2026-06-01T11:06:16-05:00 2025-12-31 042571780 AAFCPAS INC 50 WASHINGTON STREET WESTBOROUGH MA 01581 990 2025-01-01 520847477 THE AMERICAN SOCIETY FOR CLINICAL INVESTIGATION INC AMER 7342226050 PO BOX 340 SALINE MI 481760340 JOHN HAWLEY EXECUTIVE DIRECTOR 7342226050 2026-05-28 1 CAITLIN LIMOGES CPA P01633588 5083669100 2026-05-28 2025 2025-03-06 01:10:19Z JOHN HAWLEY PO BOX 340 SALINE MI 481760340 11603205 0 X WWW.THE-ASCI.ORG X 1908 DE PUBLICATION OF RESEARCH JOURNALS AND DISSEMINATION OF RELATED INFORMATION. 13 10 43 13 0 0 1112708 820300 5521994 6219748 1014064 829094 199504 160973 7848270 8030115 152500 148500 0 0 4476009 5104993 0 0 0 2069668 2647356 6698177 7900849 1150093 129266 15542883 16439989 942062 911171 14600821 15528818 X THE AMERICAN SOCIETY FOR CLINICAL INVESTIGATION SEEKS TO SUPPORT THE SCIENTIFIC EFFORTS, EDUCATIONAL NEEDS, AND CLINICAL ASPIRATIONS OF PHYSICIAN-SCIENTISTS TO IMPROVE THE HEALTH OF ALL PEOPLE. 0 0 4483210 5898711 THIS SOCIETY IS ORGANIZED AND OPERATED EXCLUSIVELY FOR EDUCATIONAL AND SCIENTIFIC PURPOSES AND FOR NO OTHER PURPOSE. THE OBJECTIVES OF THE CORPORATION, AS EXPRESSED IN THE 1908 CONSTITUTION ARE: THE ADVANCEMENT OF MEDICAL SCIENCE; THE CULTIVATION OF CLINICAL RESEARCH BY THE METHODS OF THE NATURAL SCIENCES; THE CORRELATION OF SCIENCE WITH THE ART OF MEDICAL PRACTICE; THE ENCOURAGEMENT OF SCIENTIFIC INVESTIGATION BY THE MEDICAL PRACTITIONER; AND THE DIFFUSION OF A SCIENTIFIC SPIRIT AMONG ITS MEMBERS. TO THIS END THE SOCIETY PUBLISHES TWO BIOMEDICAL JOURNALS, THE JOURNAL OF CLINICAL INVESTIGATION AND JCI INSIGHT, BOTH PEER-REVIEWED BIOMEDICAL RESEARCH JOURNALS THAT ARE AVAILABLE WORLDWIDE TO MEMBERS AND NON MEMBERS ALIKE, WITH ALL RESEARCH CONTENT FREELY AVAILABLE WITHOUT RESTRICTION OF ANY KIND. IN 2025, THE ASCI PUBLISHED 499 RESEARCH ARTICLES IN THE JOURNAL OF CLINICAL INVESTIGATION AND 522 RESEARCH ARTICLES IN JCI INSIGHT. 2540076 148500 THE ASCI IS DEDICATED TO THE ADVANCEMENT OF RESEARCH THAT EXTENDS OUR UNDERSTANDING AND IMPROVES THE TREATMENT OF HUMAN DISEASES, AND MEMBERS ARE COMMITTED TO MENTORING FUTURE GENERATIONS OF PHYSICIAN-SCIENTISTS. THE ASCI CONSIDERS THE NOMINATIONS OF SEVERAL HUNDRED PHYSICIAN-SCIENTISTS FROM THE UNITED STATES AND ABROAD EACH YEAR AND ELECTS UP TO 100 NEW MEMBERS EACH YEAR FOR THEIR SIGNIFICANT RESEARCH ACCOMPLISHMENTS. AN ANNUAL MEETING IS HELD TO HONOR THE NEWLY ELECTED MEMBERS, TO FOSTER THE DIFFUSION OF SCIENTIFIC SPIRIT AMONG MEMBERS, AND TO MENTOR YOUNG INVESTIGATORS. 