>1487</DisbursementsCharitablePrpsAmt>
      </OtherExpensesScheduleGrp>
    </OtherExpensesSchedule>
    <OtherIncomeSchedule2 documentId="RetDoc2001500001">
      <OtherIncomeDetail>
        <Desc>Change in Pledge Discount</Desc>
        <RevenueAndExpensesPerBooksAmt>1548140</RevenueAndExpensesPerBooksAmt>
        <AdjustedNetIncomeAmt>1548140</AdjustedNetIncomeAmt>
      </OtherIncomeDetail>
    </OtherIncomeSchedule2>
    <OtherIncreasesSchedule documentId="RetDoc2049700001">
      <OtherIncreasesDetail>
        <Desc>Unrealized Gain on Investments</Desc>
        <Amt>148185</Amt>
      </OtherIncreasesDetail>
    </OtherIncreasesSchedule>
    <OtherProfessionalFeesSchedule documentId="RetDoc2002300001">
      <OtherProfessionalFeesDetail>
        <CategoryTxt>CONTRACTOR EXPENSES</CategoryTxt>
        <Amt>347536</Amt>
        <NetInvestmentIncomeAmt>34754</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>342563</DisbursementsCharitablePrpsAmt>
      </OtherProfessionalFeesDetail>
      <OtherProfessionalFeesDetail>
        <CategoryTxt>EVALUATION SERVICES</CategoryTxt>
        <Amt>204400</Amt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>283790</DisbursementsCharitablePrpsAmt>
      </OtherProfessionalFeesDetail>
      <OtherProfessionalFeesDetail>
        <CategoryTxt>IT GRANT MANAGEMENT SYSTEM AND CONSULTING</CategoryTxt>
        <Amt>0</Amt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>0</DisbursementsCharitablePrpsAmt>
      </OtherProfessionalFeesDetail>
      <OtherProfessionalFeesDetail>
        <CategoryTxt>PROFESSIONAL FEES</CategoryTxt>
        <Amt>3600</Amt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>3600</DisbursementsCharitablePrpsAmt>
      </OtherProfessionalFeesDetail>
    </OtherProfessionalFeesSchedule>
    <TaxesSchedule documentId="RetDoc2002500001">
      <TaxesDetail>
        <CategoryTxt>Excise Tax</CategoryTxt>
        <Amt>5060</Amt>
        <NetInvestmentIncomeAmt>0</NetInvestmentIncomeAmt>
        <DisbursementsCharitablePrpsAmt>0</DisbursementsCharitablePrpsAmt>
      </TaxesDetail>
    </TaxesSchedule>
  </ReturnData>
</Return>