7023286 1 1 0 0 0 0 0 0 0 1 1 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 93 0 1 43 1 0 0 0 0 0 0 0 0 0 0 0 0 X 13 10 0 0 1 0 0 0 0 1 0 0 0 1 1 1 1 1 1 1 1 0 CA X KAREN GUTH MANAGING DIRECTOR 7342226050 PO BOX 340 SALINE MI 481760340 ELIZABETH M MCNALLY MD PHD JCI EDITOR IN CHIEF 21.00 X X 50000 0 0 OLIVER EICKELBERG JCI INSIGHT EDITOR IN CHIEF 21.00 X X 50000 0 0 STEPHEN CHAN VICE PRESIDENT, JCI INSIGHT DEPUTY EDITOR 15.00 X X 10000 0 0 JULIE ANNE BASTARACHE MD PRESIDENT ELECT 5.00 X X 0 0 0 PRISCILLA Y HSUE M D PRESIDENT 5.00 X X 0 0 0 GOUTHAM NARLA MD PHD SECRETARY-TREASURER 5.00 X X 0 0 0 ELIZABETH K SPELIOTES MD PHD MPH SECRETARY-TREASURER (UNTIL 4/25) 1.00 X X 0 0 0 ANNA GREKA MDPHD IMMEDIATE PAST PRESIDENT 5.00 X X 0 0 0 BENJAMIN HUMPHREYS MD PHD IMMEDIATE PAST PRESIDENT (UNTIL 4/25) 1.00 X X 0 0 0 SUSAN CHENG MD MMSC MPH COUNCILOR 1.00 X 0 0 0 RAJAN JAIN MD COUNCILOR 1.00 X 0 0 0 OLUJIMI AJIJOLA COUNCILOR 1.00 X 0 0 0 JENNIFER YU COUNCILOR 1.00 X 0 0 0 TAMIA HARRIS-TYRON COUNCILOR 1.00 X 0 0 0 DAN BAROUCH COUNCILOR 1.00 X 0 0 0 VIJAY G SANKARAN MD PHD COUNCILOR (UNTIL 4/25) 1.00 X 0 0 0 HEIDI H KONG MD COUNCILOR (UNTIL 4/25) 1.00 X 0 0 0 JOHN HAWLEY EXECUTIVE DIRECTOR 45.00 X 382355 0 53450 KAREN GUTH MANAGING DIRECTOR 45.00 X 360687 0 73177 SARAH C JACKSON EXECUTIVE EDITOR 45.00 X 147161 0 47750 COLLEEN MCGARRY PROGRAMS DIRECTOR 45.00 X 140516 0 14032 MAYA HOPTMAN ASSOCIATE DIRECTOR 40.00 X 120421 0 34358 CORINNE WILLIAMS SENIOR SCIENCE EDITOR 40.00 X 113841 0 23219 ELIZABETH EASTER PROGRAMS MANAGER 40.00 X 123669 0 12354 1498650 0 258340 8 0 1 0 BOAST COMMUNICATIONS 8232 TOMPATA TRAIL MILLVILLE CA 96062 PR RESEARCH AND COMMUNICATIONS 156635 1 820300 820300 ARTICLE PROCESSING FEES 513190 5197482 5197482 MEMBERSHIP DUES 513190 665820 665820 ANNUAL MEETING REVENUE 513190 328231 328231 ADVERTISING 541800 28215 28215 6219748 453523 453523 153779 153779 3948661 3573090 375571 375571 375571 OTHER INCOME 900099 7194 7194 7194 8030115 5898711 0 1311104 21000 21000 127500 127500 979669 610108 369561 3077803 2989685 88118 329302 326839 2463 450481 425508 24973 267738 243592 24146 20480 20480 50950 50950 76570 76570 342058 316511 25547 19107 19107 7647 7647 136509 121144 15365 8466 7145 1321 1277704 1267634 10070 25648 22058 3590 38201 38201 EDITORS' HONORARIA 495000 495000 OTHER 130123 12696 117427 PRINTING AND PUBLICATIO 5627 5627 CERTIFICATES/PLAQUES 5512 5512 7754 6620 1134 7900849 7023286 877563 0 1155382 1058533 403250 500000 129300 214332 141019 154945 489934 448922 42350 41012 13671582 14471167 15542883 16439989 260592 323761 681470 587410 942062 911171 X 12585172 12870049 2015649 2658769 14600821 15528818 15542883 16439989 129266 798731 0 X X 0 1 X 1 0 X 71425 92625 118140 1112708 820300 2215198 5127360 4903958 5041284 5521994 6219748 26814344 5198785 4996583 5159424 6634702 7040048 29029542 13550 30300 20375 26690 25735 116650 0 13550 30300 20375 26690 25735 116650 28912892 561127 573657 634265 643539 607302 3019890 561127 573657 634265 643539 607302 3019890 10757 7194 17951 5759912 5570240 5793689 7288998 7654544 32067383 0.90160 0.89650 0.09420 0.09870 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 9874924 1169488 365000 1457788 9221624 9079030 400000 770294 374400 9874924 8437991 1011039 370000 9079030 10371201 -1576010 357200 8437991 9833345 860369 322513 10371201 0.95400 0.04600 0 0 489934 448922 41012 0 41012 X 8752276 798731 798731 7953545 76570 76570 8030115 7824279 0 7824279 76570 76570 7900849 PART V, LINE 4: DURING 2014, ASCI ESTABLISHED TWO BOARD DESIGNATED ENDOWMENTS: THE BOARD DESIGNATED ENDOWMENT, WHICH REPRESENTS FUNDS SET ASIDE BY THE BOARD OF DIRECTORS TO GENERATE INVESTMENT INCOME FOR OPERATIONS. THE BOARD DESIGNATED ENDOWMENT IS INTENDED TO FUNCTION SIMILARLY TO A DONOR-RESTRICTED ENDOWMENT. THE ASCI PROGRAM FUND, WHICH REPRESENTS A FUND ESTABLISHED TO GENERATE EARNINGS TO SUPPORT BOARD-DESIGNATED PROGRAMS. THE ENDOWMENT CORPUS WILL BE HELD IN PERPETUITY AND THE EARNINGS WILL BE USED TO FUND AWARDS EACH YEAR AS DEFINED BY A SPENDING POLICY. PART X, LINE 2: THE SOCIETY ACCOUNTS FOR UNCERTAINTY IN INCOME TAXES IN ACCORDANCE WITH ASC TOPIC, INCOME TAXES. THIS STANDARD CLARIFIES THE ACCOUNTING FOR UNCERTAINTY IN TAX POSITIONS AND PRESCRIBES A RECOGNITION THRESHOLD AND MEASUREMENT ATTRIBUTE FOR THE FINANCIAL STATEMENTS REGARDING A TAX POSITION TAKEN OR EXPECTED TO BE TAKEN IN A TAX RETURN. THE SOCIETY HAS DETERMINED THAT THERE ARE NO UNCERTAIN TAX POSITIONS WHICH QUALIFY FOR EITHER RECOGNITION OR DISCLOSURE IN THE FINANCIAL STATEMENTS AT DECEMBER 31, 2025. THE SOCIETY'S INFORMATION AND TAX RETURNS ARE SUBJECT TO EXAMINATION BY THE FEDERAL GOVERNMENT. 1 WEILL CORNELL MEDICINE 1300 YORK AVENUE NEW YORK NY 10065 131623978 501C3 10000 0 ASCI/BWF/PSSF/DRCF/GENENTECH PHYSICIAN-SCIENTIST WORKSHOP, 8/18/25 - 8/19/25 1 THE STANLEY J. KORSMEYER AWARD 1 20000 YOUNG PHYSICIAN SCIENTIST AWARDS 50 24500 THE SELDIN-SMITH AWARD 1 30000 EMERGING-GENERATION AWARDS 26 13000 THE MARIAN W. ROPES, MD, AWARD 1 10000 THE LOUIS W. SULLIVAN, MD, AWARD 1 10000 THE BRUCE F. SCHARSCHMIDT & PEGGY S. CRAWFORD AWARD 1 20000 PART I, LINE 2: THE STANLEY J. KORSMEYER AWARD IS NAMED IN HONOR OF DR. KORSMEYER, WHO WAS THE FIRST RECIPIENT OF THE AWARD IN 1998 AND WHO PASSED AWAY IN MARCH 2005. THE ANNUAL AWARD RECOGNIZES THE OUTSTANDING ACHIEVEMENTS OF ASCI MEMBERS IN ADVANCING KNOWLEDGE IN A SPECIFIC FIELD AND IN MENTORING FUTURE GENERATIONS OF LIFE-SCIENCE RESEARCHERS. THE AWARD RECIPIENTS RECEIVE AN UNRESTRICTED $20,000 GRANT FROM THE SOCIETY AND PRESENTS THE AWARD LECTURE AT THE SOCIETY'S ANNUAL MEETING. THE ASCI COUNCIL YOUNG PHYSICIAN-SCIENTIST AWARDS RECOGNIZE YOUNG PHYSICIAN SCIENTISTS WHO ARE SUPPORTED BY NIH K OR SIMILAR SIGNIFICANT CAREER-DEVELOPMENT AWARDS, ARE EARLY IN THEIR FIRST FACULTY APPOINTMENT, AND HAVE MADE NOTABLE ACHIEVEMENTS IN THEIR RESEARCH. THE DONALD SELDIN-HOLLY SMITH AWARD FOR PIONEERING RESEARCH HONORS OUTSTANDING EARLY-STAGE PHYSICIAN-SCIENTISTS WHO HAVE DEMONSTRATED EXCEPTIONAL CREATIVITY AND ACCOMPLISHMENTS IN BIOMEDICAL RESEARCH. THE EMERGING GENERATION AWARDS RECOGNIZE POST-MD, PRE-FACULTY APPOINTMENT PHYSICIAN-SCIENTISTS WHO ARE MEANINGFULLY ENGAGED IN IMMERSIVE RESEARCH. THE MARIAN W. ROPES, MD, AWARD RECOGNIZES THE SIGNIFICANT SCHOLARLY ACHIEVEMENTS OF A MIDDLE-CAREER WOMAN PHYSICIAN-SCIENTIST. THE LOUIS W. SULLIVAN, MD, AWARD RECOGNIZES THE SIGNIFICANT SCHOLARLY ACHIEVEMENTS OF A MIDDLE-CAREER PHYSICIAN-SCIENTIST WHO IS UNDERREPRESENTED IN MEDICINE AND SCIENCE. THE BRUCE F. SCHARSCHMIDT & PEGGY S. CRAWFORD TRANSLATIONAL MEDICINE DISTINGUISHED LECTURESHIP AND AWARD RECOGNIZES IMPORTANT CONTRIBUTIONS TO THE DEVELOPMENT OF HIGH-IMPACT DIAGNOSTICS OR THERAPEUTICS FOR PATIENTS. X X X X X 0 0 0 0 0 0 0 0 0 JOHN HAWLEY EXECUTIVE DIRECTOR 365758 0 16597 0 0 0 41713 0 11737 0 435805 0 0 0 KAREN GUTH MANAGING DIRECTOR 344889 0 15798 0 0 0 39778 0 33399 0 433864 0 0 0 SARAH C JACKSON EXECUTIVE EDITOR 147161 0 0 0 0 0 16016 0 31734 0 194911 0 0 0 MAYA HOPTMAN ASSOCIATE DIRECTOR 120421 0 0 0 0 0 12378 0 21980 0 154779 0 0 0 COLLEEN MCGARRY PROGRAMS DIRECTOR 140516 0 0 0 0 0 14032 0 0 0 154548 0 0 0 FORM 990, PART VI, SECTION A, LINE 4 THE BYLAWS WERE AMENDED IN 2025 TO ADD ARTICLE V - MANAGEMENT AND STAFF, AND ARTICLE XI - AMENDMENTS TO THE BYLAWS. FORM 990, PART VI, SECTION A, LINE 8B ASCI DOES NOT HAVE SUB-COMMITTEES WITHIN THE BOARD OF DIRECTORS WHICH ACT ON BEHALF OF THE GOVERNING BODY. FORM 990, PART VI, SECTION B, LINE 11B A COPY OF THE FEDERAL FORM 990 IS REVIEWED IN DETAIL BY MANAGEMENT AND A COPY IS THEN PRESENTED TO THE BOARD FOR THEIR REVIEW BEFORE IT IS FILED. FORM 990, PART VI, SECTION B, LINE 12C ASCI AND THE JCI BOARD MEMBERS SELF REPORT ON POTENTIAL CONFLICTS OF INTEREST VIA WRITTEN STATEMENTS AND RECUSE THEMSELVES FROM DISCUSSIONS THAT PROPOSE A POTENTIAL CONFLICT. THE EXECUTIVE DIRECTOR RETAINS THESE WRITTEN STATEMENTS AND MONITORS ANY POTENTIAL CONFLICTS. JCI BOARD MEMBERS ARE NOT ASSIGNED TO REVIEW MANUSCRIPTS THAT PROPOSE A POTENTIAL CONFLICT. FORM 990, PART VI, SECTION B, LINE 15 THE BOARD OF DIRECTORS APPROVES EMPLOYMENT CONTRACTS FOR EXECUTIVE DIRECTOR AND MANAGING DIRECTOR AS WELL AS PERFORMING A COMPETITIVE SALARY REVIEW. FORM 990, PART VI, SECTION C, LINE 19 ASCI MAKES ITS GOVERNING DOCUMENTS, CONFLICT OF INTEREST STATEMENT AND FINANCIAL STATEMENTS AVAILABLE TO THE PUBLIC UPON REQUEST. THE CONFLICT OF INTEREST STATEMENT IS ALSO POSTED ON ASCI'S WEBSITE. FORM 990, PART XI, LINE 2C THE FINANCE COMMITTEE IS RESPONSIBLE FOR THE OVERSIGHT OF THE AUDIT.